What is Doxorubicin Hydrochloride powder?

Doxorubicin Hydrochloride powder, its chemical name is 10-(( 3- amino-- L- lyxopyranosyl) oxy).-(hydroxymethyl) Hydrochloride of 1- methoxy -5,12-naphthacenedione. Other names for it include Doxorubicin hcl; DRIAMYCIN HCL and DRIAMYCIN HYDROCHLORIDE. An orange-red lyophilized powder known as pure Doxorubicin has a melting point of 216 °C and is water answerable. Doxorubicin, generally appertained to as Taxotere/ ADM is constantly used in clinical chemotherapy to treat cancer in people. It's a member of the class of semi-synthetic anthracycline antibiotics. Doxorubicin has the same capability to fit with cellular DNA as doxorubicin and other anthracyclines, which can impact DNA conflation. multitudinous cancers, including hematologic malice, solid excrescences, and soft towel sarcomas, are frequently treated with it. It is frequently used with other medications to treat cancer in human medical practice.

Basic Information

Product name: Doxorubicin Hydrochloride

CAS:25316-40-9

MF: C27H30ClNO11

MW:579.98

EINECS:246-818-3

MDL No.:MFCD00077757

Melting point:216 °C (dec.)(lit.)

alpha D20 +248±2° (c = 0.1 in methanol)

storage temp. 2-8°C

Stability: Stable

Structural formula:

Quality standard

Pharmacological action

Doxorubicin Hydrochloride acts pharmacologically by intercalating and preventing the interface between DNA and macromolecular biosynthesis, hence preventing DNA topoisomerase II from functioning. Doxorubicin interferes with DNA chain replication by preventing the closing of DNA's double helix. it can affect transcriptionally active chromatin through intercalation, altering histones. The findings show that the epigenome, transcriptome, and DNA damage response in cells exposed to doxorubicin are not under control.

Function

Doxorubicin Hydrochloride is a chemotherapeutic medicine extensively used in cancer treatment. It belongs to the anthracycline class of antitumor antibiotics and has multiple functions and mechanisms of action. The primary duties consist of:

The antitumor effect it has an antitumor impact by interacting with cellular DNA and snooping with DNA replication and recap, which help cancer cells from proliferating and dividing.

The cytotoxic effect has a cytotoxic impact in that it kills cancer cells by converting oxidative stress and reactive oxygen species, which damage the cell membrane, mitochondria, and other cellular factors.

The anti-angiogenic effect has an anti-angiogenic impact by precluding the creation of blood vessels girding excrescences, cutting off their blood force and precluding the spread of the excrescences.

The immunomodulatory effect may regulate the vulnerable system, strengthening the body's defenses against cancer cells.

Doxorubicin Hydrochloride has a number of venom and side goods, including as cardiotoxicity, hematological repression, and gastrointestinal problems, which should be taken into consideration. Strict adherence to the croaker's instructions and close observation of the case's health and medicine forbearance are needed while it's being used.

Application

Doxorubicin Hydrochloride is a chemotherapeutic medicine extensively used in the treatment of cancer. It's employed for colorful types of nasty excrescences. Then are some common areas of operation

bone Cancer it's occasionally used in combination with other anticancer specifics to treat advanced or metastatic bone cancer.

Hodgkin's carcinoma and non-Hodgkin's carcinoma are both first- line treatments for it.

Non-small cell lung cancer can be treated with it, particularly when combined with other chemotherapy treatments.

it is constantly used in confluence with other specifics throughout the induction and conservation ages of acute myeloid leukemia treatment.

it is used to treat epithelial ovarian cancer, especially when it has spread or reenacted.

it is one of the introductory treatment options for osteosarcoma and is constantly combined with other specifics following radiation remedy and surgery.

These are but many typical uses for doxorubicin hydrochloride. The case's health and the croaker's advice will determine the precise dosing and administration. It's pivotal to heed the advice of the healthcare provider and nearly cover the case's physical health and medicine toxin.

Stability and storage

The following are the stability and storage requirements for doxorubicin hydrochloride:

• Doxorubicin Hydrochloride powder should be kept in a refrigerator between 2 and 8 degrees Celsius for storage. Avoid freezing the medication because doing so could render it useless.

• Packaging and protection: Glass, plastic, or ampoules are frequently used to package and protect medications. Seal and safeguard the packaging appropriately in accordance with the manufacturer's instructions. Ensure that protective devices are intact to avoid contamination and oxidation.

• It should not be exposed to bright light since it is photosensitive. When storing, use opaque packing or containers and keep the items in a cold, dry place that is shaded.

• It normally has a long stability period when stored in the proper circumstances. Please be aware, nevertheless, that the drug's stability can vary depending on the formulation, the storage environment, and the passage of time. Do not use if you see any color changes, precipitation formation, or package damage.

• Handling safety measures: To avoid skin contact and inhalation, handling doxorubicin hydrochloride should be done while using gloves and safety eyewear. Use the proper disposal techniques to dispose of garbage and drug residues.

Please be aware that the data above is solely for reference. Please read the medication instructions before using or storing Doxorubicin Hydrochloride and heed the advise of your doctor or pharmacist.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Lead time: Within 3 workdays after receiving payment.

Payment Term

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Our advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the word: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional Doxorubicin Hydrochloride powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Doxorubicin Hcl stand out in the market competition and win more customer trust and support. if you need Doxorubicin api, pls feel free to contact us any time. we will reply you asap.

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