We supply Finasteride

We're proud to offer high- quality Finasteride powder. This product has been manufactured with the utmost care, using only the purest constituents to insure its efficacity and safety. Finasteride is a popular treatment for manly pattern hair loss, and is also used to treat benign prostatic hyperplasia( BPH). it is lab- tested and certified to give the loftiest possible chastity and energy, so you can be sure you are getting the stylish possible product.However, try it moment, If you are looking for a dependable and effective result to hair loss or BPH.

What is Finasteride API?

Finasteride API, also known as Finasteride Active Pharmaceutical component, is a drug used to treat enlarged prostate and manly pattern baldness. It's a type II 5α- reductase asset that targets the enzyme responsible for converting testosterone to dihydrotestosterone( DHT), a hormone that contributes to prostate growth and manly pattern baldness.

This API is a white crystallinepowder that's undoable in water but answerable in organic detergents. It's a tradition-only drug and should only be worn under the supervision of a good healthcare professional.

It is generally used to treat urinary symptoms caused by benign prostatic hyperplasia( BPH). This condition causes the prostate gland to come enlarged, leading to difficulties with urination. By inhibiting the product of DHT, it can reduce the size of the prostate gland, relieve urinary symptoms, and ameliorate the inflow of urine. it is also used to treat manly pattern baldness( androgenetic alopecia).

This condition is caused by a inheritable predilection and the hormone DHT, which contributes to the shortening of the hair growth cycle and the eventual miniaturization of hair follicles.By blocking the product of DHT, it can decelerate or indeed reverse baldness in men.

In addition to its primary uses, it has also been shown to have implicit benefits in treating other medical conditions, similar as hirsutism( inordinate hair growth), polycystic ovary pattern( PCOS), and prostate cancer.

It's worth noting that it may beget side goods in some druggies. These can include dropped libido, erectile dysfunction, and a rare but serious condition known aspost-finasteride pattern( PFS). People who witness any unusual or concerning symptoms should consult their healthcare provider incontinently.

Overall, Finasteride is a potent drug that offers significant benefits for people with BPH or manly pattern baldness. still, it should only be used under the advice and supervision of a good healthcare professional.

Basic Information

Product Name: Finasteride

CAS: 98319-26-7

MF:C23H36N2O2

MW:372.54

EINECS:620-534-3

MDL No.:MFCD00869737

Melting point: 253 °C

Structural formula:

Origin: China

Delivery Time: in stock

Chemical property:

White or off white crystalline solid.

Easy to dissolve in chloroform, dimethyl sulfoxide, ethanol, methanol or n-propanol, difficult to dissolve in propylene glycol or polyethylene glycol 400, extremely slightly soluble in 0.1mol/L hydrochloric acid, 0.1mol/L sodium hydroxide solution or water.

The melting point is about 257 ℃; There is also a melting point of 252-254 ℃. [α] D-59° (C=l, methanol).

Technical Specification

Package: 1kg; 25kgor according to your demands

Storage:Preserve in tight containers, and store at controlled room temperature.

Shelf Life:Powder:2 years

Product Usage

Treatment of benign prostatic hyperplasia

Finasteride powder is a introductory medicine used in the treatment of benign prostatic hyperplasia and prostatitis in China. It's a synthetic 4- androsteroid hormone emulsion and a resistance hormone medicine. It can widely inhibit 5 α- reductase, inhibit the conversion of testosterone to 5 α- dihydrotestosterone( DHT), reduce the position of testosterone in prostate cells, drop the prostate-specific antigen in serum, shrink the enlarged prostate volume, increase urinary inflow rate, thereby easing patient symptoms and achieving the thing of treating benign prostatic hyperplasia. The specific of this medicine is that it can widely block the stimulating effect of androgens on the prostate, but it infrequently affects manly sexual function.

Prostate hyperplasia, also known as prostate blowup, causes contraction of the bladder neck and posterior urethra, leading to urinary tract inhibition and other symptoms and complications, causing great pain to cases. It's more common in manly populations over 50 times old.

specifics for treating manly type hair loss

Finasteride is also a specific asset of 5 α- reductase and belongs to the resistance hormone class. It can help testosterone from being converted to dihydrotestosterone, thereby reducing the conflation of dihydrotestosterone, lowering the situations of dihydrotestosterone in crown hair follicles and serum, restoring the hair follicle papilla function that has been inhibited, promoting hair growth, and precluding farther hair loss. Finasteride is presently the only oral drug approved by the US Food and Drug Administration( FDA) for the treatment of manly type hair loss, with a recommended cure of 1 mg per cure.

Production method

Using pregnenolone as the raw material. First, reply with pyridine, and also reply with sodium methoxide to gain 3- hydroxy-5-androstene-17 β- carboxylic acid methyl ester( III). Influx with aluminum isopropoxide in toluene and cyclohexanone. Sludge, marshland, dry, and concentrate under reduced pressure. Add petroleum ether, stir at 5 ℃, and sludge to gain the oxidized product( IV) with a yield of 74.6%. The oxidation product is refluxed with 95% ethanol and 10% potassium hydroxide result under nitrogen protection. After reducing pressure and sinking ethanol, acclimate the pH value to about 3 with 6mol hydrochloric acid. Sludge by suction, wash the sludge cutlet with water until neutral, and dry to gain the hydrolysis product( V) with a yield of 96.4%. The hydrolysis product is dissolved in tert butanol, and an waterless result of anhydrous sodium carbonate is added while stirring. also, an waterless result of sodium periodate and potassium permanganate is added dropwise under influx, and the admixture is refluxed after completion. Cooling and filtering. After reducing the pressure and sinking utmost of the tert butanol from the filtrate, acclimate the pH value to about 2 with 6mol/ L hydrochloric acid in an ice bath. prize with ethyl acetate, wash the excerpt with impregnated sodium chloride, and dry. The product( VI) was attained by vacuum evaporation and recrystallization of ethyl acetate, with a yield of 66. Under ice bath cooling, ammonia gas is introduced into ethylene glycol, and ring opening products are added. The response is sluggishly raised to 180 ℃. Cool down, add water, use 6mol/ I. Acclimate hydrochloric acid to a pH value of roughly 2. Filter the solid, wash with water until neutral, and recrystallize from dimethylformamide to gain the cyclic product( VII) with a yield of 62.1%. The cyclic product is hydrogenated with platinum dioxide, acetic acid, and a small quantum of perchloric acid at 85 ℃ and atmospheric pressure. After filtering out the catalyst, concentrate under reduced pressure to blankness. The residue was recrystallized from dimethylformamide to gain hydrogenated product( VIII) with a yield of 92.9%. The hydrogenated product is mixed with triphenylphosphine, toluene, and 2,2'- bipyridine disulfide( DPDS) and stirred at room temperature. Pyridine sulfide( IX) was insulated by column chromatography with a yield of 79.0%. The sulfide was mixed with anhydrous tetrahydrofuran and tert butylamine at room temperature overnight, dichloromethane was added, washed with 2mol/ L hydrochloric acid and impregnated sodium chloride, dried, and concentrated under reduced pressure. The residue was recrystallized from ethyl acetate to gain the amide product( X) with a yield of 77.1%. The amide is refluxed with phenylselenide anhydride and chlorobenzene, and the detergent and generated water are sluggishly faded. Column chromatography separation was performed, and the crude product was recrystallized from ethyl acetate to gain white finasteride chargers with a yield of 52.3% and a melting point of 253- 255 ℃.

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Yihui takes pride in being a trusted Finasteride powder manufacturer and supplier. To acquire this groundbreaking product or discuss your specific requirements, contact us immediately at sales@yihuipharm.com. Rest assured, with Yihui, you're accessing a product of unparalleled quality, backed by certifications that underscore our commitment to excellence in the global market.