We supply Epirubicin Hydrochloride

Our company is proud to offer high- quality Epirubicin Hydrochloride. This potentanti-cancer medicine is extensively used in chemotherapy treatments, and we insure that our product is of the loftiest chastity and quality to support the important work of medical professionals. it is known for its capability to inhibit DNA conflation and beget cell death in cancer cells. Our API is available in colorful forms and packaging sizes to meet your specific requirements. With our commitment to excellence, you can trust that our product will help you in producing safe and effective treatments for your cases.

What's Epirubicin HCL?

Epirubicin hcl is the main isomer of doxorubicin, which is the trans configuration of the C4 hydroxyl group in the aminoglycoside of doxorubicin. It can be directly bedded in DNA, form complexes with the double helix structure of DNA, block RNA conformation dependent on DNA, and have the kinetic energy to form superoxide revolutionaries. Single medicine has broad- diapason inhibitory effect on a variety of excrescences, including bone cancer, nasty carcinoma, soft towel sarcoma and gastric cancer. Research has shown that the medicine also hasanti-tumor exertion against nasty carcinoma and colon cancer.

Basic Information

Product Name: Epirubicin hydrochloride

CAS: 56390-09-1

MF:C27H30ClNO11

MW:579.9802

EINECS:260-145-2

MDL No.:MFCD00274554

Structural formula:

Origin: China

Delivery Time: in stock

Application: Antitumor

Melting point: 185 ° Cdec

Specific rotation: D20+274 ° (c=0.01inmetanol)

RTECS number: QI9295750

Flash point: 443.8 ℃

Storage conditions: Inertatmosphere, Storeinfilter, under-20 ° C

Solubility: soluble in DMSO to 100mM, or soluble in ethanol to 10mM

Stability: Stable for 2 years from the date of purchase. DMSO or distilled water solutions can be stored at -20 ℃ for up to 3 months.

Technical Specification

Package: 10g;100g or according to your demands

Storage conditions: Preserve in tightly closed container at controlled room temperature.

Transportation conditions Transportation at room temperature

Shelf Life 24 months

Application:

Epirubicin hydrochloride is an anthracycline antibiotic generally used as a chemotherapy agent. It's primarily employed for its potentanti-tumor exertion in colorful types of cancer. Then are its crucial applications:

Breast Cancer:

Adjuvant: remedy it is frequently used as part of adjuvant remedy in early- stage bone cancer to reduce the threat of cancer rush following surgery.

Metastatic bone Cancer: It's also employed in treating advanced or metastatic bone cancer, either alone or in combination with other chemotherapeutic agents.

Ovarian Cancer:

it is used in the treatment of advanced ovarian cancer, frequently in combination with other medicines to enhance remedial efficacity.

Gastric Cancer:

It's employed in the application of advanced gastric cancer( stomach cancer), generally as part of combination chemotherapy rules.

Lung Cancer:

it is occasionally included in treatment protocols for small cell lung cancer andnon-small cell lung cancer, particularly in cases where other treatments haven't been effective.

Lymphomas:

The medicine is used in certain types of tubercles, includingnon-Hodgkin carcinoma, as part of combined chemotherapy protocols.

Bladder Cancer

it can be administered intravesically( directly into the bladder) as part of the treatment for superficial bladder cancer to help rush after surgical resection.

Soft Towel Sarcomas

It's employed in treating colorful soft towel sarcomas, either as a single agent or in combination with other chemotherapies.

Clinical application

It's extensively used clinically and is substantially used to treat colorful solid excrescences similar as acute leukemia and nasty carcinoma, bone cancer, bronchial lung cancer, ovarian cancer, nephroblastoma, soft towel sarcoma, bladder cancer cancer, testicular cancer, prostate cancer, gastric cancer, liver cancer( including primary hepatocellular melanoma and metastatic cancer), and medullary thyroid cancer.

Pharmacological action

Epirubicin hcl is the main isomer of doxorubicin, which is the trans configuration of the C4 hydroxyl group in the aminoglycan half of doxorubicin. Its main medium of action is to directly fit into conterminous base dyads of DNA, form reversible list with DNA double helix, intrude with recap process, thereby inhibiting DNA and RNA conflation, and achieving the thing of treating excrescences. In addition, it has an inhibitory effect on topoisomerase II, can also act on the nexus, and can affect the cell membrane and its transport system of excrescence cells. It's anon-specific medicine for the cell cycle and is effective against colorful transplant excrescences.

Pharmacokinetics

The towel distribution of this product is analogous to that of doxorubicin. After 1 hour, 24 hours, and 48 hours of administration, the attention in the heart and spleen, as well as in the feathers after 48 hours, is lower than that of doxorubicin. At 24 and 48 hours, the attention in the excrescence was significantly lower than that of doxorubicin. The half- life of tube is 30 hours, substantially excreted through the biliary tract. 10 is excreted in urine at 48 hours, and 40 is excreted within 4 days. The vast maturity is excreted in its original form and in combination with glucuronic acid.

Medicine relations

1. It has synergistic goods and toxin with otheranti-cancer medicines, and should avoid contact with each other or be administered in the same vessel. When used in combination, the lozenge should be reduced.

2. Avoid using gratuitous medicines that may beget liver, order, or heart damage together.

3. This product suppresses vulnerable responses and shouldn't be used together with live vaccines.

4. casket radiation remedy can complicate the myocardial damage of this drug.

5. The lozenge should be meetly reduced when used in combination with severe bone gist repression of nitrosamines and mitomycin

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.

Customization:Customized logo;Customized packaging;Graphic customization

Shipping:

Lead time: Within 3 workdays after receiving payment.

Payment Term

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In summary, as a professional Epirubicin hydrochloride manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Dactinomycin stand out in the market competition and win more customer trust and support. if you need Epirubicin hcl, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937