What is Posaconazole?

Posaconazole powder is a chemical raw material. Its molecular formula is C37H42F2N8O4, its relative molecular mass is700.8 g/ spook, and its CAS number is 171228-49-2.

Its chemical structure includes multiple structural units similar as triazole ring, benzofuran ring, sweet ring, oxime, and carboxylic acid. The patch has stereoisomers substantially caused by two chiral centers. It's a white or nearly white powder. It's undoable in water, answerable in ethanol, acetone, dichloromethane and methanol.

After oral or intravenous administration, Posaconazole API undergoes metabolism in the liver to produce active metabolites with stronger antifungal exertion. The metabolic products of the medicine are substantially excreted through the feathers, and incompletely excreted through the liver and corrosiveness tubes.

It's a broad-diapason antifungal medicine that exerts its fungicidal effect by snooping with the conflation of fungal cell walls and membranes. It has high- effectiveness fungicidal exertion against colorful fungi and is extensively used to treat fungal infections similar as oral candidiasis, pulmonary aspergillosis, cryptococcosis, and mucormycosis.

It was developed by Pfizer. The following is its development history:

In 1998, Pfizer began to develop it.

In 2003, it entered the clinical trial stage.

In 2006, it was approved by the FDA for oral suspense form for the treatment of refractory fungal infections.

In 2013, it was approved by the European Medicines Agency( EMA) to treat infections that are ineffective or intolerable to other antifungal medicines, including aspergillosis, candida infection and Cryptococcosis.

In 2014, it was approved by the FDA.

It has gone through numerous clinical trials, including treatment trials for pulmonary aspergillosis, Cryptococcosis, mycoplasma pneumonia and other infections. In these clinical trials, it has shown good antifungal exertion and forbearance. It has come one of the important medicines for treating refractory fungal infections and precluding infections.

Basic Information

Quality standard

Stability & Storage

Posaconazole powder is a stable substance with good thermal stability and light stability, which can be stored for many years under normal storage conditions. It is relatively stable under acidic conditions, but unstable under alkaline conditions. it will undergo degradation inalkaline conditions. In addition, it is also unstable in water. so it should be avoided from direct exposure to water or high humidity environments. During the preparation process, care should be taken to prevent contact with factors such as oxidants, reducing agents and metal ions to avoid affecting its stability. Before use, carefully check the store and use according to the instructions to ensure its quality and effectiveness.

The storage conditions should meet the following requirements:

Temperature Posaconazole price should be stored in an terrain of 15- 30 degrees Celsius, avoiding exorbitantly high or low temperatures, while also precluding direct exposure to UV radiation.

moisture It should be stored in a dry and breezy place, avoiding moistness and high moisture surroundings.

Packaging It should be stored tightly sealed, keeping the packaging complete and undamaged.

When storing, avoid contact with oxidants, reducers, essence ions, and other substances to help gratuitous chemical responses and affect the quality and effectiveness of the medicine.

In summary, when storing, care should be taken to avoid the impact of extreme temperature, moisture and other environmental factors to insure its quality and stability.

Packing & Shipping

Quilting 1kg/ antipode bag; 5kg/ tinderbox; 25kg/ fiber barrel; or packing as your request.

CustomizationCustomized totem; tailored packaging; Graphic customization

Shipping:

Payment Term

Why Choose Xi'an Yihui?

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Xi'an Yihui Factory & Warehouse

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition, and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, Xi'an Yihui company as a professional Posaconazole powder manufacturer has strong technical strength and advanced production equipment and is committed to providing customers with high-quality, efficient and reliable drug raw materials. if you need it, pls feel free to contact us at any time. we will reply you ASAP.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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