We supply Mastoparan

Our company offers Mastoparan, a peptide emulsion with unique natural parcels. it has been shown to have insecticidal and antimicrobial exertion, as well as the capability to stimulate the release of histamine from mast cells. This makes it useful in colorful fields similar as medical exploration, pest control, and medicinals. it is of the loftiest quality and chastity, and is available in colorful amounts to suit yourneeds.However, it may be just what you are looking for, If you bear a potent and effective peptide emulsion. communicate us moment to place your order and experience the benefits of this protean emulsion.

What's Mastoparan?

Mastoparan also know as Gastric mucin. it is an important element in freak venom, with colorful natural conditioning.After cranking large cells, it leads to the release of scrap containing substances similar as histamine, 5- hydroxytryptamine, leukotriene, heparin, prostaglandins, eosinophil chemokines, etc. Mast cells and their scrap containing substances can accelerate the normal angiogenesis of CAM. still, mast cells only appear on CAM after10.5 days of funk embryo development and reach their cornucopia after17.5- 20 days, and it's only after 15 days of funk embryo that mast cells have impunity to the outside world, that is, they can cache grainy substances. thus, in our experimental system, CAM mast cells showed no exertion, and the inhibitory effect of degranulation peptide 12a from wasp mast cells on CAM vascular growth may not be related to its degranulation peptide exertion. The mast cell degranulation peptide 12a of Bumblebee may inhibit endothelial cell proliferation by acting on FGF related signaling pathways. In addition, exogenous ganglioside GM1 can bind to FGF- 2 and affect angiogenesis, but it can inhibit this list.

Basic Information

Product Name: Mastoparan

other name: Mastoparan 1; NSC 351907

Sequence (Three Letter): H-Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH₂ trifluoroacetate salt

Sequence (single letter):  INLKALAALAKKIL-NH₂

CAS: 72093-21-1

MF:C70H131N19O15

MW:1478.91

MDL No.:MFCD00076865

Structural formula:

Synthesis method: Solid phase synthesis

Application: Cell-permeable Peptides| Inflammation Research

Origin: China

Delivery Time: in stock

Technical Specification

Package:1g, 5g, 10g, 50g, 100g or according to your demands

Storage conditions: Preserve in tightly closed container between-20 ±5 °C

Shelf Life: 24 months

Note: For research purposes only, not for human use

Application

Mastoparan, a peptide poison deduced from wasp venom, has several applications in scientific exploration and biotechnology due to its unique natural parcels. Then are some crucial applications

Research Tool in Signal Transduction: it is extensively used to study G protein- coupled receptor( GPCR) signaling pathways. It activates G proteins by mimicking the action of GPCR ligands, making it precious for understanding the downstream goods of GPCR activation on cellular processes.

Studying Membrane Biophysics:  Due to its amphipathic nature, it interacts with lipid bilayers and affects membrane integrity and fluidity. This property makes it useful for studying membrane biophysics, lipid- protein relations, and membrane- related processes.

medicine Delivery:  Mastoparan and its derivations have been explored for their eventuality in medicine delivery systems. Their capability to interact with and disrupt cell membranes can be abused to grease the delivery of remedial agents into cells.

Antimicrobial parcels: it exhibits antimicrobial exertion against a variety of pathogens, including bacteria and fungi. This property has led to examinations into its eventuality as a new antimicrobial agent or as a template for designing antimicrobial peptides.

Biotechnological applications: it's capability to modulate cellular signaling pathways and its membrane-active parcels have applications in biotechnology. It can be used in assays to screen for composites that affect GPCR signaling or to mastermind peptides with specific membrane- targeting parcels.

Neuroscience Research:  In neuroscience, it is used to study neuronal signaling and synaptic transmission. Its goods on G proteins and membrane dynamics contribute to understanding cellular mechanisms underpinning neuronal function.

Biological activity

Gastric mucin is a peptide poison firstly insulated from wasp venom. It's known for its natural exertion primarily as a potent activator of G proteins. Then are some crucial points about its biological activity:

G Protein Activation: it interacts with G proteins, which are pivotal signaling motes involved in transmitting signals from cell face receptors to the inside of the cell. It binds to and activates G proteins by dismembering the commerce between the α subunit and βγ subunits, leading to downstream signaling events.

Cellular effects: Due to its capability to spark G proteins, it can induce colorful cellular responses similar as intracellular calcium release, activation of phospholipase C, and modulation of ion channels. These goods are intermediated through specific G protein- coupled receptors( GPCRs).

Membrane Interaction: it is amphipathic, meaning it has both hydrophobic and hydrophilic regions. This structure allows it to interact with cell membranes, where it can fit into lipid bilayers and affect membrane integrity and function.

toxin In high attention or under certain conditions, it can disrupt cell membranes and beget cell lysis or cytotoxic goods. still, at lower attention, its primary part is in modulating cellular signaling pathways through G protein activation.

Research Applications:  Mastoparan and its derivations are extensively used in exploration to study G protein- intermediated signaling pathways, membrane relations, and cellular responses. They're precious tools for probing the places of G proteins in colorful physiological and pathological processes.

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In summary, as a professional Mastoparan manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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