We supply Promethazine hydrochloride API

We offer Promethazine hydrochloride API, which is a medicine used to treat various antipathetic responses, stir sickness, and nausea. This API works by blocking certain natural substances in the body that can beget analogous responses. It's a largely effective drug that is safe to use and available in both tablet and injection forms. Promethazine hcl API is considerably used in the pharmaceutical sedulity to manufacture a variety ofanti- mislike andanti- nausea specifics. Our API is of the topmost quality and chastity, and we flatter ourselves on delivering it snappily and efficiently.

What's Promethazine hydrochloride?

Promethazine hydrochloride powder is an organic conflation with the chemical formula C17H20ClN2S. It's an antihistamine drug that competitively blocks the histamine H1 receptor, counteracts capillary dilation caused by histamine, and reduces its permeability. it is the foremost discovered tricyclic antihistamine with a phenothiazine like structure, which has cough relieving goods. It can competitively block the histamine H1 receptor and produce antihistamine goods, neutralize capillary dilation caused by histamine, and reduce its permeability. therefore, it can palliate coughing caused by tracheal vexation.

Basic Information

Product Name: Promethazine hydrochloride

CAS:58-33-3

MF:C17H21ClN2S

MW:320.88

EINECS:200-375-2

MDL No.:MFCD00012652

Structural formula:

Purity: 99%+

Origin: China

Application: antihistamine

Delivery Time: stock

Technical Specification:

Package: 1kg; 25kg or according to your demands

Storage conditions: keep tightly closed, store in a cool dry place.

Application

Promethazine hydrochloride API, generally used as an antihistamine and antiemetic medicine, finds operation in various pharmaceutical phrasings. also are some pivotal uses

Antipathetic Conditions It's used to relieve symptoms of antipathetic responses analogous as itching, rash, and watery nose.

stir Sickness: it helps in preventing and treating stir sickness by reducing nausea and vomiting.

Sedation: Due to its comforting goods, it's used in preoperative sedation and to manage anxiety.

Antiemetic It effectively controls nausea and puking associated with surgery, chemotherapy, or radiation remedy.

Adjunct to Analgesics sometimes used in combination with anesthetics to enhance pain relief and reduce associated nausea.

Insomnia In some cases, it can be used to prop sleep due to its comforting parcels.

Adjunct in Anaphylaxis In emergency settings, it may be used as an spare treatment for anaphylaxis, though this is less common.

When using Promethazine hydrochloride, it's vital to stick to specified tablets and guidelines due to its implicit drowsy goods and the trouble of side goods analogous as drowsiness, dry mouth, and blurred vision.

Pharmacokinetics

After oral or injection administration, the absorption is fast and complete, and the protein list rate is high. The effective time of this product after oral or rectal administration is 20 beats. The antihistamine effect generally lasts for 6- 12 hours, and the comforting effect can last for 2- 8 hours. mainly metabolized in the liver, inactive metabolites can be excreted through urine, with a small amount excreted through feces. Pharmacological goods Promethazine hydrochloride powder is a phenothiazine antihistamine, which can also be used for antiemetic, anti stir, anesthetic, and narcotic purposes.

1. Anti histamine effect Competes with histamine released by apkins for H1 receptors, can antagonize histamine's contraction or contraction of smooth muscles in the gastrointestinal tract, trachea, bronchi, or bronchioles, and relieve histamine's spasmodic and congestive goods on bronchial smooth muscles.

2. Antiemetic effect may be related to the inhibition of the chemosensory area of the medulla oblongata that induces puking.

3. Anti stir sickness: Promethazine hcl API may act on the vestibular and puking centers, as well as the midbrain medullary receptors through central anticholinergic parcels, mainly blocking the excitation of cholinergic synaptic complicate impulses in the vestibular nexus.

4. Sedative and narcotic goods may be due to indirectly reducing the stress- induced activation of the brainstem reticular thrusting system.

Indications

1. aversions to skin and mucous membranes Suitable for long- term and seasonal antipathetic rhinitis, vasoconstrictive rhinitis, antipathetic conjunctivitis caused by contact with allergens or food, urticaria, angioneurotic edema, antipathetic responses to blood or tube products, and skin scrape pattern. When necessary, it can be used in combination with adrenaline as an adjuvant for this drug.

2. stir sickness prevention and treatment of stir sickness, sickness, and nausea.

3. Sedation and mesmerism suitable for preoperative, postoperative, and obstetric use. In addition, it can also be used to palliate fear in grown- ups and children, and maintain a light sleep state.

4. Treatment of nausea and gagging Suitable for some anesthesia and postoperative nausea and vomiting, as well as for the prevention and treatment of radiation induced or drug- induced nausea and vomiting.

5. Postoperative pain It can be used in combination with anodynes as an adjuvant medicine.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.

Customization:Customized logo;Customized packaging;Graphic customization

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As a professional Promethazine hydrochloride powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com

Tel: 0086-29-89695240
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