Calcipotriol Monohydrate

Product name: Calcipotriol monohydrate
CAS No.: 147657-22-5
MOQ: 1g
Assay: 99%
Brand: YIHUI
Packing: 1g;10g;100g
Supply Ability: 1000g per month
Delivery Time: Delivery within 3 days from warehouse after payment or order
Shelf Life: Two years
Payment: T/T, LC or DA
Standard: EP
  • Fast Delievery
  • Quality Assurance
  • 24/7 Customer Service
Product Introduction

What is Calcipotriol monohydrate?

Calcipotriol monohydrate also known as calcipotriene, it's a synthetic outgrowth of calcitriol, which is a form of vitamin D. It's a white or out-white crystalline solid with a molecular formula of C27H40O3 · H2O and a molecular weight of roughly 484.64. Its CAS number is 147657-22-5. Calcipotriol monohydrate is a hormone- suchlike substance that binds to vitamin D receptors to control cell division and proliferation in skin cells. It's primarily used to treat mild to moderate psoriasis, a habitual skin condition that constantly manifests and is distinguished by red patches, scales, and scratching. It reduces signs and detainments in the development of abnormal skin cells.

 In addition, it can be used to treat associated skin disorders such as psoriatic arthritis. In the treatment of psoriasis, calcipotriol has undergone significant research and has been found to be comparatively safe and efficient. For patient convenience, it is frequently offered in topical formulations such as creams, sprays, and gels. Its effectiveness is currently being improved, and potential negative effects are being reduced.

Basic Information

Product name: Calcipotriol monohydrate

Other name: calcipotriene

CAS:147657-22-5

MF:C27H42O4

MW:430.63

EINECS:689-035-6

MDL No.:MFCD10567086

Storage: Store in an airtight container, Protected from light at -20℃ or below.

Used: research and pharma grade

Stability: Stable

Structural formula:

147657-22-5.webp

Quality standard

TEST

SPECIFICATION

RESULT

Appearance

White or almost White, crystalline powder.

White or almost White, crystalline powder.

Solubility

Practically insoluble in water, freely soluble in ethanol(96%), slightly soluble in methylene chloride

Conforms

Identification

Identification A IR

Corresponds to the reference spectrum

Conforms

Identification B  HPLC

The retention time of the major peak of the Sample solution corresponds to that of the Standard solution

Conforms

Related compounds


               

A:

TLC

Impurity A NMT0.25%

Not detected

Rf=0.4(Impurity G or impurity H and the sum) NMT0.25%


               

Not detected

Any other individual impuirity NMT0.1%


               

Not detected

B:

HPLC

Impurity B NMT0.5%

0.076%

Impurity C NMT1.0%

0.507%

Impurity D NMT1.0%

0.041%

Any other individual impuirity NMT0.1%

0.016%

Total impurities NMT 2.5%

0.680%

Residual solvents

Tetrahydrofuran NMT720ppm

107ppm

Ethyl acetate NMT5000ppm

1053ppm

Petroleum ether NMT1000ppm

Not detected

Methanol NMT3000ppm

Not detected

Toluene NMT890ppm

Not detected

Methyl formate NMT5000ppm

Not detected

Ethanol NMT5000ppm

Not detected

Acetone NMT500 0ppm

Not detected

Water

3.3%-5.0%

3.6%

Assay

97.0%~ 102.0%

100.13%

Conclusion: Complies with EP.

Function & Application

The main function of Calcipotriol Hydrate is to treat psoriasis and other related skin conditions. Here are its functions:

  • Inhibition of abnormal cell growth: it regulates the proliferation and isolation of skin cells by binding to intracellular vitamin D receptors, thereby inhibiting the inordinate growth of skin cells in psoriasis cases and reducing the conformation of red patches and scales


  • Promotion of skin repair:it promotes the normal growth and tone- form of healthy skin cells, abetting in the restoration of damaged skin to a healthier state.

  • Relieving skin inflammation and vexation brought on by psoriasis is possible with the medicine, giving cases comfort and respite.

  • Enhancement of psoriatic arthritis:In addition to treating skin symptoms, it can also be used to reduce common pain and swelling associated with psoriatic arthritis.

Calcipotriol monohydrate is mainly used in the following areas:

  • Treatment of mild to moderate psoriasis:it's extensively used in the treatment of mild to moderate psoriasis, which is a common habitual autoimmune skin complaint. It reduces symptoms similar as greenishness, scales, and itching while controlling the abnormal proliferation of skin cells.

  • Treatment of psoriatic arthritis:it can also be used to treat psoriatic arthritis, which is a type of arthritis associated with psoriasis. It aids in the relief of symptoms like stiffness, edema, and common discomfort.

In addition to these main applications, it might also have potential value in the treatment of other skin issues.

Storage

  • It is a stable emulsion. still, to ensure the quality and effectiveness of the drug, the following storehouse conditions should be followed

  • Storage temperature: Calcipotriol monohydrate should be stored at a temperature at-20 ℃ or below.

  • Light: The drug should be defended from exposure to strong light to avoid reducing its energy. thus, it should be stored in a dry and dark place.

  • Packaging: The medication should typically be sealed in its original packaging and stored in a dry environment to prevent moisture absorption or other impacts.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Item

Quantity

ETA time

Shipping Method

By Courier

≤50kg

7-15days

Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air

50kg~200kg

3-5days

Fast and cheap

By Sea

Large quantity

20-35days

Cheapest way

Lead time: Within 3 workdays after receiving payment.

Payment Term

 payment.webp

Why Choose Xi'an Yihui?

Customer feedback

 Customer Comments.webp

Xi'an Yihui certificates

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Xi'an Yihui Factory & Warehouse

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

In summary, as a professional Calcipotriol monohydrate manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Calcipotriol, pls feel free to contact us any time. we will reply to you ASAP.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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