We supply Fexofenadine Hydrochloride API

Fexofenadine Hydrochloride API is a high- quality medicine component that we offer. It's a potent antihistamine used to treat colorful seasonal disinclinations, similar as hay fever, habitual urticaria, and other affiliated conditions. This API meets the loftiest quality norms and is extensively used in the pharmaceutical assiduity. Our Fexofenadine Hydrochloride is manufactured under strict GMP guidelines to insure the chastity and efficacity of the product. Our product is available in colorful packaging options and can be customized to meet the specific requirements of our guests. communicate us to learn further about our Fexofenadine HCL.

What is Fexofenadine Hydrochloride API?

Fexofenadine HCL API is a drug used to treat symptoms associated with disinclinations. It belongs to the class of medicines known as antihistamines and workshop by blocking the action of histamine, a chemical in the body that causes mislike symptoms similar as itching, sneezing, and watery nose.

This API is generally used to treat symptoms associated with seasonal disinclinations, similar as hay fever or antipathetic rhinitis, as well as habitual urticaria. It's available in tablet form and can be taken orally with or without food.

In terms of safety, it has been set up to be generally well- permitted by cases, with mild side effects similar as headache and doziness reported in some cases. It isn't recommended for use by pregnant women or individualities with severe order complaint.

Overall, it is a largely effective and extensively specified drug for the treatment of mislike symptoms. Its vacuity in tablet form makes it accessible for cases to use, while its safety profile makes it a favored choice for numerous healthcare providers.

Basic Information

Product Name: Fexofenadine Hydrochloride

CAS: 153439-40-8

MF:C32H40ClNO4

MW:538.13

EINECS:604-906-2

MDL No.:MFCD08064193

Structural formula:

Application: Antihistaminic; Antihistamine

Origin: China

Delivery Time: in stock

Technical Specification

Package: 1kg;25kg; or according to your demands

Storage conditions:2-8℃, protected from light and moisture, sealed and dry

Transportation conditions: 2-8 ℃ transportation

Shelf Life:24 months

Application

Fexofenadine hydrochloride API, generally known as fexofenadine, is primarily employed in the treatment of antipathetic conditions, particularly antipathetic rhinitis( hay fever) and habitual idiopathic urticaria( hives) in humans. Then’s a detailed look at its application and application

Antihistamine: Fexofenadine belongs to the alternate- generation antihistamine class. It works by widely envenoming the histamine H1 receptors in the body, thereby reducing the effects of histamine release during antipathetic responses.

Antipathetic Rhinitis: It's extensively specified for the relief of symptoms associated with antipathetic rhinitis, including sneezing, watery nose, itchy or watery eyes, and nasal traffic. Fexofenadine helps palliate these symptoms without causing significant sedation, unlike some first- generation antihistamines.

habitual Idiopathic Urticaria: Fexofenadine is also effective in the treatment of habitual idiopathic urticaria, a condition characterized by intermittent occurrences of hives or welts without a known cause. It helps relieve itching and reduces the circumstance of hives.

Medium of Action: Fexofenadine's medium involves blocking histamine receptors in supplemental apkins, which prevents histamine- convinced antipathetic responses. It doesn't readily cross the blood- brain hedge, which contributes to itsnon-sedating nature.

Lozenge and Administration: The lozenge of fexofenadine hydrochloride varies depending on the age, weight, and specific condition of the case. It's generally administered orally in tablet or liquid suspense form. Lozenge adaptations may be necessary in cases with disabled renal function.

Safety and Side effects: Fexofenadine is generally well- permitted with a low prevalence of sedation compared to aged antihistamines. Common side effects may include headache, doziness( however less common), and gastrointestinal disturbances like nausea or diarrhea.

Regulatory blessing: Fexofenadine hydrochloride has been approved by nonsupervisory agencies similar as the FDA( Food and Drug Administration) in the United States and the EMA( European Medicines Agency) in Europe for its indicated uses in antipathetic conditions.

Pharmacological effects

Fexofenadine HCL API is an H1 receptor antagonist. Both in vivo and in vitro trials have shown that it can inhibit the release of histamine from mast cells and is more picky than fexofenadine. It can significantly reduce the expression of adhesion motes between epithelial cells and reduce the release of interleukin- 6 in a attention-dependent manner; it can significantly reduce the release of interleukin- 8, granulocyte- macrophage colony- stimulating factor and answerable adhesion motes convinced by eosinophils. Release; and can significantly inhibit histamine- convinced wheals and flushing. Because it doesn't fluently access the blood- brain hedge, it has no opiate or anticholinergic effects.

Side effect

Because fexofenadine hydrochloride doesn't pass the blood- brain hedge, there are no side effects similar as doziness and doziness. Common side effects at clinically recommended boluses include dry mouth, dizziness, occasional headaches and nausea, which can vanish snappily after stopping the medicine. Because it has high selectivity for H1 receptors and little effect on H2 receptors, it doesn't affect gastric acid stashing like antihistamineanti-allergic medicines, so it'll not beget weight gain. It also has no anticholinergic effect and α1- receptor blocking effect.

Drug relations

1. still, the efficacity of this medicine will be reduced, If combined with antacids containing aluminum and magnesium. This drug shouldn't be used before or after taking antacids, or 2 hours piecemeal.

2. still, apple juice, grapefruit juice, If combined withfood., the bioavailability of this medicine will be reduced and the efficacity will be weakened, so it isn't suitable for combined use.

3. When combined with erythromycin and ketoconazole, the blood attention of this medicine will increase. It'll not affect the pharmacokinetics and QT interval of erythromycin and ketoconazole, nor will it increase the prevalence of adverse responses.

4. Combined use with medicines that can protract the QT interval similar as droperidol may increase cardiotoxicity.

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In summary, as a professional Fexofenadine Hydrochloride API manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Fexofenadine HCL API, pls feel free to contact us any time. we will reply you asap.

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E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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