What is Calcitriol powder?

Calcitriol powder, also known as 1,25- dihydroxycholecalciferol or 1,25- dihydroxy vitamin D3, is the active form of vitamin D and a hormone in the body that plays an important part in regulating blood calcium and phosphate situations. It increases calcium ion immersion in the intestine, thereby raising blood calcium situations, and also increases calcium release from bone to raise blood calcium situations. This medium was first reported by Michael F. Holick in 1971. It frequently acts by binding to the vitamin D receptor( VDR), similar to the ligand-receptor complex formed by the receptor in the cytoplasm of intestinal epithelial cells, which is transferred to the nexus as a recap factor that promotes the expression of calcium-binding proteins, adding active calcium ion transport and immersion.

At the same time, to maintain electrical impartiality, anions also need to be transported, substantially by absorbing inorganic phosphate ions, so it promotes phosphate immersion as well. Clinically, it can be used to treat hypocalcemia, hypoparathyroidism( in grown-ups), osteomalacia, rickets( in babies and youthful children), habitual order complaint, renal osteodystrophy, and osteoporosis, and to help corticosteroid- convinced osteoporosis. It's one of the most important active metabolites of vitamin- D3, which is generally formed in the feathers. In recent times, it has been set up that it can also be produced outside the feathers, and it has been proven to live in the placenta, monocytes, macrophages, excrescence cells, lymph bumps of cases with sarcoidosis, and keratinocytes due to the presence of 1α- hydroxylase. The precursor of calcitriol is  25-hydroxycholecalciferol ( alfacalcidol). Calcitriol has functions similar as promoting calcium immersion in the small intestine and regulating inorganic swab transport in bones.

Basic Information

Product name: Calcitriol

CAS No.: 32222-06-3

MF: C27H44O3

MW:416.64

EINECS:250-963-8

MDL No.:MFCD00867079

Used: research and pharma grade

Stability: Stable

Structural formula:

Quality standard

Function & Application

Calcitriol API functions as follows:

• Promoting Calcium Absorption: it increases the immersion of calcium ions in the intestine, helping to elevate the position of calcium in the blood. By binding with receptors in cells, it promotes the expression of calcium-binding protein recap factors, thereby adding active transport of calcium ions by cells and enhancing the position of calcium immersion.

• Regulating Bone Metabolism: it can increase the release of calcium from bones, raising the position of calcium in the blood. By binding with receptors in bone cells, it promotes bone redoing and calcium transport, regulating the health of bones.

In summary, Calcitriol plays an important part in regulating blood calcium and phosphate attention, promoting the immersion of calcium and phosphate, and regulating bone metabolism. It's one of the crucial hormones for maintaining bone health and calcium-phosphate balance.

The applications of Calcitriol API are as follows

• Treatment of Hypocalcemia: it can be used to treat hypocalcemia caused by shy salutary input or immersion diseases due to Vitamin D insufficiency

• Treatment of Osteoporosis: it can be used to treat osteoporosis in grown-ups and senior. Promoting the immersion of calcium and phosphate in the intestine, it increases bone viscosity and reduces the threat of fractures.

• Treatment of Renal Osteodystrophy: In cases with habitual order complaints, renal dysfunction can lead to metabolic diseases of bones. it can help regulate blood calcium and phosphate situations and help treat renal osteodystrophy.

• Treatment of Hypoparathyroidism: Hypoparathyroidism refers to the body's incapability to cache enough PTH, leading to dropped blood calcium. It can replace PTH and increase blood calcium situations

• Treatment of Inflammatory Bowel Disease: Cases with seditious bowel complaints ( similar as Crohn's complaint and ulcerative colitis) frequently have intestinal immersion diseases, leading to calcium and Vitamin D insufficiency. it can be used to correct these scarcities and ameliorate bone health.

Storage

The storage conditions for Calcitriol powder are typically as follows:

• Temperature: Store it at refrigerated temperatures, between 2°C and 8°C. Avoid exposure to high temperatures or freezing environments.

• Light: it should be protected from exposure to strong light or sunlight, as light can reduce its stability. Therefore, the medication should be stored in a dark place.

• Packaging: Keep it in its original packaging, intact, to prevent oxygen, moisture, or other external factors from affecting it.

• Moisture protection: It is advisable to minimize moisture exposure for Calcitriol. Consider using a sealed container or desiccant when storing it to reduce the risk of moisture damage.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Payment Term

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional Calcitriol powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply to you ASAP.

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