Estradiol Powder

Product name: β-Estradiol
CAS No.: 50-28-2
MOQ: 100G
Assay: 99%
Package:100g/bag;500g/bag;1kg/bag;5kg/bag
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Supply Ability: 500kg per month
Delivery Time:in stock
Shelf Life: Two years
Payment: T/T, LC or DA
Can’t sell to individuals
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Product Introduction

What is Estradiol Powder?

Estradiol Powder is a white or out-white or unformed powder that's answerable in dioxane and acetone, slightly answerable in ethanol, and undoable in water. β- Estradiol is an intermediate between estrone and estriol and belongs to the class of estrogenic medicines. It can be used to treat functional uterine bleeding, primary amenorrhea, menopausal pattern, and prostate cancer. It promotes and regulates the normal growth of womanish reproductive organs and secondary sexual characteristics. It stimulates the development and growth of mammary tubes and aids in localization. It can also be used in biochemical exploration.

Basic Information

Product Name:BETA-ESTRADIOL-16,16,17-D3; 17BETA-ESTRADIOL-16,16,17-D3; 17beta-Estradiol; 3,17beta-Dihydroxy-1,3,5(10)-estratriene; Dihydrofolliculin; Estradiol

CAS:50-28-2

MF: C18H24O2

MW:272.39

EINECS:200-023-8

Melting point:178-179 °C(lit.)

storage temp. room temp

Purity:99%

Stability: Stable for 2 years

Application: medicine grade or used for research.

Packing:As per your request

Structural formula:

50-28-2.webp

Quality standard

TEST

ACCEPTANCE CRITERIONS

RESULTS

Identification

Ultraviolet Absorption

Positive


Infrared Absorption

Positive

Characteristics

White or creamy white, crystalline powder

conform

Melting point

173 ~ 179℃

175~ 179℃

Specific rotation

﹢76°~﹢83°

﹢78°

Water

≤3.5%

Pass

Assay

97 .0~ 103.0%

99.25%

Loss on drying

≤0.5%

0.15%

Related substances

Any individual impurity ≤0.5%

Total impurities ≤1.0%

Pass

Pass

Residual solvents

ethanol ≤0.5%

Pass

Conclusion

This batch complies with USP standard

Function and application

In biochemical research, it is used as a class of estrogenic drugs.

  • Beta Estradiol is used as an estrogenic medicine for the treatment of functional uterine bleeding, primary amenorrhea, menopausal pattern, and prostate cancer. It promotes and regulates the normal development of womanish reproductive organs and secondary sexual characteristics. It stimulates the development and proliferation of mammary tubes. still, at advanced boluses, it can inhibit the release of prolactin from the anterior pituitary, reducing milk stashing. It can also be used for lactation repression. Side goods may include nausea, puking, and inordinate endometrial growth leading to bleeding. It should be used with caution in individualities with bloodied liver or order function. It should be avoided on the bone, external genitalia, and vaginal mucosa.

  • Its applications include being an intermediate for estradiol valerate and estradiol benzoate.


Biosynthesis

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In humans and other advanced creatures, steroid hormones are deduced from cholesterol. Cholesterol undergoes oxidation and side- chain fractionalization to produce pregnenolone, which is farther converted into progesterone, 17α- hydroxyprogesterone, and eventually a crucial intermediate, androstenedione. Some of the androstenedione is converted into testosterone, which is also seasoned by aromatase into estradiol. Another pathway involves aromatization of androstenedione to estrone, which is latterly converted to estradiol. Granulosa cells, theca cells, the placenta, the adrenal cortex, and interstitial cells in the testes can all produce estradiol. In women of reproductive age, estradiol is primarily generated from androstenedione produced by the ovarian theca cells via metabolism in granulosa cells. Extra-gonadal organs and apkins, similar as adipocytes, also produce estradiol, indeed after menopause. Although estradiol doesn't fluently cross the blood- brain hedge from the rotation, it's one of the two active metabolites of testosterone( the other being dihydrotestosterone) and can thus be synthesized in the brain.

In plants, the synthesis of estradiol has been found in soybeans.

Stability and storage

  • Storage temperature: Estradiol Powder should be stored at room temperature, typically between 15°C and 30°C. Avoid exposure to excessively high or low temperatures, and do not freeze.

  • Packaging and sealing: It should be stored in well-sealed containers to prevent moisture and light exposure. Avoid direct sunlight and keep it dry.

  • pH environment: The stability of it is pH-dependent. The optimal pH range is between 2 and 5. Ensure that the solution has an appropriate and stable pH value.

  • Avoid oxidation: Beta Estradiol is susceptible to oxidation, so measures should be taken to minimize its exposure to oxygen. During storage, you can protect the stability of the medication by ensuring tight container sealing or using antioxidants.

  • Avoid impact: Avoid severe vibration or impact on the container to prevent drug decomposition and degradation.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Item

Quantity

ETA time

Shipping Method

By Courier

≤50kg

7-15days

Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air

50kg~200kg

3-5days

Fast and cheap

By Sea

Large quantity

20-35days

Cheapest way

Lead time: Within 3 workdays after receiving payment.

Payment Term

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Why Choose Xi'an Yihui?

Customer feedback

 Customer Comments.webp

Xi'an Yihui certificates

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Xi'an Yihui Factory & Warehouse

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional Estradiol Powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Beta Estradiol stand out in the market competition and win more customer trust and support. if you need Beta Estradiol Powder CAS 50-28-2, pls feel free to contact us any time. we will reply to you ASAP.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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