Paromomycin sulfate
Appearance: A white or yellowish-white powder
Standard: USP
Application: antibiotic Supply Ability: 1000kg per month
Purity: ≥99%
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Can't sell to individuals
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
We supply Paromomycin sulfate API
We offer Paromomycin sulfate API as a part of our product portfolio. it is a broad- diapason antibiotic that's generally used to treat colorful bacterial infections. The API is produced in compliance with GMP norms to insure its high quality and efficacity. Our platoon of experts also nearly monitors the entire product process to insure thickness and trustability of the product. We prioritize client satisfaction and hence offer timely delivery, competitive prices and excellent client support services. Whether you're a pharmaceutical manufacturer or a exploration association, we've the capability to fulfill your conditions for the API.
What is Paromomycin sulfate?
it is an antibiotic used to treat parasitic infections caused by amebae and certain bacteria. It's a type of aminoglycoside which works by precluding the growth and spread of the spongers, thereby stopping the infection from spreading. It's effective against a wide range of spongers including Entamoeba histolytica, Giardia lamblia, and some types of bacteria likeE. coli and Salmonella.
it is generally administered orally or intravenously and is fleetly absorbed by the body. It's metabolized in the liver and excreted through the feathers, making it safe for individualities with order and liver issues. The lozenge and duration of treatment depend on the type and inflexibility of the infection, and may vary from person to person.
it is extensively used in the pharmaceutical assiduity to produce colorful phrasings that are used to treat parasitic infections. It's also used as a feed cumulative in beast husbandry to help and control parasitic infections in beast. still, it's important to follow the lozenge instructions precisely to help the development of medicine resistance or other adverse goods.
Overall, it is a largely effective treatment option for individualities suffering from parasitic infections caused by amebae and bacteria. It's extensively available and can be used across different age groups with fairly low pitfalls of side goods. Its effectiveness and safety have made it a popular choice for treating colorful parasitic infections in both mortal and beast populations.
Basic Information
Product Name: paromomycin sulfate
CAS: 1263-89-4
MF:C23H47N5O18S
MW:713.71
EINECS:215-031-7
MDL No.:MFCD00079278
Structural formula:
Application: antibiotic
Origin: China
Delivery Time: in stock
Technical Specification
DETERMINATION |
SPECIFICATION |
RESULTS |
Appearance |
A white or yellowish-white powder |
White powder |
Identification |
TCL: The RF Value of principal spot obtained from the test solution corresponds to that obtained from the standard solution |
Conform |
Sulphate: it meets the requirements of the tests for sulphate |
Conform |
|
Specific rotation |
+50°~ +55° |
+53° |
pH-value |
5.0-7.5 |
6.2 |
Residue on ignition |
≤2.0% |
0.6% |
Loss on drying |
≤5.0% |
3.8% |
Bulk density |
0.25g/ml~0.65mg/ml |
0.32mg/ml |
Assay(on the dried basis) |
≥675 IU/mg |
711 IU/mg |
CONCLUSION |
CONFORM TO USP42 |
Package 1kg, 25kg or according to your demands
Storage conditions: Preserve in tightly closed container between 2~8℃
Transportation conditions Transportation at room temperature
Shelf Life 24 months
Application:
Paromomycin sulfate, also known as Paramycin Sulfate, is an antibiotic used primarily for the treatment of intestinal infections caused by certain spongers. Then are its some applications:
Intestinal Parasitic Infections: it is generally used in the treatment of intestinal infections caused by spongers similar as Entamoeba histolytica, Giardia lamblia, and Cryptosporidium parvum. These infections can lead to diarrhea, abdominal pain, and other gastrointestinal symptoms.
Amoebiasis: It's effective against amoebiasis, which is caused by the sponger Entamoeba histolytica. This infection can lead to dysentery( bloody diarrhea) and can spread to other organs, causing serious complications if undressed.
Giardiasis: it is used to treat giardiasis, an intestinal infection caused by the sponger Giardia lamblia. Symptoms include diarrhea, abdominal cramps, bloating, and nausea.
Cryptosporidiosis: This drug is also used in the treatment of cryptosporidiosis, an infection caused by the sponger Cryptosporidium parvum. Immunocompromised individualities, similar as those with HIV/ AIDS, are particularly susceptible to severe symptoms from this infection.
seditious Bowel complaint( IBD): In some cases, it may be used off- marker in the treatment of seditious bowel complaint( IBD), similar as Crohn's complaint, especially when there's substantiation of parasitic involvement aggravating the condition.
it works by snooping with the growth and reduplication of these spongers, thereby helping to exclude the infection. It's generally administered orally and is generally well- permitted, however like all specifics, it can have side goods and relations that need to be considered under medical supervision.
Biological activity
Paramycin Sulfate is an aminoglycoside antibiotic that acts on non resistant cells and inhibits protein conflation by binding to 16S ribosomal RNA.
In vitro research
it is an aminoglycoside antibiotic that exhibits excellent antibacterial exertion against Gram negative and numerous Gram positive bacteria, as well as some protozoa and tapeworms. In vitro analysis of flagellate perceptivity in mouse macrophage models showed that theL. major andL. tropica strains( ED50s between 1 and 5 μ M) were more sensitive than the L. braziliensis (ED50,<12 μ M) and L. Mexico (ED50,39 μ M) strains. The strain L. donovani is moderately sensitive (ED50, 6 to 18 μ M), except for one Indian strain, DD8, which has an ED50>150 μ M.
In vivo research
In experimental models and clinical cases of CL, damage caused byL. major recovered briskly and more completely after treatment with paromycin ointment compared to damage caused byL. Amazonensis andL. Panamensis.
Security information
Category: Toxic substances
Toxicity classification: low toxicity
Acute toxicity: Oral LD50 in rats: 21620 mg/kg; Oral administration - mouse LD50: 23500 mg/kg
Flammability hazard characteristics: flammable; Burning produces toxic nitrogen oxides and sulfur oxide smoke
Storage and transportation characteristics: warehouse ventilation, low-temperature drying
Extinguishing agent: dry powder, foam, sand, carbon dioxide, atomized water
Packing & Shipping
Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.
Customization: Customized logo; Customized packaging; Graphic customization
Shipping:
Item |
Quantity |
ETA time |
Shipping Method |
By Courier |
≤50kg |
7-15days |
Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air |
50kg~200kg |
3-5days |
Fast and cheap |
By Sea |
Large quantity |
20-35days |
Cheapest way |
Lead time: Within 3 workdays after receiving payment.
Payment Term
Why Choose Xi'an Yihui?
Customer feedback
Xi'an Yihui certificates
Xi'an Yihui Factory & Warehouse
Contact Yihui
as a professional Paromomycin sulfate manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply to you ASAP.
our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937
Send Message
If you have any enquiry about quotation or cooperation, please feel free to email us at E-mailor use the following enquiry form. Our sales representative will contact you within 24 hours.Thank you for your interest in our products.