L-Epinephrine
CAS No.: 51-43-4
MOQ: 100g
Assay: 99%
Packing: 500g/bag;1kg/bag
Supply Ability: 500kg per month
Used: medicine grade or used for research
Delivery Time:in stock
Shelf Life: Two years
Payment: T/T, LC or DA
Can’t sell to individuals
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Product Introduction
What is L-Epinephrine?
L-Epinephrine is an odorless, tasteless, liquid powder that's white or out-white in color. It has a low solubility in water and is undoable in organic detergents like ethanol and chloroform. It dissolves readily in results of hydrochloric acid or sodium hydroxide. In logged or alkaline waterless results, it exhibits mild alkaline responses but becomes unstable. Its answerable in water hydrochloride swab is used the maturity of the time. A0.1 waterless result has a pH range of2.5 to5.0. Both the material and its mariners can be oxidized, deteriorated, and turn pink to sanguine- rown when exposed to oxidizing agents, alkalis, light, and heat.
L(-)- Epinephrine, frequently known as L- Adrenaline or Adrenaline, can be produced instinctively or naturally from the adrenal medulla of creatures( cattle, lamb). L-Adrenaline has the appearance of a white or out-white crystalline powder and acts as an activator on both and receptors. Epinephrine is buried by chromaffin cells in the adrenal medulla. Its main function is to regulate the sympathetic nervous system. Increased epinephrine stashing causes advanced blood pressure, a briskly twinkle, and more cardiacoutput.It accelerates fat metabolism, which raises metabolism, and promotes glycogenolysis in the liver, which elevates blood glucose situations. The bronchial smooth muscles are relaxed, among its other benefits. Stress, anxiety, fear, cold, and significant blood loss each markedly boost the sympathetic nervous system's exertion. As epinephrine stashing from the adrenal medulla increases, so do epinephrine situations within the body. When epinephrine interacts with adrenergic receptors, a multitude of physiological and metabolic changes do( and). When the sympathetic nervous system is actuated, the adrenal medulla releases two hormones epinephrine, which makes up 80% of the hormones, and norepinephrine, which makes up 20%.
Basic Information
Product name: L(-)-Epinephrine
CAS No.: 51-43-4
MF: C9H13NO3
MW:183.2
EINECS:200-098-7
Storage Temperature: 2-8°C
Stability: Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. Light sensitive.
Structural formula:
Quality standard
Items | Requirements | Results |
Description | White or almost white crystalline powder | Complies |
Identification | Positive | Positive |
Specific Rotation | - 50.0~- 53.5° | -51.0° |
Loss on drying | ≤2.0% | 0.41% |
Limit of norepinephrie | ≤2.0% | N.D |
Limit of adrenalone | A310nm0.2 | 0.05 |
Residue on ignition | ≤0.1% | 0.04% |
Assay (Dried) | 97.0-100.5% | 99.5% |
Conclusion Meets the Requirements |
Function & Application
L-Epinephrine can be used for a variety of purposes. Several typical uses and operations are listed below:
Cardiac support may be administered as an exigency treatment for heart failure or cardiac arrest. It activates beta receptors to increase heart rate and cardiac contractility, enhancing cardiovascular function.
Asthma treatment it's an exigency asthma remedy that can be employed in severe asthma attacks. Adrenaline powder can ease gasping, ease breathing issues, and relax bronchial smooth muscles.
Antipathetic responses Anaphylactic shock and other severe antipathetic responses can be treated with L(-)- epinephrine in an exigency. Rapid blood vessel condensation, dropped vascular leakage, mislike symptom relief, and preservation of pivotal organ function are all benefits.
Original hemostasis it's constantly given during operations or after trauma for original hemostasis. Hemostasis is backed by blood vessel condensation, which also lessens bleeding and prolongs vasoconstriction.
Original anesthesia To extend the anaesthetic effect and lessen medicine immersion and toxin, it's constantly used with original anesthetics.
Ophthalmic operations it has ophthalmic operations, including the treatment of glaucoma. It decreases waterless humor products, raises waterless humor exodus, and lowers intraocular pressure.
Substance interactions
The pressor goods of this drug can be combated by nascence- adrenergic receptor blockers and other vasodilators.
It can affect in arrhythmias, especially ventricular fibrillation, when combined with general anesthetics.
It can affect in arrhythmias when used with digitalis and tricyclic antidepressants.
It can affect in severe hypertension and towel ischemia when used in confluence with ergot medications like ergotamine.
It can result in hypertension and tachycardia when used with reserpine and guanethidine.
Beta-receptor actions of the two medications can cancel each other out when taken together, resulting in abnormally elevated blood pressure, bradycardia, and bronchospasm.
Combining additional sympathomimetic drugs may intensify their cardiovascular effects and raise their risk of side effects.
The pressor effects of this medication are offset when used with nitrate esters, and nitrate esters' anti-anginal effects are lessened.
It can strengthen the pressor effects of this medication when combined with monoamine oxidase inhibitors.
It can produce severe hypotension when used with chlorpromazine.
It can lessen insulin's and oral hypoglycemic agent's side effects when used along with anti-diabetic medications.
Stability & storage
As a rather unstable substance, Epinephrine powder is easily broken down by light, air, acids, and bases. The following storage circumstances are advised for stability:
Temperature: It should be kept chilled, typically between 2 and 8 degrees Celsius (36 and 46 degrees Fahrenheit). To avoid deterioration and loss of efficacy, stay away from hot and cold environments.
Light: Avoid being in the sun's direct or harsh light. To reduce exposure to light, It should be stored in opaque containers.
Packaging: To preserve it and prevent it from absorbing oxygen and moisture, use containers that are well-sealed.
pH Value: Avoid exposing it to acidic or alkaline conditions to preserve its stability. A neutral pH should always be maintained.
Packing & Shipping
Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.
Customization:Customized logo;Customized packaging;Graphic customization
Shipping:
Item | Quantity | ETA time | Shipping Method |
By Courier | ≤50kg | 7-15days | Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air | 50kg~200kg | 3-5days | Fast and cheap |
By Sea | Large quantity | 20-35days | Cheapest way |
Payment Term
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Rich experience: we have 13 Years of professional experience;
Customers all over the word: sell to more than 100 countries;
Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.
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In conclusion
In summary, as a professional L-Epinephrine manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need L-Adrenaline, pls feel free to contact us any time. we will reply you asap.
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