Ethynyl Estradiol

CAS: 57-63-6
Appearance: White to Light yellow to Light orange Powder
Standard: BE/USP
Brand: YIHUI
Packing: 100g;1kg;25kg
Supply Ability: 1000kg per month
Shelf Life: Two years
Payment: T/T, LC or DA
Sample: available
Delivery Time: Ready Stock in Local Warehouse,1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL,FedEx,TNT,EMS,By Sea,By Air
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
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Product Introduction

What is Ethynyl Estradiol?

Ethynyl Estradiol is a effective synthetic estrogen having a place with the ethinyl estradiol class of hormones. It assumes a significant part in different drug and industrial applications, known for its exceptional properties and various purposes. Yihui stands as a leading manufacturer and supplier of Ethynyl Estradiol, adhering to international standards and holding certifications such as ISO, Kosher, Halal, and GMP.

Ethynyl Estradiol, or EE2, is a manufactured subordinate of the regular estrogen 17β-estradiol. Yihui's CAS 57-63-6 is carefully synthesized to fulfill the highest quality standards. This item is broadly perceived for its  stability, purity, and consistent performance.


Basic Information

Product Name: Ethynyl estradiol

CAS: 57-63-6

MF:C20H24O2

MW:296.41

EINECS:200-342-2

MDL No.:MFCD00003690

Purity: 99%

Package:1kg;5kg;25kg

Used:  Pharma grade & Lab research

Stability: Stable

Structural formula:

57-63-6.webp

Specification Parameter:

Item

Specification

Results

Appearance

White or off-white crystalline powder

off-white crystalline powder

Solubility

Practically insoluble in water, freely   soluble in ethanol(96% per cent), it dissolves in dilute alkaline solutions.

Conforms

Identification

TLC: The principal spot in the   chromatogram obtained with the test solution is similar in position, colour,   fluorescence and size to the principal spot in the chromatogram obtained with   the reference solution.

Conforms

IR: The spectra abtained with the sample   should be consistent to that of the reference standard.

Loss on drying

≤1.0%

0.45%

Related substances

(HPLC, % area)

Impurity B≤0.5%

0.02%

Impurity H≤0.2%

Not detected

Impurity I≤0.2%

Not detected

Impurity K≤0.2%

Not detected

Impurity C≤0.15%

Not detected

Impurity F≤0.15%

Not detected

Unspecified impurities≤0.10%

0.08%

Total impurities≤0.8%

0.38%

Assay(HPLC, %w/w)

97.0~102.0% (on the dried basis)

99.5%

Residual Solvents

(GC, %w/w)

Acetone≤5000ppm

572ppm

Toluene ≤890ppm

Not detected

Tetrahydrofuran≤720ppm

Not detected

Isobutyl alcohol≤5000ppm

Not detected

Benzene≤2ppm

Not detected

Particle Size

D[90]≤10μm

3.567um

Conclusion

The product complies with specification in BP2017

Chemical Composition:

ComponentPercentage
Ethynyl Estradiol99.5%
Impurities≤ 0.5%

Effects and Functions:

Ethynylestradiol assumes an essential part in hormonal treatments, fundamentally in oral contraceptives. Because of its oestrogenic properties, it is utilized to control the female reproductive system, treat feminine problems and assuage menopausal side effects. Also, it applications in hormone replacement therapy and treating certain types of cancers.

The product, a manufactured estrogen, copies the impacts of the natural hormone, assisting with keeping up with bone thickness, cardiovascular wellbeing, and general healthy Its adequacy in contraceptive formulations lies in its capacity to smother ovulation and modify cervical bodily fluid consistency, forestalling sperm penetration.

Synthesis Process:

The production of the product is a multistep process. It begins with the acetylation of appropriate starting materials, which introduces particular functional groups.This is trailed by deprotonation, which is the expulsion of a proton from a molecule to deliver an adversely charged species. The molecule  is then alkylated, which includes the addition of an alkyl group.

Cautious checking is expected during the synthesis process to guarantee exact creation of the ethynyl bunch in the product. This group is fundamental to the compound's structure and function.

To attain the necessary purity of Ethynyl Estradiol, purifying processes are conducted. These may include processes such as crystallization, which involves dissolving the compound in a suitable solvent and slowly forming crystals. Furthermore, chromatography can be used to separate and isolate the desired product from contaminants.

These means in the synthesis process are directed with fastidious meticulousness to guarantee the production of high-quality the product.

Quality Standards :

Yihui adheres to stringent quality standards to produce the product of the highest caliber. Stringent testing processes are implemented throughout the manufacturing stages to ensure purity, stability, and compliance with international specifications. Our commitment to quality is underscored by certifications such as ISO, Kosher, Halal, and GMP.

Application Fields in Various Industries :

Ethynylestradiol, with its wide range of applications, is a valuable compound across various industries.

In the pharmaceutical sector, it plays a crucial role as a component of hormonal therapies. Its inclusion in contraceptives and hormone replacement formulations highlights its significance in women's health. To successfully control period, forestall ovulation, and give contraception, the product is often used in conjunction with other hormones. It additionally mitigates side effects related with hormonal uneven characters, like those accomplished during menopause.Additionally, the product finds applications in treating certain types of cancers, such as breast and prostate cancer, where hormonal interactions play a significant role.

Except drugs, the product is used in research labs concentrating on studying hormonal interactions. Its synthetic nature and comparability to normal estrogen make it a significant instrument for investigating hormone-related conditions and growing new treatment techniques. Scientists concentrate on the impacts of the product on different physiological cycles and use it to comprehend the mechanisms of hormone action.

Contact Us:

Yihui takes pride in being a reliable Ethynyl Estradiol manufacturer, ensuring product quality aligned with international standards. The attainment of ISO, Kosher, Halal, and GMP certifications underscores our commitment to excellence. For inquiries or purchases, contact us at sales@yihuipharm.com.

In conclusion, the product stands as a versatile compound with profound effects in pharmaceutical and industrial applications, and Yihui stands as your trusted partner in ensuring its quality and accessibility.

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