Moxidectin powder
Appearance: White or pale yellow amorphous powder
Standard: USP
Supply Ability: 500kg per month
Shelf Life: Two years
Payment: T/T, LC or DA
Delivery Time: Ready Stock
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Can't sell to individuals
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Product Introduction
We supply Moxidectin API
We're a manufacturer of Moxidectin API, a important parasitic medicine extensively used in veterinary drug. Our product is of the loftiest chastity and quality, icing maximum effectiveness in treating a range of spongers including worms, diminutives, and lice. it has a long- continuing effect and a wide safety periphery, making it a popular choice among veterinarians and beast possessors likewise. Whether you need Moxidectin powder for cattle, nags, tykes, or other creatures, we can give you with the right result. Trust us for dependable, proven, and affordable Moxidectin.
What is Moxidectin API powder?
Moxidectin is a potent and broad- diapason antiparasitic medicine that's generally used in veterinary drug. This is due to its capability to effectively control a wide range of spongers in creatures, including diminutives, ticks, lice, and nematodes. it belongs to the macrocyclic lactone family of medicines and workshop by snooping with the nervous system of spongers, leading to palsy and death.
It is largely effective against a number of important veterinary spongers, including heartworm, intestinal worms, and mange diminutives. It's also effective against external spongers similar as ticks and lice, making it a precious tool in the operation of beast and companion creatures. This broad- diapason exertion makes it a favored remedial option for numerous veterinarians.
One of the crucial advantages is its long duration of action. This means that a single cure can give sustained protection against parasitic infections for over to several weeks. This not only reduces the frequence of dosing needed but also improves compliance with treatment rules. In addition, it is generally well- permitted, with many reported side goods.
Basic Information
Product Name: Moxidectin
CAS:113507-06-5
MF:C37 H53 N O8
MW:639.82
EINECS:635-129-7
MDL No.:MFCD00866560
Structural formula:
Purity: 99%+
Origin: China
Application: Antiparasitic
Melting point: 132 ° C
Boiling point: 790.0 ± 70.0 ° C (Predicted)
Density: 1.23 ± 0.1 g/cm3 (Predicted)
Solubility: in ethanol≥ 128 mg/mL; in DMSO≥ 129.4 mg/mL; Under mild heating and ultrasound, water ≥ 3.27 mg/mL
Technical Specification:
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Test Items |
Specification |
Result |
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Appearance |
White or pale yellow amorphous powder |
White amorphous powder |
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|
Identification |
IR spectrum of sample corresponds to that of reference substance |
Comply |
||
|
|
The retention time of the major peak of the Sample solution corresponds to that of the Standard solution,as obtained in the Assay |
Comply |
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Water |
≤1.3% |
0.6% |
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Residue on ignition |
≤0.2% |
0.04% |
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Heavy metals |
≤20ppm |
<20ppm |
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Assay (anhydrous basis) |
92.0%~102.0% |
98.2% |
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Organic impurities |
Early-eluting impurities |
Moxidectin butenyl analog (A) ≤1.5% |
0.1% |
|
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5'-Demethyl moxidectin (B) ≤0.5% |
0.2% |
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Moxidectin pentenyl analog(C) ≤1.5% |
0.4% |
|||
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Moxidectin 17a-epimer(D) ≤2.5% |
0.2% |
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Sum of moxidectin 19-S-17a-ene and moxidectin ethyl isomers(E+F)≤1.7% |
0.3% |
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Milbemycin B analog (moxidectin open ring)(G) ≤1.5% |
Not detected |
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Any other individual impurity eluting before milbemycin B analog (moxidectin open ring) ≤0.5% |
|
0.2% |
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Late-eluting impurities |
Moxidectin deoxydienea. and 4'-Methylthiomethoxymoxidectin(H+I)≤1.0% |
Not detected |
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20b-Methylthiomoxidectin(J) ≤0.5% |
Not detected |
|||
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20-Nitrobenzoylmoxidectin(k) ≤0.5% |
Not detected |
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Any other individual impurity eluting after the milbemycin B analog (moxidectin open ring) ≤0.5% |
Not detected |
|||
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Total organic impurities |
≤7.0% |
1.7% |
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|
Solvent residue |
Methanol ≤3000ppm |
Not detected |
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Methylene chloride ≤300ppm |
Not detected |
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Isopropyl acetate ≤5000ppm |
Not detected |
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N-heptane ≤5000ppm |
72ppm |
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BHT |
0.3%~0.6% |
0.49% |
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Conclusion |
The product complies with the specification (USP) |
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Storage |
Preserve in well-closed, light-resistant containers, and store in room temperature |
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Package: 100g; 1kg;25kg
Storage conditions: Keep in dark place, Inert atmosphere,2-8°C
Safety Information
Dangerous goods label: T, N
Hazard category code: 25-50
Safety instructions: 45-61-24/25
Dangerous goods transportation number: 2588
WGK Germany: 3
RTECS number: PY5438800
Hazard level: 6.1 (b)
Packaging category: III
Customs code: 29322090
What is the Pharmacological action of Moxidectin API?
Moxidectin API is a broad-spectrum antiparasitic agent that belongs to the macrocyclic lactone class of compounds. It is derived from a strain of Streptomyces cinnamoneus and is structurally similar to other macrocyclic lactones such as ivermectin and doramectin.
it exerts its pharmacological action through the potent and selective activation of glutamate-gated chloride ion channels (GluCls) in the nervous system of parasites. This results in increased neuronal excitability, paralysis, and ultimately death of the parasite. it has a high affinity and long-acting effect on the GluCls of nematodes and arthropods, making it an effective treatment for a wide range of parasitic infestations in animals.
it is highly effective against a variety of parasites, including intestinal nematodes, lungworms, mites, and lice. It has been shown to provide rapid and long-lasting protection against heartworm disease in dogs and cats. It is also effective against gastrointestinal nematodes in cattle, sheep, and horses.
it has a low toxicity in mammals and is well tolerated by most animals, including pregnant and lactating females. It is readily absorbed and distributed throughout the body after administration, with a half-life of approximately 28 days in cattle and 42 days in sheep.
In conclusion, it is a potent and effective antiparasitic agent that offers fast and long-term protection against a wide range of parasites in animals. Its unique mode of action and low toxicity make it a valuable tool in the fight against parasitic infestations.
What is the application of Moxidectin API?
Moxidectin powder is a highly effective parasiticide used to treat and prevent a variety of parasitic infestations. This powerful drug has a broad spectrum of activity, making it effective against both internal and external parasites such as heartworms, roundworms, mites, and ticks.
it is commonly used in the veterinary industry to treat a wide range of animal species, including dogs, cats, horses, and cattle. It is typically administered orally or injected subcutaneously, depending on the specific application and animal species.
In addition to its use in animal health, it is also used in the treatment of certain human parasitic infections. For example, it has been used to treat river blindness, a debilitating disease caused by parasitic worms that affects millions of people worldwide.
it is a highly effective and safe drug, and it is widely used due to its efficacy, safety, and versatility. Its broad spectrum of activity makes it a valuable tool in the fight against parasitic infections in both animals and humans. With its many applications and proven track record of success, it is no wonder that it continues to be a popular choice for veterinarians, doctors, and researchers worldwide.
Animal use range
Moxidectin has been approved for use in the treatment of filariasis, according to two studies conducted in 2018 in people aged 11 and above in the United States who were river blind. It is necessary to conduct other long-term follow-up trials to evaluate the safety and efficacy of moxifloxacin in treating nematode infections in children and women with fertility. Moxibustin is expected to help achieve the goal of eliminating the disease. Dog: Prevent filariasis. Horses: Treatment for parasites including roundworms and gastro chemical book robots such as gastrointestinal and small intestine. Cattle: Treatment for parasites such as gastrointestinal worms, oysters, and lung worms, placental worms. Sheep: Treatment for nematodes, roundworms, and twisted blood spear nematodes. Nematodes can develop cross resistance between moxicycline and other similar parasitic agents, such as ivermectin, doxorubicin, and avermectin. Moxicycline is being evaluated as a treatment for scabies in humans, especially when they are resistant to other therapies.
Our Advantage
Rich experience: we have 13 Years of professional experience;
Customers all over the world: sell to more than 100 countries;
Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.
Price advance: low MOQ with competitive price;
Quality certification: ISO; Halal; Kosher certified
After-sales service: Professional team 7*24 hours customer service.
In conclusion
In summary, as a supplier of Moxidectin powder , Xi'an Yihui has rich production experience and technical knowledge, high-quality products, flexible production capacity, and quality customer service, which can provide better support and service to customers.
if you need Moxidectin API, pls feel free to contact us any time. we will reply you asap.
Our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937
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