What is Cyclophosphamide Powder?

Cyclophosphamide Powder is a commonly used alkylating agent and antineoplastic drug. At room temperature, Cyclophosphamide API is a white, crystalline, or powdered substance that liquefies upon losing crystalline water. It is stable at room temperature. Water can dissolve it, but only to a certain extent. The aqueous solution should be utilized soon after dissolving because it is unstable. It dissolves easily in ethanol. After Arnold and Bourseaux produced cyclophosphamide for the first time in 1958, its derivatives were created based on the composition and mode of action of earlier anticancer medications. Tumor immunotherapy is where it is primarily used. Chloroethylphosphamide, also known as phosphoramide mustard, is degraded by hepatic microsomal enzymes once it enters the body and has lethal effects on cancer cells due to its potent alkylating action. It significantly inhibits a variety of cancers. Due to its well-documented immunosuppressive effects, it has recently been utilized to treat a number of autoimmune illnesses and has proven to be highly effective.

Basic Information

Product name: Cyclophosphamide

CAS:50-18-0

MF: C7H15Cl2N2O2P

MW:261.09

EINECS:200-015-4

MDL No.:MFCD00005978

Melting point:41-45°C

Boiling point:336.1±52.0 °C

Density 1.33±0.1 g/cm3(Predicted)

storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Stability: Stable

Structural formula:

Quality standard

Mechanisms of action

DNA cross-linking Phosphoramide mustard, a substance with potent DNA cross-linking parcels, is created when it's metabolized in the body. DNA- DNA and DNA- protein cross-links are created by phosphorylated mustard's covalent attachment to nucleophilic bases in DNA. These cross-links help DNA from forming into its usual double-stranded structure. Cellular DNA replication and form are hampered by this DNA cross-linking damage, which eventually causes cell death.

Immunosuppression By precluding the vulnerable system's response, it has an immunosuppressive impact. It can dwindle immunoglobulin situations and drop T and B lymphocyte counts. The antigen-specific activation of lymphocytes into effector cells, as well as the antibody response to new antigens and laid-over acuity responses in the skin, can all be inhibited by Cyclophosphamide Monohydrate.

Anti-inflammatory goods have anti-inflammatory parcels that can reduce seditious responses and vulnerable-mediated injury. This is fulfilled by limiting seditious cell exertion and proliferation, reducing seditious middleman release, and precluding the activation of seditious signaling pathways.

In conclusion, it substantially inhibits excrescence cell proliferation and vulnerable system function by causing DNA cross-linking and having immunosuppressive goods. it's an extensively used immunomodulatory drug and anti-cancer drug due to these styles of action. It's significant to flashback that different treatment plans or individual dissonances may affect the precise mechanisms of action. Before using a drug, please read the directions on the marker precisely and see a croaker.

Indications

Cyclophosphamide Powder is indicated for the treatment of solid excrescences similar to neuroblastoma, ovarian cancer, bone cancer, different sarcomas, lung cancer, multiple myeloma, lymphocytic leukemia, cervical, prostate, colon, and bronchogenic cancer. It can also be used to treat autoimmune ails, juvenile nephrotic patterns, and rheumatoid arthritis.

Stability and storage

The following are the cyclophosphamide storehouse conditions

Temperature Cyclophosphamide should be kept in a room-temperature terrain between 20 °C and 25 °C( 68 °F and 77 °F). Avoid subjugating it to extremely high or low temperatures because doing so could compromise the drug's stability.

Light Because cyclophosphamide is sensitive to light, it should be kept in a vessel that's light-resistant to avoid being exposed to bright light or ultraviolet radiation. Avoid transferring the drug to transparent holders and keep it in its original package.

Moisture: Cyclophosphamide should be kept dry when being stored to help humidity buildup and high situations of moisture. To avoid humidity intrusion, make sure the drug vessel is duly sealed.

Container selection: Cyclophosphamide is frequently stored in tightly sealed plastic or glass holders. To help oxidation and impurity of the drug when storing it, ensure sure the package is secure and that the vessel is well sealed.

Position for storehouse: Keep cyclophosphamide out of the sun, down from heat sources, and down from open dears. also, keep the medicine out of children's reach to avoid accidents or unintentional input.

Please be apprehensive that before using Cyclophosphamide, it's pivotal to completely read the drug's directions and seek advice from your croaker or druggist regarding proper storehouse practices.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Payment Term

Why Choose Xi'an Yihui?

Customer feedback

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Xi'an Yihui Factory & Warehouse

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional Cyclophosphamide Powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Cyclophosphamide, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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