Paromomycin sulfate

CAS No: 1263-89-4
Appearance: A white or yellowish-white powder
Standard: USP
Application: antibiotic Supply Ability: 1000kg per month
Purity: ≥99%
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Can't sell to individuals
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Product Introduction

We supply Paromomycin sulfate API

We offer Paromomycin sulfate API as a part of our product portfolio. it is a broad- diapason antibiotic that's generally used to treat colorful bacterial infections. The API is produced in compliance with GMP norms to insure its high quality and efficacity. Our platoon of experts also nearly monitors the entire product process to insure thickness and trustability of the product. We prioritize client satisfaction and hence offer timely delivery, competitive prices and excellent client support services. Whether you're a pharmaceutical manufacturer or a exploration association, we've the capability to fulfill your conditions for the API.

 

What is Paromomycin sulfate?

it is an antibiotic used to treat parasitic infections caused by amebae and certain bacteria. It's a type of aminoglycoside which works by precluding the growth and spread of the spongers, thereby stopping the infection from spreading. It's effective against a wide range of spongers including Entamoeba histolytica, Giardia lamblia, and some types of bacteria likeE. coli and Salmonella.

it is generally administered orally or intravenously and is fleetly absorbed by the body. It's metabolized in the liver and excreted through the feathers, making it safe for individualities with order and liver issues. The lozenge and duration of treatment depend on the type and inflexibility of the infection, and may vary from person to person.

it is extensively used in the pharmaceutical assiduity to produce colorful phrasings that are used to treat parasitic infections. It's also used as a feed cumulative in beast husbandry to help and control parasitic infections in beast. still, it's important to follow the lozenge instructions precisely to help the development of medicine resistance or other adverse goods.

Overall, it is a largely effective treatment option for individualities suffering from parasitic infections caused by amebae and bacteria. It's extensively available and can be used across different age groups with fairly low pitfalls of side goods. Its effectiveness and safety have made it a popular choice for treating colorful parasitic infections in both mortal and beast populations.

 

Basic Information

Product Name: paromomycin sulfate

CAS: 1263-89-4

MF:C23H47N5O18S

MW:713.71

EINECS:215-031-7

MDL No.:MFCD00079278

Structural formula:

product-1-1

Application: antibiotic

Origin: China

Delivery Time: in stock

 

Technical Specification

DETERMINATION

SPECIFICATION

RESULTS

Appearance

A white or yellowish-white powder

White powder

Identification

TCL: The RF Value of principal spot obtained from the test solution corresponds to that obtained from the standard solution

Conform

Sulphate: it meets the requirements of the tests for sulphate

Conform

Specific rotation

+50°~ +55°

+53°

pH-value

5.0-7.5

6.2

Residue on ignition

≤2.0%

0.6%

Loss on drying

≤5.0%

3.8%

Bulk density

0.25g/ml~0.65mg/ml

0.32mg/ml

Assay(on the dried basis)

≥675 IU/mg

711 IU/mg

CONCLUSION

CONFORM TO USP42

Package 1kg, 25kg or according to your demands

Storage conditions: Preserve in tightly closed container between 2~8℃

Transportation conditions Transportation at room temperature

Shelf Life 24 months

 

Application:

Paromomycin sulfate, also known as Paramycin Sulfate, is an antibiotic used primarily for the treatment of intestinal infections caused by certain spongers. Then are its some applications:

Intestinal Parasitic Infections: it is generally used in the treatment of intestinal infections caused by spongers similar as Entamoeba histolytica, Giardia lamblia, and Cryptosporidium parvum. These infections can lead to diarrhea, abdominal pain, and other gastrointestinal symptoms.

Amoebiasis: It's effective against amoebiasis, which is caused by the sponger Entamoeba histolytica. This infection can lead to dysentery( bloody diarrhea) and can spread to other organs, causing serious complications if undressed.

Giardiasis: it is used to treat giardiasis, an intestinal infection caused by the sponger Giardia lamblia. Symptoms include diarrhea, abdominal cramps, bloating, and nausea.

Cryptosporidiosis: This drug is also used in the treatment of cryptosporidiosis, an infection caused by the sponger Cryptosporidium parvum. Immunocompromised individualities, similar as those with HIV/ AIDS, are particularly susceptible to severe symptoms from this infection.

seditious Bowel complaint( IBD): In some cases, it may be used off- marker in the treatment of seditious bowel complaint( IBD), similar as Crohn's complaint, especially when there's substantiation of parasitic involvement aggravating the condition.

it works by snooping with the growth and reduplication of these spongers, thereby helping to exclude the infection. It's generally administered orally and is generally well- permitted, however like all specifics, it can have side goods and relations that need to be considered under medical supervision.

 

Biological activity

Paramycin Sulfate is an aminoglycoside antibiotic that acts on non resistant cells and inhibits protein conflation by binding to 16S ribosomal RNA.

 

In vitro research

it is an aminoglycoside antibiotic that exhibits excellent antibacterial exertion against Gram negative and numerous Gram positive bacteria, as well as some protozoa and tapeworms. In vitro analysis of flagellate perceptivity in mouse macrophage models showed that theL. major andL. tropica strains( ED50s between 1 and 5 μ M) were more sensitive than the L. braziliensis (ED50,<12 μ M) and L. Mexico (ED50,39 μ M) strains. The strain L. donovani is moderately sensitive (ED50, 6 to 18 μ M), except for one Indian strain, DD8, which has an ED50>150 μ M.

 

In vivo research

In experimental models and clinical cases of CL, damage caused byL. major recovered briskly and more completely after treatment with paromycin ointment compared to damage caused byL. Amazonensis andL. Panamensis.

 

Security information

Category: Toxic substances

Toxicity classification: low toxicity

Acute toxicity: Oral LD50 in rats: 21620 mg/kg; Oral administration - mouse LD50: 23500 mg/kg

Flammability hazard characteristics: flammable; Burning produces toxic nitrogen oxides and sulfur oxide smoke

Storage and transportation characteristics: warehouse ventilation, low-temperature drying

Extinguishing agent: dry powder, foam, sand, carbon dioxide, atomized water

 

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Item

Quantity

ETA time

Shipping Method

By Courier

≤50kg

7-15days

Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air

50kg~200kg

3-5days

Fast and cheap

By Sea

Large quantity

20-35days

Cheapest way

Lead time: Within 3 workdays after receiving payment.

 

Payment Term

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Contact Yihui

as a professional Paromomycin sulfate manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply to you ASAP.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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