Capecitabine API
Package: 1kg;25kg
Origin: China
Supply Ability: 10000kg per month
Sample Available: Yes
Shelf Life: Two years
Payment: T/T, LC or DA
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Third Party Test: available
Plant Audition: available
Can’t sell to individuals
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
What is Capecitabine API?
Capecitabine powder is a prodrug that's precipitously converted into the active metabolite 5- fluorouracil( 5- FU) in the body by the action of multiple enzymes to ply its effect. Capecitabine API is a solid substance that exists as a white or nearly white crystalline powder. The CAS number for it is 154361-50-9. It's slightly answerable in water and readily answerable in alcohol( ethanol).
The developmental history of it is as follows:
Early 1980s: It was first synthesized and subjected to initial pharmacological evaluation in research conducted by the pharmaceutical company Roche.
1997:Clinical trials of it commenced. During these trials, experimenters set up that it displayed similar efficacity to intravenous administration of 5- fluorouracil( 5- FU), but with advanced tolerability and a more accessible route of administration.1998: The U.S. Food and Drug Administration (FDA) approved the marketing of it.
Further exploration and advancements Over time, exploration on it has continued with the end of optimizing lozenge, treatment rules, and combination remedy strategies to enhance effectiveness and reduce side goods.
In summary, with further exploration and clinical practice, we can anticipate ongoing advancements and a deeper understanding of it and its operations.
Basic Information
Product name | Capecitabine |
Chemical name | 5'-deoxy-5-fluoro-N-[(pentyloxy)carbonyl]-cytidine |
CAS | 154361-50-9 |
MF | C15H22FN3O6 |
MW | 359.35 |
EINECS | 604-948-1 |
MDL No. | MFCD00930626 |
Purity | 99% |
Stability | Stable |
Application | Medicine grade & Research grade. |
Packing | As per your request |
Storage | Room temp. |
Structural formula |
|
Quality standard
Test Items | Specifications | Result |
Appearance | White to off-white crystalline powder. | Off-white crystalline powder |
Solubility | Free soluble in methanol; soluble in Acetonitrile and in alcohol. Sparingly soluble in water. | Conforms |
Identification | Infrated Absorption | Conforms |
Retention time of the major peak in the chromatogram of assay corresponds to that in the chromatogram of the reference standard. | Conforms | |
Water Determination | ≤0.3% | 0.02% |
Optical Rotation | +96.0° ~ +100.0° | +97.5° |
Residue on Ignition | ≤0.1% | 0.01% |
Heavy metals | ≤20ppm | Conforms |
Related substances | Capecitabine related compound A≤0.3% | ND |
Capecitabine related compound B≤0.3% | 0.03% | |
2,3-Di-O-acetyl-5′-deoxy-5-fluorocytidine≤0.10% | 0.02% | |
5-Deoxy-5-fluoro-N4-(2-methyl-1-butyloxycarbonyl)cytidine + 5-Deoxy-5-fluoro-N4-(3-methyl-1-butyloxycarbonyl)cytidine ≤0.5% | ND | |
[1-[5-Deoxy-3-O-(5-deoxy-β-D- ribofuranosyl )-β-D- ribofuranosyl ]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]- carbamic acid pentyl ester≤0.3% | ND | |
[1-[5-Deoxy-2-O-(5-deoxy-β-D- ribofuranosyl )-β-D- ribofuranosyl ]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]-carbamic acid pentyl ester≤0.2% | ND | |
Capecitabine related compound C≤0.3% | ND | |
[1-[5-Deoxy-2-O-(5-deoxy-β-D- ribofuranosyl )-α-D- ribofuranosyl ]-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]-carbamic acid pentyl ester≤0.3% | ND | |
2,3-Di-O-acetyl-5-deoxy-5-fluoro-N4-(pentyloxycarbonyl) cytidine≤0.1% | ND | |
Individual unspecified impurity≤0.1% | 0.03% | |
Total impurities≤1.5% | 0.10% | |
Assay | 98.0%~102.0% on the anhydrous and solvent-free basis | 99.9% |
Conclusion: All the results conform to the requirement of USP | ||
Packaging and storage: Preserve in tight containers. Store at controlled room temperature. |
Storage
The storage conditions for Capecitabine API are as follows:
Temperature: Store it at room temperature, typically recommended within the range of 15°C to 30°C (59°F to 86°F).
Packaging: Ensure it is stored in a dry and well-sealed container. Original packaging is the best choice as they are specifically designed to protect the stability of the medication.
Light protection: It is photosensitive and exposure to light can cause its degradation. Therefore, during storage, it should be kept in light-protected containers as much as possible to minimize the impact of light exposure.
Humidity: It is sensitive to humidity and can readily absorb moisture and undergo hydrolysis reactions. To avoid this, it should be stored in a dry environment and ensure the container is well-sealed.
Storage location: Keep it in a place away from humidity, heat sources, and harmful chemicals.
Please note that these storage recommendations are for general reference. Specific storage conditions may vary depending on the brand, manufacturer, or specific requirements of the medication.
Packing & Shipping
Customization:Customized logo;Customized packaging;Graphic customization
Shipping:
Item | Quantity | ETA time | Shipping Method |
By Courier | ≤50kg | 7-15days | Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air | 50kg~200kg | 3-5days | Fast and cheap |
By Sea | Large quantity | 20-35days | Cheapest way |
Payment Term
Why Choose Xi'an Yihui?
Customer feedback
Xi'an Yihui certificates
Xi'an Yihui Factory & Warehouse
Our Advantage
Rich experience: we have 13 Years of professional experience;
Customers all over the world: sell to more than 100 countries;
Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.
Price advance: low MOQ with competitive price;
Quality certification: ISO; Halal; Kosher certified
After-sales service: Professional team 7*24 hours customer service.
In conclusion
In summary, as a Capecitabine powder factory, we will provide customers with high-quality Capecitabine API and professional services.
if you need it, pls feel free to contact us any time. we will reply you asap.
Our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937
Hot Tags: Capecitabine API, 154361-50-9, Capecitabine,Suppliers, Manufacturers, Factory, Bulk, Price, Wholesale, In Stock, Free Sample, Pure, Natural
Send Message
If you have any enquiry about quotation or cooperation, please feel free to email us at E-mailor use the following enquiry form. Our sales representative will contact you within 24 hours.Thank you for your interest in our products.