What is Camostat Mesilate Powder?

Camostat mesilate powder is a medication that is used primarily in Japan to treat various medical conditions. It is derived from a naturally occurring small molecule called camostat, which has been modified into its mesylate form for therapeutic purposes.

Camostat mesilate has several mechanisms of action. It is known to act as a serine protease inhibitor, which means it can inhibit the activity of certain enzymes involved in various physiological processes. In particular, it has been found to inhibit the activity of the enzyme called TMPRSS2 (transmembrane serine protease 2), which plays a role in viral entry.

Basic Information

Product Name: camostat mesilate

CAS: 59721-29-8

MF:C21H26N4O8S

MW:494.52

EINECS:694-565-6

MDL No.:MFCD00941410

Purity: 99%

Package: 10g;100g;1KG ;5kg

Used: Pharma grade &Lab research

Stability: Stable

Structural formula:

Specifications and Parameters:

Chemical Composition:

Role and Function:

Camostat Mesilate is a force to be reckoned with in repressing proteolytic catalysts, especially the transmembrane serine protease TMPRSS2. Generally perceived for its restorative potential, it assumes a vital part in different clinical applications. The essential capabilities include:

• Inflammation-relieving Properties: It mitigates aggravation by smothering the enactment of proteases associated with provocative cycles.

• Antiviral Movement: It exhibits antiviral impacts by restraining the movement of TMPRSS2, a protease vital for the section of certain infections into have cells.

• Potential for Respiratory Infections: Camostat mesilate powder shows guarantee in the treatment of respiratory sicknesses, particularly those brought about by infections requiring TMPRSS2 for cell section.

• Research Applications: It is a useful research tool that helps researchers understand how protease activity works and create targeted therapies.

Synthesis Process:

59721-29-8 is synthesized through a meticulous process involving precise chemical reactions. The key steps include:

1. Esterification: Acylation of a key intermediate with a suitable acid.

2. Mesylation: Introduction of the mesyl group to enhance stability.

3. Crystallization: Purification through crystallization to achieve high purity.

Quality Standards:

Yihui upholds the highest quality standards in the production of the product. Each batch undergoes rigorous testing to ensure compliance with international norms. Quality control measures include:

• High-Performance Liquid Chromatography (HPLC): Ensures assay meets or exceeds 99.5%.

• Microbial Limits Testing: Confirms compliance with established standards.

• Heavy Metal Analysis: Guarantees levels below permissible limits.

• Appearance: Crystalline white or nearly white powder

• Identification: Ought to agree with the reference standard

• Misfortune on drying: Not more than 0.5%

• Heavy metals: Not more than 10 parts per million

• Assay: 98.0% to 102.0%

• Absolute pollutants: On a dried basis, no more than 0.3 percent

Application Fields:

59721-29-8 finds applications across diverse industries:

• Pharmaceuticals: Vital in the formulation of antiviral and anti-inflammatory medications.

• Biotechnology: Used in research and development of protease inhibitors.

• Healthcare: Potential in respiratory disease treatments.

• Pancreatic issues: The product has been utilized in the therapy of intense and persistent pancreatitis, as well as pancreatic malignant growth. It has been displayed to diminish aggravation and safeguard against pancreatic harm.

• Diseases of the lungs: It has been researched for its likely use in treating respiratory illnesses like persistent obstructive pneumonic sickness (COPD) and asthma. It has been found to lessen aviation route aggravation and further develop lung capability.

• COVID-19: It has acquired consideration during the Coronavirus pandemic because of its expected inhibitory impacts on the SARS-CoV-2 infection. It has been demonstrated to inhibit the transmembrane protease serine 2 (TMPRSS2) activity, which prevents the virus from entering host cells.

• Hepatic issues: It has additionally been researched for its possible use in treating liver illnesses like non-alcoholic greasy liver sickness (NAFLD) and liver fibrosis. Diminishing aggravation and fibrosis in the liver has been found.

  
  

Contact Us

Yihui, as a trusted Camostat mesilate powder manufacturer, adheres to international standards, ensuring product quality. With ISO, Kosher, Halal certifications, we guarantee excellence. For inquiries or purchases, contact us at sales@yihuipharm.com.

In conclusion, the product stands as a testament to Yihui's commitment to excellence, offering a versatile and potent solution in the ever-evolving landscape of pharmaceuticals and research.