Remdesivir Powder
CAS No.: 1809249-37-3
Assay: 99%
Brand: YIHUI
Packing: 1kg/bag;25kg/drum
Supply Ability:5000kg per month
Delivery Time: Delivery within 3 days from warehouse after payment or order
Shelf Life: Two years
Payment: T/T, LC or DA
Origin: China
Can’t sell to individuals
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Product Introduction
Remdesivir powder Suppliers
Xi'an Yihui Company is a professional manufacturer of Remdesivir API. We can generate remdesivir with a 99.9% content.It can be employed in drug or health care particulars, meet USP, BP, EP, CP norms. We can offer you products of the loftiest quality at the most competitive rates. Your stylish option for an estimable remdesivir powder supplier isXi'an Yihui Company!
What is Remdesivir powder?
Remdesivir API is a broad- diapason antiviral medicine that can be used to treat colorful viral infections, including respiratory syncytial contagion( RSV), Ebola contagion, Crimean Congo hemorrhagic fever contagion, and coronavirus. it's a white to nearly white crystalline powder. The molecular formula is C27H35N6O8P, with a molecular weight of602.6 grams/ operative, and the CAS number is 1809249-37-3. it has a low solubility in water. Remdesivir belongs to nucleoside analogues and has the capability to bed into the viral RNA chain to intrude with its replication. It can be converted into active metabolites through phosphorylation responses, inhibiting the exertion of viral RNA dependent RNA polymerase.
Remdesivir was firstly developed by Gilead lores for the treatment of Ebola contagion infections. latterly, due to its broad- diapason antiviral goods on other contagions, it sparked interest in other viral infections. After the COVID- 19 outbreak, it came a largely anticipated medicine seeker. Clinical trials have shown that in some cases, it can dock sanitarium stay and recovery time, and give a certain degree of efficacity. presently, it has attained exigency use authorization from some countries and is being used encyclopedically for the treatment of COVID- 19.
Basic Information
Product name: Remdesivir (GS-5734)
Chemical name: 2-ethylbutyl ((S)-(((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate
CAS No.: 1809249-37-3
MF:C27H35N6O8P
MW:602.58
EINECS:210-629-4
MDL No.:MFCD31657351
storage temp.: Sealed preservation at room temperature
Stability: Stable
Structural formula:
Quality standard
Items | Specifications | Results |
Appearance | White to off-white powder | white powder |
Identification | HPLC:The retention time of main peak of test product is consistent with that of standard | Complies |
Solubility | Insoluble in water and soluble in methanol | Complies |
Specific Rotation | -18° ~-25° | -21.10° |
Water content | NMT 1.0% | 0.20% |
Related Substance | Any unspecific individual impurity NMT 0.1% | 0.07% |
Total impurity NMT 0.3% | 0.13% | |
Purity (HPLC) | NLT 99.7% | 99.87% |
Residue of solvents | Methylene dichloride NMT 0.06% | 0.007% |
Methanol NMT 0.3% | 0.039% | |
Acetonitrile NMT 0.041% | N.D. | |
Ethyl acetate NMT 0.5% | N.D. | |
Acetone NMT 0.5% | N.D. | |
Isopropyl Ether NMT 0.5% | N.D. | |
Isopropyl acetate NMT 0.5% | N.D. | |
2,2-dimethoxypropane NMT 0.1% | N.D. | |
Tetrahydrofuran NMT 0.072% | N.D. | |
Isomer | RD NMT 0.20% | N.D. |
SD NMT 0.20% | N.D. | |
RL NMT 0.20% | N.D. | |
Residue on ignition | NMT 0.2% | 0.10% |
Heavy metals | NMT 10ppm | Complies |
Microbial Limit | Total aerobic bacteria NMT 100cfu/g | <10cfu/g |
Total number of moulds and yeasts NMT 100cfu/g | <10cfu/g | |
Bacterial Endotoxin | NMT 0.5EU/mg | Complies |
Assay(HPLC) | 98.0%~102.0% | 99.4% |
Conclusion | The product conforms to the above specifications | |
Storage | Sealed preservation at room temperature |
Function &Application
Remdesivir API is a broad- diapason antiviral medicine that primarily functions by inhibiting the replication and spread of contagions. Then are some crucial points about its function
Interfering with viral RNA chain replication it's a nucleoside analogue that can fit into viral RNA chains, dismembering the contagion replication process. It can bind with viral RNA-dependent RNA polymerase and help the conflation of new nucleic acid chains, thereby inhibiting contagion replication.
Inhibiting contagion proliferation By inhibiting the exertion of viral RNA polymerase, it can block the replication and recap process of contagion genomes, reducing contagion product and proliferation.
Broaddiapason antiviral effect it has exertion against multiple contagions, including respiratory syncytial contagion( RSV), Ebola contagion, Crimean- Congo hemorrhagic fever contagion, and coronaviruses. Its medium allows it to potentially work in colorful types of viral infections.
Shortening hospitalization and recovery time Clinical trials have shown that it can dock hospitalization and recovery time in some cases. It can palliate symptoms and inflexibility of viral infections, helping cases recover briskly.
It should be noted that the specific functions may vary depending on factors such as contagion type, operation system, and patient condition. Before using Remdesivir or any other drug, consult a healthcare professional for accurate advice and guidance.
Storage
The storage requirements for Remdesivir API are as follows:
Storage temperature it should be stored in refrigerated conditions between 2 °C to 8 °C( 36 °F to 46 °F). ensure that the drug isn't exposed to exorbitantly high or low temperatures.
Light perceptivity it's sensitive to light, so it should be kept down from the direct sun. Store it in its original packaging to minimize exposure to light.
Package integrity ensures that the original packaging of Remdesivir is complete to help humidity or impurity of the drug.
It's important to note that these are general storehouse conditions, and specific guidelines may vary depending on the manufacturer, batch, and regulations of the country region. Before using Remdesivir, please relate to the drug's package insert or consult healthcare professionals to ensure proper storehouse and operation.
Current Status
Remdesivir powder is a nucleotide analog prodrug. In vitro trials and beast models have shown that Remdesivir inhibits RNA-dependent RNA polymerase( RdRp), which suppresses colorful coronaviruses, including Severe Acute Respiratory Syndrome( SARS), Middle East Respiratory Syndrome( MERS), Ebola contagion, and other coronaviruses. In vitro cell trials have demonstrated that the half-minimal effective attention( EC50) of Remdesivir for the new coronavirus is0.77 μmol · L- 1. still, Remdesivir has not been approved for marketing in any country, and its efficacity and safety haven't been verified through Phase III clinical trials. Clinical trials for Ebola contagion only reached Phase II.
Packing & Shipping
Quilting 1kg/ antipode bag; 5kg/ tinderbox; 25kg/ fiber barrel; or packing as your request.
CustomizationCustomized totem; tailored packaging; Graphic customization
Shipping:
Item | Quantity | ETA time | Shipping Method |
By Courier | ≤50kg | 7-15days | Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air | 50kg~200kg | 3-5days | Fast and cheap |
By Sea | Large quantity | 20-35days | Cheapest way |
Payment Term
Why Choose Xi'an Yihui?
Customer feedback
Xi'an Yihui certificates
Xi'an Yihui Factory & Warehouse
Our Advantage
Rich experience: we have 13 Years of professional experience;
Customers all over the world: sell to more than 100 countries;
Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition, and functional food.
Price advance: low MOQ with competitive price;
Quality certification: ISO; Halal; Kosher certified
After-sales service: Professional team 7*24 hours customer service.
In conclusion
In summary, as a professional Remdesivir powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Remdesivir, pls feel free to contact us any time. we will reply you asap.
Our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937
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If you have any enquiry about quotation or cooperation, please feel free to email us at E-mailor use the following enquiry form. Our sales representative will contact you within 24 hours.Thank you for your interest in our products.