Ibuprofen API

CAS No: 15687-27-1
Appearance: white or almost white crystalline powder
Standard: USP/EP/BP
Supply Ability:100000kg per month
Purity: ≥99%
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
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Product Introduction

We supply Ibuprofen

We offer high- quality Ibuprofen API( Active Pharmaceutical Ingredient) to guests worldwide. it is a nonsteroidalanti-inflammatory medicine( NSAID) generally used to treat pain, fever, and inflammation. Our Ibuprofen is manufactured to meet strict quality norms and is suitable for use in pharmaceutical phrasings. We strive to give our guests with harmonious, dependable quality and competitive pricing.However, please do n't vacillate to communicate us, If you're in need of Ibuprofen. We're committed to meeting your requirements and exceeding your prospects.

 

What is Ibuprofen?

Ibuprofen powder is anon-steroidalanti-inflammatory analgesic. It has goodanti-inflammatory, analgesic and antipyretic goods with many adverse responses. It has been extensively used in the world and has come one of the world's best- dealing untoward medicines. It's listed as one of the three pillar products of antipyretic and analgesic medicines together with aspirin and paracetamol. In my country, it's substantially used for pain relief andanti-rheumatic goods, but not important for snap and fever reduction, far lower than paracetamol and aspirin. There are dozens of pharmaceutical companies in my country that hold blessing figures for the product of ibuprofen medications, but the vast maturity of ibuprofen deals in the domestic request are enthralled by" Fenbid" sustained- release capsules produced by Tianjin Sino- US SmithKline. it was discovered by Dr. Stewart Adams( who latterly came a professor and was awarded the Order of the British Empire) and his platoon- scientific exploration expert Colin Burrows and druggist Dr. John Nicholson. The original purpose of the exploration was to construct a" super aspirin" to gain an indispensable medicine for the treatment of rheumatoid arthritis that's as effective as aspirin but has smaller serious adverse responses. Other medicines, similar as phenylbutazone, have a high threat of agranulocytosis; corticosteroids, when used in boluses slightly advanced than the generally specified cure, carry a high threat of adrenal repression and other adverse responses similar as gastrointestinal ulcers. Adams decided to look for a medicine with good gastrointestinal forbearance, a point that's particularly important for all currentnon-steroidalanti-inflammatory medicines. Phenyl acetate medicines have aroused people's interest. Although some of these medicines have the threat of causing ulcers in canine trials, Adams realized that this miracle may be caused by the long half- life of medicine elimination. Among these medicines, there's a emulsion- ibuprofen, which has a fairly short half- life of only 2 hours. Among the indispensable medicines screened, although it is n't the most effective, it's the safest. In 1964, it came the most promising aspirin volition.

 

Basic Information

Product Name: Ibuprofen

CAS: 15687-27-1

MF:C13H18O2

MW:206.28

EINECS:239-784-6

MDL No.:MFCD00010393

Structural formula:

product-1-1

Origin: China

Delivery Time: in stock

 

Technical Specification

Item

Specification

Results

Characters

White or almost white, crystalline powder, or colourless crystals, having a slight characteristics odor

White crystalline powder, having a slight characteristics odor

Identification:

A: Melting point(℃)

B:Infrared absorption(IR)

 

75-78

Conforms to reference spectrum

 

76.1

Conforms to reference spectrum

Ibuprofen related compound C(%)

≤0.1

Not detected

Appearance of solution

Clear and colourless

Clear and colourless

Angle of option relation (°)

-0.05~+0.05

0

Heavy metals(%)

≤0.001

<0.001

Related substance[Ignore(<0.03)]:

impurity A (%)

≤0.15

Ignore

impurity J (%)

≤0.15

Not detected

impurity N (%)

≤0.15

Not detected

Another largest single impurity (%)

≤0.05

gnore

Total impurity (%)

≤0.2

gnore

impurity F(%)

≤0.1

Not detected

Loss on drying(%)

≤0.5

0.04

Residual solvents:Ethanol(ppm)

≤5000

60

Dechloromethane(ppm)

≤600

Not detected

Sulphated ash(%)

≤0.1

0.04

Assay(on dried basis,%)

97.0-103.0

99.3

Conclusion

The product is tested in accordance with BP/USP/EP. The above items meet the requirement.

Package: 1kg; 25kg or according to your demands

Storage: Preserve in tight,light-resistant containers in cool place

Shelf Life:Powder: 2 years

 

Function

Ibuprofen API serves several key functions, primarily due to its properties as a nonsteroidal anti-inflammatory drug (NSAID). Here are its main functions:

Pain Relief: It alleviates mild to moderate pain from various sources, including headaches, menstrual cramps, dental pain, and muscle aches.

Anti-Inflammatory Action: Ibuprofen reduces inflammation, making it useful for conditions like arthritis, sprains, and strains.

Antipyretic: It effectively lowers fever, helping to manage elevated body temperature due to infections or illnesses.

Postoperative Pain Management: It helps in managing pain following surgical procedures, providing relief and improving comfort during recovery.

Chronic Pain Management: In some cases, it is used to manage chronic pain conditions, such as osteoarthritis and rheumatoid arthritis.

 

Application

Ibuprofen powder is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for various purposes, including:

Pain Relief: Effective for mild to moderate pain, such as headaches, toothaches, menstrual cramps, and muscle aches.

Inflammation Reduction: Often used to decrease inflammation associated with conditions like arthritis, strains, or sprains.

Fever Reduction: Helps lower fever in both adults and children.

Postoperative Pain Management: Frequently used to manage pain after surgical procedures.

Chronic Pain Conditions: Sometimes prescribed for chronic pain conditions, such as osteoarthritis and rheumatoid arthritis.

Dosage and Considerations: It's important to follow dosage guidelines and consult a healthcare provider, especially for long-term use or if you have underlying health conditions. Potential side effects include gastrointestinal issues, kidney damage, and increased risk of heart problems with prolonged use.

 

Side effect

Ibuprofen can cause several side effects, though not everyone experiences them. Common side effects include:

1. Gastrointestinal Issues:

Stomach pain

Nausea

Vomiting

Diarrhea

Heartburn

Ulcers or bleeding in the stomach

 

2.Kidney Problems:

Reduced kidney function

Increased blood pressure

 

3.Cardiovascular Risks:

Increased risk of heart attack or stroke, especially with long-term use or in high doses.

 

4.Allergic Reactions:

Rash

Itching

Swelling (especially of the face/tongue/throat)

Difficulty breathing

 

5.Liver Damage:

Rare but possible, characterized by symptoms like jaundice (yellowing of skin/eyes), dark urine, or severe fatigue.

 

6.Central Nervous System Effects:

Dizziness

Headache

Tinnitus (ringing in the ears)

It's important to use ibuprofen as directed and consult a healthcare professional if you experience any severe or persistent side effects.

 

Packing & Shipping

Packing:

1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization:

l Customized logo

l Customized packaging

l Graphic customization

Shipping:

By Courier; By Air or By Sea, according to your demands

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Payment Term

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Contact Yihui company

as a professional Ibuprofen API manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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