Paclitaxel powder Supplier

Xi'an Yihui Company is a professional manufacturer of Purity Paclitaxel.We can induce Paclitaxel Powder with a99.9% content. It can be employed in food, drug, health care particulars, or cosmetics and meet USP, BP, EP, CP norms. We can offer you products of the loftiest quality at the most competitive rates. Your best option for a reputable pure Paclitaxel supplier is Xi'an Yihui Company!

What is Paclitaxel powder?

Paclitaxel is a white crystalline powder that belongs to the class of ester composites. Its chemical name is- Epoxy resin-- hexahydroxytax-11-en-9-one 4,10- diacetate 2- benzoate 13- ester with( 2R, 3S)- N- benzoyl-3-phenylisoserine. It's uprooted from the dinghy of the Pacific yew tree in the United States, and can also be attained through semi-synthesis. Its chemical structure consists of multiple cyclic sweet hydrocarbon rings, with a large four-ring structure. Its molecular formula is C47H51NO14, with a molecular weight of853.91 g/ spook, and its CAS number is 33069-62-4.

It's a monomeric diterpenoid emulsion uprooted from the dinghy of the natural factory yew tree, which is a complex secondary metabolite and the only medicine presently known that can promote microtubule polymerization and stabilize polymerized microtubules. Isotope dogging indicates that paclitaxel binds only to polymerized microtubules and doesn't reply with unpolymerized tubulin dimers. After cells are exposed to paclitaxel Chemicalbook, a large number of microtubules accumulate in the cell, and the accumulation of these microtubules interferes with colorful functions of cells, especially stopping cell division in the mitotic phase and blocking the normal division of cells. ThroughII.- III. clinical exploration, paclitaxel is substantially suitable for ovarian cancer and bone cancer, and has a certain effect on lung cancer, colorectal cancer, carcinoma, head and neck cancer, carcinoma, and brain excrescence.

It's a monomeric biterpenoid emulsion uprooted from the dinghy of the natural factory yew tree, which is a complex secondary metabolite and the only medicine presently known that can promote microtubule polymerization and stabilize polymerized microtubules. Isotope dogging indicates that paclitaxel binds only to polymerized microtubules and doesn't reply with unpolymerized tubulin dimers. After cells are exposed to paclitaxel Chemicalbook, a large number of microtubules accumulate in the cell, and the accumulation of these microtubules interferes with colorful functions of cells, especially stopping cell division in the mitotic phase and blocking the normal division of cells. ThroughII.- III. clinical exploration, paclitaxel is substantially suitable for ovarian cancer and bone cancer, and has a certain effect on lung cancer, colorectal cancer, carcinoma, head and neck cancer, carcinoma, and brain excrescence.

Basic Information

Quality standard

Production methods

There are two main methods for the production of Paclitaxel powder, natural source and semi-synthesis.

Natural source production method

Initially, it was isolated from the bark of the Pacific yew tree. The method involves the following steps:

Collection and analysis of plant specimens.

Determination of the growth location, harvesting time, and part of the Pacific yew tree, and collection and processing of raw materials.

The collected raw accouterments are first subordinated to primary processing way similar as sorting, crushing, and webbing, and also uprooted and separated.

The attained admixture is subordinated to multiple separations, sanctifications, and re-crystallizations using ways similar as chromatography, spectroscopy, electrophoresis, birth, and crystallization, eventually performing in largely pure products.

Semi-synthesis production method

Currently, the semi-synthesis method has become the main industrial production method. The specific steps are as follows:

Starting with cyclohexane-1,3-diol, undergo hydrogenation reaction to obtain (−)-3-(3,5-di-tert-butylphenyl)cyclohexene-1,2-diol.

Perform a hydroxyethylation reaction on the above product to obtain (−)-3-(3,5-di-tert-butylphenyl)cyclohexene-1,2-diol-4-hydroxyethyl ether.

Undergo epoxidation reaction on the above product to obtain (−)-10-hydroxy-13-(2-methoxy-2-methylpropanoyloxy)-5β,20-epoxytax-11-en-9-one.

Perform a deacetylation reaction on the above product to obtain its precursor compound.

Eventually, after deprotecting under alkaline conditions and using styles similar to are-crystallization and chromatography for separation and sanctification, a high-chastity product is attained.

Overall, its product requires multiple way, including collection and processing of raw accoutrements, as well as multiple processes similar as separation, birth, conversion, and-crystallization. Meanwhile, in order to gain advanced yield and better chastity, it's necessary to rigorously control parameters such as temperature, pressure, response time, and lozenge during the product process to ensure product quality and stability.

Function 

1. Paclitaxel is a cancer drug that works by snooping with the normal function of cancer cells, causing them to stop growing and dividing. Specifically, it binds to and stabilizes microtubules within the cell, precluding them from breaking down and enabling the cell to divide and gain.

2. It's generally used to treat a variety of cancers, including bone cancer, ovarian cancer, and lung cancer. It's generally administered intravenously and can be used alone or in combination with other specifics.

3. One of its benefits is that it has been shown to be effective against cancer cells that are resistant to other chemotherapy medicines. It also has fairly many side goods compared to other chemotherapy specifics, similar as nausea and vomiting.

4. While It can be an effective cancer treatment, it isn't without pitfalls. It can beget some side goods, including hair loss, impassiveness or chinking in the hands and bases, and low blood cell counts. In some cases, it can also beget antipathetic responses, so cases should be covered nearly during treatment.

5. Despite these pitfalls, It has proven to be an important tool in the fight against cancer. Through its capability to disrupt cancer cell function and help cell division, it has helped innumerous cases in their battle against this ruinous complaint.

6. Overall, its ability to target cancer cells and disrupt their normal function makes it an important medication in the treatment of many types of cancer. Despite its potential side effects, it has been proven to be an effective treatment option for many cancer patients, and has helped improve survival rates and quality of life for those battling this disease.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.

Customization:Customized logo;Customized packaging;Graphic customization

Shipping:

Payment Term

Why Choose Xi'an Yihui?

Customer feedback

Xi'an Yihui certificates

Xi'an Yihui Factory & Warehouse

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition, and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

As a Paclitaxel factory, we will provide our customers with high-quality Paclitaxel powder. We will establish a complete service system, provide specialized technical support and after-sales services, and make every effort to improve customer satisfaction.if you need it, pls feel free to contact us at any time. we will reply to you ASAP.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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