We supply Oclacitinib Maleate

Our company supplies high- quality Oclacitinib Maleate, a potent asset of Janus kinase( JAK) that's used to treat atopic dermatitis and antipathetic skin conditions in tykes . It has been proven effective in reducing skin inflammation, itching, and scratching in canine cases. Our product is manufactured under strict quality control guidelines to insure chastity and thickness in every batch. We're committed to furnishing dependable and effective service to meet the requirements of our guests. communicate us to learn further about our Oclacitinib and how it can profit your veterinary practice.

What's Oclacitinib Maleate( PF- 03394197)?

Oclacitinib Maleate, also known by its development law PF- 03394197, is a picky Janus kinase( JAK) asset used for the treatment of atopic dermatitis( announcement) in tykes . It's a small patch and works by blocking JAK 1 and JAK 3-dependent cytokines, which are crucial factors in the development of announcement.

Atopic dermatitis is a common seditious skin complaint in tykes characterized by pruritus( itching), erythema( reddening of the skin), and lichenification( thickening of the skin). It can have a significant negative impact on the quality of life of both tykes and their possessors. Oclacitinib offers a targeted treatment option for tykes with announcement and has demonstrated efficacity in reducing pruritus and clinical signs in multiple clinical trials.

it is available as a tablet for oral administration and can be specified by a veterinarian. It generally requires diurnal dosing for the first 14 days, followed by every other day dosing for conservation treatment. It's important to consult with a veterinarian to determine the applicable treatment authority for each individual canine.

Overall, it provides a promising treatment option for tykes suffering from atopic dermatitis. Its targeted medium of action and demonstrated efficacity make it a precious addition to the treatment armamentarium for this common and grueling complaint in veterinary drug.

Basic Information

Product Name: Oclacitinib Maleate(PF-03394197)

CAS: 1208319-27-0

MF:C19H27N5O6S

MW:453.51

EINECS:200-001-8

MDL No.:MFCD30533388

Structural formula:

Application: Antipruritic and anti-inflammatory

Origin: China

Delivery Time: in stock

Technical Specification

Package 10g;100g; 1kg, or according to your demands

Storage conditions: Preserve in tightly closed container between 2～8℃

Transportation conditions: Transportation at room temperature

Shelf Life: 24 months

Application

Oclacitinib maleate is a drug primarily used in veterinary drug, particularly for tykes . It's a Janus kinase( JAK) asset that helps manage and treat certain seditious and antipathetic conditions. Then are its main applications:

Treatment of Antipathetic Dermatitis: it is generally used to treat antipathetic dermatitis in tykes . This condition can be caused by colorful allergens, including food, environmental factors, or flea mouthfuls. The drug helps reduce itching and inflammation associated with these antipathetic responses.

Application of Atopic Dermatitis: Atopic dermatitis is a habitual skin condition in tykes characterized by severe itching, greenishness, and skin lesions. it effectively reduces the symptoms by inhibiting the JAK pathways involved in the seditious response.

Control of Pruritus: Pruritus( itchiness) in tykes , anyhow of the underpinning cause, can significantly affect their quality of life. it provides rapid-fire relief from itching, making it a precious option for managing acute flare- ups and habitual itching.

Adjunct remedy for Other Conditions:  In some cases, it may be used as part of a broader treatment plan for other conditions that involve inflammation and itching. It can be combined with other specifics or treatments to ameliorate overall efficacity.

Flea Allergy Dermatitis: For tykes suffering from flea mislike dermatitis, it can help palliate the violent itching and skin vexation caused by flea mouthfuls.

it is retailed under the brand name Apoquel and is available by tradition from veterinarians. It's generally administered orally in tablet form. The medicine works by widely inhibiting specific JAK enzymes, which play a pivotal part in the signaling pathways that lead to inflammation and itching.

Its benefits include its rapid-fire onset of action, frequently furnishing relief within hours, and its targeted medium, which minimizes implicit side goods compared to broader immunosuppressive medicines. still, it's important for veterinarians to cover tykes on this drug for any adverse goods or complications, and it should be used according to the specified lozenge and guidelines.

Biological activity

it is a prominent asset of the Janus kinase( JAK) family used to treat skin disinclinations and inflammation in tykes . It's a potent and picky asset of JAK1 and JAK3, which are crucial enzymes involved in the signal transduction process in vulnerable cells. By blocking the JAK- STAT pathway, Oclacitinib can inhibitpro-inflammatory cytokines( similar as IL- 2, IL- 4, IL- 6, IL- 31, and IL- 17) and promoteanti-inflammatory cytokines( similar as IL- 10) product. This can help to reduce itchiness, inflammation, and other symptoms associated with skin disinclinations in tykes .

it has been clinically proven to be largely effective in treating antipathetic skin conditions in tykes , including atopic dermatitis, flea mislike, and food mislike. It's the only medicine approved by the FDA for treating canine atopic dermatitis, a habitual and enervating antipathetic skin condition that affects up to 10 of tykes . it has been shown to give rapid-fire relief of pruritus( itching), ameliorate quality of life, and have an excellent safety profile with no given serious side goods. It's available in tablet form, making it easy to administer to tykes .

In summary, it is a important medicine that can control the symptoms of antipathetic skin conditions in tykes . It works by blocking the JAK- STAT pathway, reducing inflammation and pruritus. It has been clinically proven to give rapid-fire and long- continuing relief of itching and ameliorate the quality of life of tykes suffering from skin disinclinations. With its high efficacity and excellent safety profile, it is a trusted tool used by veterinarians to help palliate the suffering of numerous tykes with antipathetic skin conditions.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Lead time: Within 3 workdays after receiving payment.

Payment Term

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In summary, Xi'an Yihui company as a professional Oclacitinib maleate produced manufacturer, has strong technical strength and advanced production equipment, and is committed to providing customers with high-quality, efficient and reliable drug raw materials.

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Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937