We supply Pyrimethamine API

We're proud to offer Pyrimethamine powder, a largely effective drug used to treat and help malaria by killing the malaria spongers in the blood. Our product is of the loftiest quality and chastity, icing the stylish results for any treatment authority. It's suitable for both adult and pediatric cases, making it a protean choice for healthcare providers. Trust in our Pyrimethamine API to effectively combat malaria and ameliorate patient health.

What's Pyrimethamine?

Pyrimethamine is a broad- diapason veterinary medicine extensively used for antigen worms. In addition, it's also used in monoculture to enhance the complaint resistance of submarine fish. still, the side goods of pyrimidine are significant, and inordinate use can damage the reproductive system of beast and flesh, making it delicate to recover. it has an inhibitory effect on the primary infrared phase of certain nasty malaria and vivax malaria, and is a good preventative medicine. Although it has no significant effect on the gametophytes of malaria spongers, the entry of medicine- containing blood into mosquito bodies can affect the development of gametophytes in mosquitoes, therefore blocking transmission. The principle of action is to inhibit dihydrofolate reductase, affect the application of tetrahydrofolate, reduce nucleic acid conflation, and inhibit the reduplication of malaria spongers. At the same time, pyrimidine and chloroquine have a defensive effect on placental pathological changes after malaria infection by reducing oxidative stress and cell apoptosis situations. They can also effectively reduce the proportion of infected red blood cells in the blood, therefore achieving good malaria treatment goods. also, submarine products have an enrichment effect in the body, exceeding a certain range. After consumption by humans, it can beget hemolytic anemia and indeed have direct toxin to the central nervous system. This product is substantially used for the forestallment of malaria and can also be used for the treatment of toxoplasmosis. It has an inhibitory effect on the primary infrared phase of certain nasty malaria and vivax malaria, and is a good preventative medicine. Due to slow excretion and long- lasting goods, taking drug at formerly can maintain its preventative effect for further than a week. This product has no significant effect on the gametophytes of malaria spongers, but when mosquitoes gobble blood containing this medicine, it can affect the development of gametophytes in mosquitoes, therefore blocking transmission. Due to its effect on the infrared phase of malaria spongers, it's frequently used in combination with primaquine to help rush. This product is a white crystalline greasepaint; Odorless and tasteless. undoable in water, slightly answerable in ethanol, chloroform, acetone, and answerable in dilute mineral acids. The melting point is between 232 and 235 ℃.

Basic Information

Product Name: Pyrimethamine

CAS:58-14-0

MF:C12H13ClN4

MW:248.71

EINECS:200-364-2

MDL No.:MFCD00057350

Structural formula:

Purity: 99%+

Origin: China

Application: Antimalarial

Delivery Time: 3-7days

Melting point: 233-234℃

Boiling point: 393.35 ℃ (rough estimate)

Stability: Stable, but sensitive to light. Flammable. Incompatible with strong oxidizing agents.

Technical Specification

Package: 1kg; 25kg

Storage conditions: keep tightly closed, store in a cool dry place.

Safety Information

Dangerous goods label: Xn

Hazard category code: 22-36

Safety instructions: 26

Dangerous goods transportation number: 3249

WGK Germany: 3

RTECS number: UV8140000

Hazard level: 6.1 (b)

Packaging category: III

Customs code: 29335990

Toxic Substances Data: 58-14-0(Hazardous Substances Data)

Toxicity: LD50 oralin rat: 440mg/kg

What is the function？

Pyrimethamine powder is a pharmaceutical drug that belongs to the class of antiparasitic medications. It is mainly used for the prevention and treatment of malaria, a serious and potentially life-threatening disease caused by a parasitic protozoan transmitted by the Anopheles mosquito. it works by inhibiting the growth and replication of the parasite, thereby reducing its ability to cause harm to the host.

it is most commonly used in combination with other antimalarial drugs, such as sulfadoxine, to provide effective treatment for malaria infections. It is also used for the prevention of malaria in individuals traveling to endemic regions.

Aside from its antiparasitic properties, it has also been used as an adjunct therapy in the treatment of certain types of cancer, such as lymphoma and leukemia. It works by inhibiting the activity of dihydrofolate reductase, an enzyme that is essential for the synthesis of DNA and RNA. This inhibition prevents the cancer cells from dividing and growing, thereby reducing the overall tumor burden.

it is available in various forms, including tablets, capsules, and injectable solutions. It is usually taken orally once a week as a prophylactic measure for malaria prevention, and the dosage may vary depending on the individual's age, weight, and medical history. For the treatment of malaria, it is typically given in combination with other antimalarial drugs in a carefully monitored regimen.

Like all medications, it may cause side effects, such as nausea, vomiting, headache, and dizziness. It should not be taken by individuals who are allergic to the drug or who have certain medical conditions, such as liver or kidney disease. Pregnant women and nursing mothers should also exercise caution when taking it, as it may affect fetal development or be excreted into breast milk.

In conclusion, it is an essential antiparasitic drug that plays a critical role in the prevention and treatment of malaria. Its effectiveness and potential applications in other medical fields make it an important tool in modern medicine. However, it should always be used under the guidance of a qualified medical professional to ensure safety and efficacy.

What is the application？

Pyrimethamine is a medication that is primarily used to treat and prevent malaria. It is also used in the treatment of certain parasitic infections, such as toxoplasmosis. it works by disrupting the growth and reproduction of the parasites, thereby preventing the spread of the infection.

In addition to its use as an antimalarial drug, it is important in the treatment of toxoplasmosis, a parasitic infection that can cause serious health problems for people with weakened immune systems. In conjunction with other medications, it is used to prevent the spread of the infection and reduce the symptoms associated with toxoplasmosis.

it is available in several different forms, including tablets, injectable solutions, and oral suspensions. Dosages of Pyrimethamine can vary depending on the specific condition being treated, as well as the age and weight of the patient.

While it is generally safe and well-tolerated by most patients, it may cause side effects in some people. These can include headaches, nausea, vomiting, and dizziness. it may also interact with other medications, so it is important to inform your doctor of any other drugs you are taking before beginning treatment with it.

Overall, it is an important medication in the treatment and prevention of malaria and other parasitic infections.

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as a supplier of Pyrimethamine powder , Xi'an Yihui has rich production experience and technical knowledge, high-quality products, flexible production capacity, and quality customer service, which can provide better support and service to customers.

if you need Pyrimethamine API , pls feel free to contact us any time. we will reply you asap.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937