Melanotan I

CAS No: 75921-69-6 (free base)/1566590-77-9 (acetate)
Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Appearance:  White powder
Standard: Enterprise Standard
Supply Ability:5000g per month
Shelf Life: Two years
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
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Product Introduction

We supply Afamelanotide(Melanotan I)

We offer Afamelanotide, also known as Melanotan I, a synthetic peptide that stimulates melanin product in the skin. This product is generally used for tanning purposes and is particularly effective for individualities with fair skin that have difficulty achieving a tan through natural means. it has also been studied for its implicit remedial benefits, including the treatment of skin diseases similar as vitiligo and erythropoietic protoporphyria. Our product is of high quality and chastity, icing that guests admit the stylish results possible.

 

What's Afamelanotide(Melanotan I)?

Afamelanotide is a synthetic peptide that mimics the goods of the natural hormone nascence- melanocyte stimulating hormone( α- MSH) in the body. It's primarily used to stimulate the product of melanin, which is the color responsible for the color of our skin, hair, and eyes.

It has gained fashionability as a tanning agent among individualities who ask a darker skin color. Unlike traditional tanning styles, similar as sunbathing or inner tanning, it doesn't bear exposure to dangerous ultraviolet( UV) radiation that can increase the threat of skin cancer and unseasonable aging.

Indeed though it is primarily used for ornamental purposes, it has also shown eventuality in treating certain medical conditions. It has been set up to be effective in treating erythropoietic protoporphyria( EPP), a rare inheritable complaint that makes individualities extremely sensitive to sun. By adding the natural melanin product in the skin, it helps cover EPP cases from the painful and enervating symptoms associated with sun exposure.

product-602-479

Basic Information

Product Name: Melanotan I

Sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2

CAS: 75921-69-6

MF:C78H111N21O19

MW:1646.85

EINECS:211-519-9

MDL No.:MFCD00151715

Assay: 95%; 98.0% HPLC

Structural formula:

product-1-1

Origin: China

Application: Peptide

Delivery Time: in stock

 

Technical Specification

TEST

SPECIFICATION

RESULT

Appearance

White powder

Conform

Solubility

Soluble to 0.60 mg/ml in sterile water

Conform

Water Content (Karl Fischer)

≤ 8.0%

4.9%

Acetic Acid (By HPLC)

≤ 5.0%~12.0%

9.9%

Peptide Purity (By HPLC)

≥80.0%

99.86%

 

Related Substance

(By HPLC)

Total Impurities(%) ≤ 2.0%

0. 14%

Largest Single Impurity(%) ≤ 1.0%

0.06%

Assay

95.0 ~105.0%

99.15%

Conclusion

Qualified

Package: 1g;100g;1000g or according to your demands

Storage method: Freeze dry at -20 ℃ and store in a dark place

Note: For research purposes only, not for human use

Shelf Life 24 months

 

Biological Activity 

Melanotan I is a synthetic analogue of melanocyte- stimulating hormone( MSH) that has been developed with the thing of adding melanin product in the body. Melanin is the color that gives color to the skin, hair, and eyes, and it plays an important part in guarding the skin from the dangerous goods of the sun's ultraviolet shafts.

Its main natural exertion is to stimulate the product of melanin in melanocytes, the cells that are responsible for producing melanin. When it is fitted into the body, it binds to melanocortin receptors in the skin, cranking a signaling pathway that leads to the product of melanin. This results in darker skin, hair, and eyes, and can also give a defensive effect against sunburn and other forms of UV damage.

In addition to adding melanin product, it has also been shown to have a range of other natural conditioning, including appetite repression, increased libido, andanti-inflammatory goods. While these goods haven't been completely studied, they offer implicit benefits for those seeking to ameliorate their overall health and good.

Overall, the natural exertion is centered around its capability to stimulate melanin product in the body. This can have a range of benefits for individualities looking to darken their skin or cover against UV damage, as well as implicit benefits for overall health and good. It's important to note, still, that it has not been approved by the FDA for any medical use and should be used only under the guidance of a healthcare provider.

 

What is application 

Afamelanotide belongs to the nascence- MSH analogs family. it can be used to treat photodermatoses caused by erythropoietic protoporphyria.

Melanotan-1( MT-I) is a synthetic analogue of nascence- melanocyte stimulating hormone( α- MSH) and has been set up to have photoprotective parcels. It stimulates melanin product in the skin, which can help reduce perceptivity to sun and UV radiation. it is presently used as a treatment for photodermatoses caused by erythropoietic protoporphyria, a inheritable complaint where the body is unfit to duly produce brim, a protein essential for the conformation of hemoglobin.

Clinical trials have shown that it can significantly reduce the symptoms of erythropoietic protoporphyria, including photosensitivity, pain, and discomfort. It has also been set up to ameliorate quality of life for cases with this condition. it is administered via injection and is generally well- permitted, with minimum side goods reported in clinical studies.

it may also have implicit operations in other areas, similar as treating skin diseases, promoting tanning, and enhancing sexual function. still, farther exploration is demanded to completely understand the safety and efficacity of these implicit uses.

Overall, it is a promising treatment option for individualities with photodermatoses caused by erythropoietic protoporphyria. Its capability to stimulate melanin product and reduce perceptivity to sun makes it a precious tool in managing the symptoms of this condition.

 

Melanotan I vs Melanotan II

Melanotan I and Melanotan II are both synthetic peptides that are used to stimulate melanin product in the skin. Here's a comparison of the two:

Aspect

Melanotan I

Melanotan II

Structure

Linear peptide

Cyclic peptide

Synthesis

13 amino acids

7 amino acids

Potency

Less potent

More potent

Melanin Stimulation

Slow, gradual tan development

Rapid, darker tan development

Side Effects

Fewer side effects

More side effects (including nausea, flushing)

Libido Enhancement

Minimal or none

Often reported libido enhancement

Appetite Suppression

Minimal or none

Often reported appetite suppression

In summary, Melanotan II is generally considered more potent and induces a darker tan more fleetly than Melanotan I. still, it also tends to have further side goods, including nausea and flushing. also, Melanotan II is occasionally associated with increased libido and appetite repression, which may not be present with MT-I.

 

Where to buy 

Xi'an Yihui company as a professional Melanotan I produced manufacturer, has strong technical strength and advanced production equipment, and is committed to providing customers with high-quality, efficient, and reliable raw materials.

if you need it, pls feel free to contact us at any time. we will reply you asap.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240

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