Calcipotriol Monohydrate
CAS No.: 147657-22-5
MOQ: 1g
Assay: 99%
Brand: YIHUI
Packing: 1g;10g;100g
Supply Ability: 1000g per month
Delivery Time: Delivery within 3 days from warehouse after payment or order
Shelf Life: Two years
Payment: T/T, LC or DA
Standard: EP
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Product Introduction
What is Calcipotriol monohydrate?
Calcipotriol monohydrate also known as calcipotriene, it's a synthetic outgrowth of calcitriol, which is a form of vitamin D. It's a white or out-white crystalline solid with a molecular formula of C27H40O3 · H2O and a molecular weight of roughly 484.64. Its CAS number is 147657-22-5. Calcipotriol monohydrate is a hormone- suchlike substance that binds to vitamin D receptors to control cell division and proliferation in skin cells. It's primarily used to treat mild to moderate psoriasis, a habitual skin condition that constantly manifests and is distinguished by red patches, scales, and scratching. It reduces signs and detainments in the development of abnormal skin cells.
In addition, it can be used to treat associated skin disorders such as psoriatic arthritis. In the treatment of psoriasis, calcipotriol has undergone significant research and has been found to be comparatively safe and efficient. For patient convenience, it is frequently offered in topical formulations such as creams, sprays, and gels. Its effectiveness is currently being improved, and potential negative effects are being reduced.
Basic Information
Product name: Calcipotriol monohydrate
Other name: calcipotriene
CAS:147657-22-5
MF:C27H42O4
MW:430.63
EINECS:689-035-6
MDL No.:MFCD10567086
Storage: Store in an airtight container, Protected from light at -20℃ or below.
Used: research and pharma grade
Stability: Stable
Structural formula:
Quality standard
TEST | SPECIFICATION | RESULT | ||
Appearance | White or almost White, crystalline powder. | White or almost White, crystalline powder. | ||
Solubility | Practically insoluble in water, freely soluble in ethanol(96%), slightly soluble in methylene chloride | Conforms | ||
Identification | Identification A IR | Corresponds to the reference spectrum | Conforms | |
Identification B HPLC | The retention time of the major peak of the Sample solution corresponds to that of the Standard solution | Conforms | ||
Related compounds |
A: TLC | Impurity A NMT0.25% | Not detected | |
Rf=0.4(Impurity G or impurity H and the sum) NMT0.25%
| Not detected | |||
Any other individual impuirity NMT0.1%
| Not detected | |||
B: HPLC | Impurity B NMT0.5% | 0.076% | ||
Impurity C NMT1.0% | 0.507% | |||
Impurity D NMT1.0% | 0.041% | |||
Any other individual impuirity NMT0.1% | 0.016% | |||
Total impurities NMT 2.5% | 0.680% | |||
Residual solvents | Tetrahydrofuran NMT720ppm | 107ppm | ||
Ethyl acetate NMT5000ppm | 1053ppm | |||
Petroleum ether NMT1000ppm | Not detected | |||
Methanol NMT3000ppm | Not detected | |||
Toluene NMT890ppm | Not detected | |||
Methyl formate NMT5000ppm | Not detected | |||
Ethanol NMT5000ppm | Not detected | |||
Acetone NMT500 0ppm | Not detected | |||
Water | 3.3%-5.0% | 3.6% | ||
Assay | 97.0%~ 102.0% | 100.13% | ||
Conclusion: Complies with EP. |
Function & Application
The main function of Calcipotriol Hydrate is to treat psoriasis and other related skin conditions. Here are its functions:
Inhibition of abnormal cell growth: it regulates the proliferation and isolation of skin cells by binding to intracellular vitamin D receptors, thereby inhibiting the inordinate growth of skin cells in psoriasis cases and reducing the conformation of red patches and scales
Promotion of skin repair:it promotes the normal growth and tone- form of healthy skin cells, abetting in the restoration of damaged skin to a healthier state.
Relieving skin inflammation and vexation brought on by psoriasis is possible with the medicine, giving cases comfort and respite.
Enhancement of psoriatic arthritis:In addition to treating skin symptoms, it can also be used to reduce common pain and swelling associated with psoriatic arthritis.
Calcipotriol monohydrate is mainly used in the following areas:
Treatment of mild to moderate psoriasis:it's extensively used in the treatment of mild to moderate psoriasis, which is a common habitual autoimmune skin complaint. It reduces symptoms similar as greenishness, scales, and itching while controlling the abnormal proliferation of skin cells.
Treatment of psoriatic arthritis:it can also be used to treat psoriatic arthritis, which is a type of arthritis associated with psoriasis. It aids in the relief of symptoms like stiffness, edema, and common discomfort.
In addition to these main applications, it might also have potential value in the treatment of other skin issues.
Storage
It is a stable emulsion. still, to ensure the quality and effectiveness of the drug, the following storehouse conditions should be followed
Storage temperature: Calcipotriol monohydrate should be stored at a temperature at-20 ℃ or below.
Light: The drug should be defended from exposure to strong light to avoid reducing its energy. thus, it should be stored in a dry and dark place.
Packaging: The medication should typically be sealed in its original packaging and stored in a dry environment to prevent moisture absorption or other impacts.
Packing & Shipping
Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.
Customization: Customized logo; Customized packaging; Graphic customization
Shipping:
Item | Quantity | ETA time | Shipping Method |
By Courier | ≤50kg | 7-15days | Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air | 50kg~200kg | 3-5days | Fast and cheap |
By Sea | Large quantity | 20-35days | Cheapest way |
Lead time: Within 3 workdays after receiving payment.
Payment Term
Why Choose Xi'an Yihui?
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Our Advantage
Rich experience: we have 13 Years of professional experience;
Customers all over the world: sell to more than 100 countries;
Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.
Price advance: low MOQ with competitive price;
Quality certification: ISO; Halal; Kosher certified
After-sales service: Professional team 7*24 hours customer service.
In conclusion
In summary, as a professional Calcipotriol monohydrate manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Calcipotriol, pls feel free to contact us any time. we will reply to you ASAP.
Our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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