Cisatracurium Besylate Powder

CAS: 96946-42-8
Appearance: white powder
Standard: usp
Application: Muscle Relaxants
Brand: YIHUI
Packing: 100g;1kg
Supply Ability: 200kg per month
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse,1-3 days
Can't sell to individuals
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Product Introduction

What is Cisatracurium Besylate Powder?

Cisatracurium Besylate powder,  a neuromuscular impeding specialist, assumes a vital part in clinical settings, especially during surgeries that require muscle unwinding. This powder is fastidiously created by Yihui, a famous drug organization known for its obligation to greatness and adherence to severe quality norms.

During certain surgical procedures or when a patient requires mechanical ventilation, it may be necessary to temporarily paralyze their muscles to facilitate intubation, improve surgical access, or optimize mechanical ventilation settings. Cisatracurium besylate is administered intravenously to achieve this muscle relaxation.


Basic Information

Product Name: Cisatracurium besylate

CAS: 96946-42-8

MF:C53H72N2O12.2C6H5O3S

MW:1243.49

EINECS:620-579-9

MDL No.:MFCD00871018

Purity: 99%

Package: 1KG ;5kg

Used: Pharma grade &Lab research

Stability: Stable

Structural formula:

96946-42-8.webp

Specifications and Parameters:

TEST

STANDARD

RESULT

Characteristics

Appearance: White to off-while powder.

Conforms

Solubility

Freely soluble in chloroform and ethanol,   soluble in acetone

sparingly soluble in water.

Conforms

Identification

IR

Conforms

The retention time of the major peak of  the Sample solution corresponds 

to that of the Standard solution, as obtained   in the Assay.

Conforms

Methyl benzenesulfonate

NMT10ppm

Undetected

Specific rotation

-54°~-60°

-54.2°

Acidity

pH 3.5-5.0

4.5

Related substances

(1) Cis-Quaternary acid: NMT 0.2%

Undetected

(2)(R)-N-Methyllaudanosine: NMT 0.2%

Undetected

(3)(R)-Laudanosine: NMT 0.6%

0.20%

(4) Cis-Qualernary methyl ester: NMT 04%

0.18%

(5) Cis-Quaternary alcohol: NMT 0.5%

0.03%

(6) R-trans-R-rans-Atracurium:NMT0.2%

Undetected

(7) R-cis-R-trans-Atracurium:NMT 0.8%

0.16%

(8) Trans-Monoquaternary compound: NMT   0.5%

Undetected

(9) Trans-Monoacrylate: NMT 0.5%

Undetected

(10)Cis-Monoquaternarycompound:NMT 0.7%

Undetected

(11)Cis-cis-Triester analog: NMT 0.4%

Undetected

(12)Cis-Monoacrylate: NMT 1.0%

0.45%

(13)Any individual unspecifiedimpurity:   NMT 0.1%

Undetected

(14)Total impurities: : NMT 3.0%

1.0%

Water

NMT 5.0%

0.7%

Residue on ignition

NMT 0.1%

0.06%

Residual solvents

(1) Acetonitrile:NMT410ppm

Undetected

(2) Dichloromethane: NMT 600ppm

Undetected

(3) Ethyl ether: NMT5000ppm

603 ppm

(4)Toluene: NNT 890ppm

117 ppm

Assay

97.0%~102.0% on the anhydrous and   solvent-free basis)

99.8%

Result: In accordance withUSP39 and   client's special requirement

Packaging and storage: Preserve in tight,   light-resistant containers. Store cold, desiccated.

Chemical Composition:

IngredientPercentage Composition
Cisatracurium Besylate99% or higher
Excipients≤ 1%

Role and Function 

96946-42-8 goes about as a neuromuscular obstructing specialist, really instigating muscle unwinding during medical procedures. Its system includes serious threat with acetylcholine at the neuromuscular intersection, prompting controlled loss of motion. This works with intubation, mechanical ventilation, and surgeries requiring fixed status, guaranteeing ideal circumstances for clinical mediations.

The product's beginning of activity is quick, and its product of impact is painstakingly adjusted to satisfy the needs of different careful situations. The product gives a dependable and reversible neuromuscular bar, considering exact command over muscle capability all through operations.

Synthesis Process

Yihui utilizes a cutting edge union cycle to fabricate Cisatracurium Besylate Powder. The creation starts with the determination of great unrefined components. A progression of painstakingly controlled substance responses are then completed, prompting the development of it with extraordinary virtue. The union cycle is firmly checked to guarantee consistency and consistence with worldwide quality guidelines, mirroring Yihui's devotion to delivering drugs of the greatest type.

Quality Standards

Yihui is focused on keeping up with rigid quality principles all through the development of the product. We have ISO, Kosher, Halal, and GMP certifications for our manufacturing facilities, which adhere to international standards. These accreditations verify the unrivaled quality and immaculateness of our products, guaranteeing that medical services experts can depend on it for its security and viability in clinical applications.Here are some Quality Standards:

  • Appearance: White to grayish powder

  • ID: Ought to conform to the reference standard

  • Explicit pivot: Between - 69.0° and - 74.0°

  • Misfortune on drying: Not over 2.0%

  • Buildup on start: a maximum of 0.2 percent heavy metals: Not more than 20 ppm

  • Related substances: a) Pureness A: Not over 0.5% b) Some other debasement: Not over 0.2% c)

  • All out pollutions: Not over 1.0%

  • Measure (on dried premise): 98.5% to 101.5%

Application Fields in Various Industries

Cisatracurium Besylate finds diverse applications in the medical field, primarily in anesthesia and surgical settings. Its ability to induce controlled muscle relaxation makes it an indispensable component during procedures such as intubation and abdominal surgeries. Yihui's commitment to quality extends its application into pharmaceutical research and development, where precise neuromuscular modulation is essential for studying various physiological and pharmacological aspects.

Contact Us

As a leading manufacturer and supplier, Yihui takes pride in producing Cisatracurium Besylate Powder in strict accordance with international standards. Our certifications in ISO, Kosher, Halal, and GMP reflect our unwavering commitment to quality and safety. For inquiries or to purchase the product, please contact us at sales@yihuipharm.com. Trust Yihui for pharmaceutical excellence and reliability in every application.

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