Sulfasalazine powder
Appearance: Bright Yellow or Brownish-Yellow,Fine Powder
Supply Ability:10000kg per month
Purity: ≥99%
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Can't sell to individuals
- Fast Delievery
- Quality Assurance
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Product Introduction
We supply Sulfasalazine powder
Our company is pleased to offer high- quality Sulfasalazine powder. This drug is constantly used to treat seditious bowel complaint, rheumatoid arthritis, and other autoimmune conditions. It is available in bulk amounts and is manufactured to strict quality control norms to insure chastity, thickness, and energy. Our educated platoon is devoted to furnishing excellent client service and icing prompt delivery to our guests around the world. Please communicate us for further information about our Sulfasalazine and to place an order moment.
What's Sulfasalazine API?
Sulfasalazine API is a pharmaceutical emulsion used substantially in the treatment of autoimmune conditions similar as rheumatoid arthritis and Crohn's complaint. It's an active component that's generally formulated into tablets, capsules, or dormancies.
It is a combination of two motes, sulfapyridine and 5- aminisalicylic acid, which work synergistically to ply ananti-inflammatory effect on the gastrointestinal tract. Sulfapyridine acts as a folate antagonist and inhibits the conflation of DNA, RNA, and proteins in bacteria. 5- aminisalicylic acid, on the other hand, is allowed to work by scavenging free revolutionaries and inhibiting colorful seditious intercessors similar as cytokines and leukotrienes.
It is generally taken orally and is fleetly absorbed in the small intestine. It's also transported to the colon, where it exerts itsanti-inflammatory effect. The lozenge and duration of treatment vary depending on the condition being treated and the case's overall health.
It has been shown to be effective in controlling symptoms of rheumatoid arthritis and Crohn's complaint. It can also be used to treat ulcerative colitis, psoriatic arthritis, and ankylosing spondylitis. Despite its effectiveness, it may beget side goods similar as nausea, puking, diarrhea, abdominal pain, and headache.
In conclusion, sulfasalazine is a vital medicinal component that has been used successfully in the treatment of seditious conditions. Its medium of action, combined with its efficacity and safety profile, make it a precious treatment option for cases suffering from autoimmune conditions.
Basic Information
Product Name: Sulfasalazine
CAS: 599-79-1
MF:C18H14N4O5S
MW:398.39
EINECS:209-974-3
MDL No.:MFCD00057363
Structural formula:
Origin: China
Delivery Time: in stock
Technical Specification
Execute standard:USP |
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NO. |
Item |
Specification |
Result |
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1. |
Appearance |
Bright yellow or brownish-yellow, Odorless,fine powder |
Confirm |
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2. |
Identification |
Conform With monograph A.B |
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3. |
Solubility |
Soluble in aqueous solutions of alkali hydroxides;very slightly soluble in alcohol;practically insoluble in water,in ether,in chloform,and in benzene |
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4. |
Chromatographic purity |
Single impurity NMT2.0% |
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Total impurity NMT4.0% |
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5. |
Residual solvents |
Pyridine NMT200ppm |
No detected
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Toluene NMT890ppm |
No detected
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DMF NMT880ppm |
No detected
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6. |
Mesh number |
All through 80 |
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7. |
Bulk density |
--- |
0.38g/cc |
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8. |
Tapped density |
--- |
0.63g/cc |
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9. |
Melting point |
248-253℃ |
250.0-252.5℃ |
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10. |
Chloride |
NMT 0.014% |
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11. |
Sulphate |
NMT 0.04% |
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12. |
Heavy metals |
NMT 0.002% |
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13. |
Loss on drying |
NMT 1.0% |
0.55% |
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14. |
Residue on ignition |
NMT 0.5% |
0.09% |
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15. |
Assay |
97.0—101.5% |
99.08% |
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Conclusion: |
Comply with specification |
Package: 1kg or 25kg according to your demands
Storage: Preserve in tight,light-resistant containers in cool place
Shelf Life: 2 years
Function
Sulfasalazine powder serves several important functions in the treatment of specific medical conditions, primarily due to itsanti-inflammatory parcels. Then are its crucial functions
Anti-Inflammatory Action: Sulfasalazine reduces inflammation by inhibiting the product of seditious cytokines, helping to palliate symptoms associated with seditious conditions.
Immunomodulation: It modulates vulnerable system exertion, which is particularly salutary in autoimmune diseases like rheumatoid arthritis. This helps to reduce the hyperactive vulnerable response that contributes to common damage.
application of Ulcerative Colitis In gastrointestinal applications, it helps to induce and maintain absolution in ulcerative colitis by targeting inflammation in the intestinal filling.
Characteristic Relief: The API provides characteristic relief from pain, swelling, and discomfort associated with conditions like rheumatoid arthritis and ankylosing spondylitis.
Combination remedy: it can be used in combination with other specifics to enhance remedial goods, particularly in managing habitual seditious conditions.
Disease Progression Control : By reducing inflammation and vulnerable system exertion, sulfasalazine can help decelerate the progression of habitual conditions, contributing to long- term application strategies.
Overall, sulfasalazine is a pivotal element in the treatment protocols for colorful seditious and autoimmune conditions, abetting in symptom control and perfecting patient quality of life.
Application
Sulfasalazine API( Active Pharmaceutical component) is primarily employed in the pharmaceutical assiduity for the expression of specifics aimed at treating colorful seditious conditions. Then are the crucial applications
expression of Tablets and Capsules: Sulfasalazine is generally formulated into oral lozenge forms to treat conditions like rheumatoid arthritis and ulcerative colitis.
Treatment of seditious Bowel Disease: Sulfasalazine is effective in managing symptoms of ulcerative colitis and Crohn’s complaint by reducing inflammation in the gastrointestinal tract.
application of Autoimmune conditions: It's used in the treatment of rheumatoid arthritis, helping to control symptoms and ameliorate quality of life.
Research and Development: Sulfasalazine can be used in clinical studies for probing its efficacity in other seditious conditions or as part of combination curatives.
Pediatric phrasings It can also be used in phrasings designed for children with applicable dosing adaptations.
Quality Control and Manufacturing
When producing sulfasalazine API, adherence to Good Manufacturing Practices( GMP) is pivotal to insure chastity, energy, and safety of the final product.
Regulatory Considerations
Sulfasalazine API must meet specific nonsupervisory norms before being approved for use in pharmaceutical products, which includes stability testing and bioavailability assessments.
Biological activity
Sulfasalazine API exhibits several important natural conditioning, primarily due to itsanti-inflammatory and immunomodulatory parcels. Then are the crucial aspects of its natural exertion
Anti-Inflammatory goods: Sulfasalazine helps reduce inflammation in colorful apkins by inhibiting the release of seditious intercessors similar as prostaglandins and leukotrienes. This is particularly salutary in conditions like ulcerative colitis and rheumatoid arthritis.
Immunosuppressive Action: It modulates vulnerable system exertion, helping to drop the hyperactive vulnerable response seen in autoimmune conditions. This action contributes to reduced common damage and inflammation in conditions like rheumatoid arthritis.
Inhibition of Cytokine Production: Sulfasalazine may drop the product ofpro-inflammatory cytokines( e.g., TNF- nascence, IL- 1), which play a significant part in the seditious process.
Antioxidant Properties: Some studies suggest that sulfasalazine may have antioxidant goods, helping to reduce oxidative stress, which can contribute to towel damage in habitual seditious conditions.
Gut Health: In the gastrointestinal tract, sulfasalazine acts topically to reduce inflammation, promote mending of the intestinal filling, and help manage symptoms of seditious bowel conditions.
Impact on Gut Microbiota: There's substantiation that sulfasalazine may impact gut microbiota composition, potentially contributing to its remedial goods in seditious bowel complaint.
Overall, the natural exertion of sulfasalazine API is multifaceted, making it an effective treatment option for colorful seditious and autoimmune diseases. Its capability to modulate inflammation and vulnerable responses plays a pivotal part in managing these conditions and perfecting patient issues.
Packing & Shipping
Packing:1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.
Customization:
Customized logo
Customized packaging
Graphic customization
Shipping:
Item |
Quantity |
ETA time |
Shipping Method |
By Courier |
≤50kg |
7-15days |
Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air |
50kg~200kg |
3-5days |
Fast and cheap |
By Sea |
Large quantity |
20-35days |
Cheapest way |
Payment Term
Why Choose Xi'an Yihui?
Customer feedback
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Contact Yihui
In summary, as a professional Sulfasalazine powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.
our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937
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