We supply Febantel API

We offer Febantel - an anthelmintic agent used to treat intestinal sponger infections in creatures. it works by dismembering the energy metabolism of the spongers, eventually leading to their death. It's primarily used to treat hookworms, roundworms, and tapeworms in tykes and pussycats. it is a safe and effective drug with no given adverse goods when used as directed. We give high- quality Febantel and guarantee timely delivery. Whether you are a pharmaceutical manufacturer or a veterinarian, we can meet your Febantel needs and offer competitive pricing to insure your satisfaction.

What is Febantel?

It is a chemical substance, also known as phenylthioguanidine, and its English name is methyl N-( N-( 2-(( 2- methoxyacetyl) amino)-4-phenylsulfanyl-phenyl)- N'- methoxycarbonyl- carbamimidoyl) carbamate. The molecular formula is C20H22N4O6S, and the molecular weight is446.477.

The broad- diapason anthelmintic Febantel, also known as phenylthioguanidine, is substantially used to treat and control gastrointestinal roundworms, lungworms, tapeworms,etc. in cattle, lamb, gormandizers, nags and other creatures. It has the characteristics of high effectiveness, low toxin, short hearthstone time in the body, and a wide range of safety. As a prodrug, it's metabolized( cyclized) in the body to the antiparasitic medicine fenbendazole, or further metabolized( sulfur snippet oxidation) to oxfendazole. It was first successfully developed by Bayer Pharmaceuticals in Germany, and its synthetic route is infrequently reported in China. The retailed product Drontalplus is a emulsion broad- diapason anthelmintic containing three active constituents febantel, praziquantel and pyrantel pamoate. It's an anthelmintic for tykes produced by Bayer HealthCare AG. It has been registered and used in further than 30 countries and can be used to exclude a variety of gastrointestinal worms in tykes .

Basic Information

Product Name: Febantel

CAS: 58306-30-2

MF:C20H22N4O6S

MW:446.48

EINECS:261-205-0

MDL No.:MFCD01738527

Melting point:129-130°C

Boiling point:215°C (rough estimate)

Density 1.2962 (rough estimate)

Structural formula:

Application: Anti-Parasitic

Origin: China

Delivery Time: in stock

Technical Specification

Package: 25kg; or according to your demands

Storage conditions:2-8℃, protected from light and moisture, sealed and dry

Transportation conditions: 2-8 ℃ transportation

Shelf Life:24 months

Application

Febantel  is primarily used in veterinary drug, specifically for the treatment of parasitic infections in creatures. Then’s an overview of its Application and Application

Anthelmintic Agent: it is extensively used as an anthelmintic agent in veterinary drug. It's effective against colorful intestinal spongers, including nematodes( roundworms) and cestodes( tapeworms), generally set up in tykes and pussycats.

Diapason of exertion: it acts by dismembering the metabolism of parasitic worms, leading to their palsy and posterior expatriation from the gastrointestinal tract of creatures. It's effective against spongers similar as Toxocara, Toxascaris, Ancylostoma, Trichuris, and Taenia species.

phrasings: it is formulated into colorful lozenge forms similar as tablets, dormancies, or maquillages for oral administration to creatures. These phrasings are designed to insure proper lozenge and effective treatment against specific spongers.

Combination Products: it is frequently combined with other anthelmintic agents similar as praziquantel or pyrantel pamoate to broaden its diapason of exertion. These combinations are particularly useful for treating mixed parasitic infections in faves .

Lozenge and Administration: The lozenge varies depending on the type of sponger being treated and the beast's weight. Veterinary professionals determine the applicable lozenge authority grounded on the specific requirements of the beast.

Safety and Side goods : it is generally well- permitted by creatures when used according to veterinary guidelines. still, like all specifics, it can potentially beget side goods similar as gastrointestinal worried in some cases.

Regulatory Considerations Regulatory agencies, similar as the FDA( Food and Drug Administration) in the United States and the EMA( European Medicines Agency), oversee the blessing and regulation of veterinary medicines like it to insure their safety and efficacity.

Pharmacological action

it is a broad- diapasonanti-tapeworm medicine. After contact with the worm, it causes tonic compression of the worm's muscles and produces discontinuous palsy. it has a rapid-fire and egregious dangerous effect on the cortex of the worm, causing lump of the syncytial epidermis, vacuoles, bullae, pooching

from the body face, and ultimately corrosion and ulceration of the epidermis. The secretory body nearly disappears, and the indirect muscle and longitudinal muscle snappily dissolve one after another. After the cortex is damaged, the immersion and excretion function of the worm is affected. More importantly, its face antigens are exposed, making it vulnerable to the host's vulnerable attack. A large number of eosinophils attach to the skin lesions and foray , causing the worm to die. In addition, it can also beget secondary changes, depolarizing the worm's face membrane, significantly reducing the exertion of cortical alkaline phosphatase, inhibiting glucose uptake, and depleting endogenous glycogen; it can also inhibit the conflation of nucleic acid and protein in the worm.

Content determination

High performance liquid chromatography determination

Chromatographic conditions and system felicity test, using octadecylsilane clicked silica gel as padding,0.05 spook/ L potassium dihydrogen phosphate result- acetonitrile( 5743) as mobile phase, discovery wavelength is 280nm. The number of theoretical plates is calculated grounded on thenon-bantel peak, which shouldn't be lower than 2500, and the separation degree between thenon-bantel peak and the imidazole urethane, methoxymethylimidazole and methoxycarbonylguanidine peaks should meet the conditions.

Determination system

Take about 50 mg of this product, directly weigh it, put it in a 50 ml volumetric beaker, add acetonitrile to dissolve and adulterate to the scale, shake well, directly measure 20μl, fit it into the liquid chromatograph, and record the chromatogram; take anothernon-bantel reference substance and determine it in the same way. Calculate by peak area according to the external standard system to get it.

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In summary, as a professional Febantel manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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