Diclazuril powder
Appearance: off-white or yellowish powder
Standard: CP grade, 99%
Supply Ability: 5000kg per month
Shelf Life: Two years
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Can't sell to individuals
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Product Introduction
We supply Diclazuril powder
We're pleased to offer Diclazuril powder, a largely effective anthelmintic agent used in the forestallment and treatment of coccidiosis in flesh, gormandizers, and other beast. Our product is of the loftiest quality, manufactured to strict norms to insure chastity and effectiveness. it is easy to use and has been proven in clinical studies to be safe and effective in treating coccidiosis. Whether you're a small- scale planter or a large marketable operation, our Diclazuril is a dependable and effective result for controlling coccidiosis and maintaining the health of your creatures. communicate us for further information and to place your order moment!
What's Diclazuril?
Diclazuril is a potent and effective veterinary medicine used to control coccidiosis, a parasitic complaint that affects colorful creatures. Coccidiosis can beget severe illness, growth deceleration, and indeed death in creatures if left undressed. still, with it , forestallment and treatment of this complaint has come much easier.
it is a member of the benzeneacetonitrile class of composites and workshop by dismembering the life cycle of coccidia, thereby precluding them from reproducing and causing damage to the host beast. It's largely picky, only targeting coccidian spongers and sparing the salutary microorganisms in the beast's gut.
it is available in colorful forms, including oral dormancies, maquillages, and premixes for easy administration to different beast species. It has been proven to be effective in controlling coccidiosis in flesh, cattle, lamb, scapegoats, and other creatures, therefore helping to ameliorate their health and productivity.
One of its significant advantages is its safety profile. It's well permitted by creatures, with no serious side goods observed when administered according to recommended cure situations. still, as with any medicine, it's essential to follow the instructions and consult a veterinarian before using it.
In conclusion, it is a vital medicine in the veterinary drug world. It's effective, safe, and easy to administer, making it an ideal choice for precluding and treating coccidiosis in creatures. With it, growers and beast possessors can rest assured that their creatures will remain healthy and productive, free from the ruinous goods of coccidia.
Basic Information
Product Name: Diclazuril
CAS:101831-37-2
MF:C17H9Cl3N4O2
MW:407.64
EINECS:1806241-263-5
MDL No.:MFCD00867203
Structural formula:
Purity: 99%+
Origin: China
Application: Anti coccidiotic
Delivery Time: 3-7days
Melting point: 290.5℃
Density: 1.56 ± 0.1 g/cm3 (Predicted)
Technical Specification:
Testing Items |
Specifications |
Results |
1. Appearance |
off-white or yellowish powder |
off-white powder |
2. Identification |
A. Light absorption |
Conform |
B. IR test |
Conform |
|
3.Melting Point |
290-297.0℃ |
Conform |
3.Relative substances |
(TLC) ≤2.5% |
<2.5% |
4. Loss on Drying |
≤0.5% |
0.45% |
6. Residuals on ignition |
≤0.1% |
<0.1% |
5. Heavy Metals |
≤20ppm |
<20ppm |
6. Assay (HPLC) |
≥96% |
96.1% |
Conclusion |
Comply wither CP |
Package: 1kg; 25kg
Storage conditions: keep tightly closed, store in a cool dry place.
Safety Information
Safety instructions: 24/25
WGK Germany: 2
RTECS number: CY1697600
Customs code: 29336990
What is the function?
Diclazuril powder is a highly effective drug used for the prevention and treatment of coccidiosis in animals. Coccidiosis is a common intestinal disease caused by protozoan parasites that affects a wide range of animals, including chickens, pigs, and cows. it works by inhibiting the growth and reproduction of these parasites, thereby reducing the severity of the disease and preventing its spread to other animals.
It is known for its remarkable efficacy in controlling coccidiosis, with a high success rate and low incidence of side effects. It acts by disrupting the life cycle of the coccidia, preventing them from multiplying and causing damage to the intestinal lining. As a result, animals treated with it experience reduced morbidity, better growth performance and higher feed conversion ratio.
One of the key benefits is its versatility. It can be used for both prophylactic and therapeutic purposes, as well as in combination with other drugs or as a single agent. It is particularly useful in intensive animal production systems, where coccidiosis can easily spread and cause significant economic losses.
it is easy to administer and has a good safety profile. It can be administered orally or via intramuscular injection, depending on the animal species and age. It is rapidly absorbed and distributed throughout the body, and then metabolized and excreted through the liver and kidneys. Although adverse reactions are rare and generally mild, precautions should be taken in animals with impaired liver function or hypersensitivity to the drug.
In summary, it is an invaluable tool for the control of coccidiosis in animals. Its unique mode of action, high efficacy and good safety profile make it a preferred choice for veterinarians and animal owners worldwide.
What is the application?
Diclazuril is a potent anticoccidial drug widely used in veterinary medicine to prevent and treat coccidiosis in poultry and other farm animals such as pigs, rabbits, and sheep. It belongs to the benzeneacetonitrile derivative class of drugs and has a high affinity for the cyst wall of coccidian parasites.
Coccidiosis is a highly infectious parasitic disease caused by the protozoan parasite Eimeria species. The disease is common in poultry and can lead to significant economic losses due to reduced productivity, mortality, and increased cost of treatment. it is an effective treatment for coccidiosis and is widely used in poultry and other farm animals.
The application is straightforward. It is either included in the feed or given as a standalone liquid medication to the animal at specific doses to prevent an outbreak of coccidiosis. Unlike other anticoccidial drugs, it has a wide therapeutic index and can be administered at higher levels without causing any adverse effects to the animal.
it works by preventing the development of Eimeria oocysts in the animal's gut. The drug inhibits the growth and replication of the parasite, leading to a reduction in the severity of the disease and faster recovery. The drug is also effective against multiple strains of Eimeria species, making it an ideal medication to prevent and treat coccidiosis in veterinary medicine.
In conclusion, it is a highly potent anticoccidial drug that has proven effective in preventing and treating coccidiosis in poultry and other farm animals. Its safety, efficacy, and wide therapeutic index make it an ideal drug for use in veterinary medicine, ensuring the health and productivity of animals while reducing economic losses associated with coccidiosis outbreaks.
Synthetic preparation
Using methanol as a solvent, 2,6-dichloride was synthesized using hydrogen gas under the catalysis of 5% platinum carbon- α- (4-Chlorophenyl) -4-nitrophenylacetonitrile (A) is hydrogenated and reduced to 4-amino-2,6-dichloro- α- (4-Chlorophenyl) phenylacetonitrile (B). (B) Through diazotization and coupling reactions, 2- [3,5-dichloro-4- [(4-chlorophenyl) cyanomethyl] phenyl] hydrazide] -2-cyanoacetylaminoformate ethyl ester (C) is generated. (C) is cyclized and hydrolyzed to form 2- [3,5-dichloro-4- [(4-chlorophenyl) cyanomethyl] phenyl] -2,3,4,5-tetrahydro-3,5-dicarbonyl-1,2,4-triazine-6-carboxylic acid (D). Using mercaptoacetic acid as a solvent, (D) undergoes decarboxylation reaction at 170 ℃ to generate diclazulide. The process of cyclization and hydrolysis is as follows: 7.8 parts of compound (C), 1.98 parts of anhydrous potassium acetate, and 120 parts of glacial acetic acid are stirred and refluxed for 3 hours. After adding an appropriate amount of glacial acetic acid and 30 parts of concentrated hydrochloric acid, continue stirring and refluxing for 10 hours; Then concentrate, cool, and filter, and the filter cake becomes compound (D).
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