What is Pizotifen Malate?

Pizotifen Malate is an Active Pharmaceutical component, its chemical name is( 4S, 9S)- 4-( 1- methyl-4-piperidinylidene)( 4,3- c) carbazole -6,11-dione hydrogen 2- butanedioate. Its molecular formula is C19H21N3O4 · C4H6O4, its relative molecular mass is413.45 g/ spook, and its CAS number is 5189-11-7. It's a white to out-white solid, slightly answerable in water, fluently answerable in chloroform, methanol, and acetone.

It's generally used to help migraines. Its raw accouterments are generally sourced through chemical conflation. Specifically, its conflation requires several way, including nitration of propenylphenol, condensation, nitration, reduction, acylation, and so on. The final product is attained through crystallization and sanctification processes, performing in high chastity. The quality and chastity of the raw accouterments are essential factors affecting the final medicine quality and efficacity. thus, manufacturers frequently rigorously control and test the quality of the raw accouterments to ensure compliance with applicable norms and regulations.

It was initially developed by Swiss pharmaceutical company Sandoz in the late 1960s and first launched in 1969 under the brand name Sandomigran. Similar products were later introduced by other companies. Therefore, it is usually used as a choice for preventive treatment rather than acute treatment during migraine attacks.

Over time, its application scope has gradually expanded. Currently, it is still under constant research and development to expand its application prospects in the treatment of other diseases.

Basic Information

Quality standard

Stability & storage

Pizotifen Malate stability is affected by temperature, humidity, light exposure and pH environment. The following is the stability information of the drug raw material:

Thermal stability its content changes lower than 5 when stored at 80 ℃ for 28 days.

moisture stability its content changes lower than 5 when stored at 75 relative moisture for 28 days.

Light stability it's unstable under UV or visible light exposure, fluently decomposes, and leads to a drop in medicine content.

pH stability it's stable in the pH range of 4

8, and is easy to putrefy under acidic or alkaline conditions.

To insure its stability, it should be stored it in a dry, cool, dark, and low moisture terrain. At the same time, it's also necessary to avoid mixing with other medicines and prolonged contact with air and water to avoid affecting the quality of the raw accoutrements .

its solubility refers to the maximum quantum of medicine that dissolves into a result in a unit time when equilibrium is reached between the solid face and the result at a certain temperature.

it is a salt compound. Its solubility is affected by various factors such as solvent type, temperature, and pH value ect. The following are its solubilities in different solvents:

Water: 0.9mg/mL

Ethanol: 6.3mg/mL

Methanol: 1.5mg/mL

DMSO: 30mg/mL

It should be noted that solubility data is for reference only, and specific values may be influenced by various factors in the actual environment. For practical applications, it is recommended to determine the solubility of drugs based on specific environments and conditions, in order to more accurately prepare and use them.

Packing & Shipping

Quilting 1kg/ antipode bag; 5kg/ tinderbox; 25kg/ fiber barrel; or packing as your request.

CustomizationCustomized totem; tailored packaging; Graphic customization

Shipping

Payment Term

Why Choose Xi'an Yihui?

Customer feedback

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Xi'an Yihui Factory & Warehouse

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition, and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, Xi'an Yihui company as a professional Pizotifen Malate manufacturer has strong technical strength and advanced production equipment, and is committed to providing customers with high-quality, efficient, and reliable drug raw materials. if you need it, pls feel free to contact us any time. we will reply to you ASAP.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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