We supply Letrozole powder

We're a leading supplier of Letrozole powder, a largely potent medicine used in the treatment of estrogen-dependent bone cancer in postmenopausal women. As an aromatase asset, it works by blocking the enzyme responsible for converting androgens to estrogens, thereby reducing the position of estrogen in the body and hindering the growth of cancer cells.

Our products is manufactured under strict quality control measures and meets transnational norms. We insure timely delivery and offer competitive pricing to our valued guests. communicate us to bandy how we can meet your specific requirements for Letrozole.

What's Letrozole powder?

Letrozole powder is a new generation of largely picky aromatase impediments, which are instinctively synthesized benzyltriazole derivations. By inhibiting aromatase, estrogen situations drop, thereby barring the stimulating effect of estrogen on excrescence growth. The in vivo exertion is 150- 250 times stronger than the first generation aromatase asset expression Amglutide. Due to its high selectivity, it doesn't affect glucocorticoids, mineralocorticoids, and thyroid function. High cure use has no inhibitory effect on the stashing of adrenal corticosteroids, thus it has a high remedial indicator.

Letrozole API is substantially used in postmenopausal cases with estrogen receptor( ER/ PR positive) positive bone cancer. bone cancer is related to estrogen. The estrogen of premenopausal women substantially comes from the ovary. After menopause, it's substantially converted from androgen to estrogen, and the androgen is converted into estrogen through chemoalbook, which is substantially converted through an enzyme- aromatase. It reduces estrogen by inhibiting this enzyme. Simply put, it's a" big gate" medicine that inhibits estrogen conversion in postmenopausal women.

Basic Information

Product Name: Letrozole

CAS:112809-51-5

MF:C17H11N5

MW:285.3

EINECS:675-034-8

MDL No.:MFCD00866241

Structural formula:

Purity: 99%+

Origin: China

Application: Anti-cancer

Delivery Time: stock

Melting point: 181-183 ° C

Boiling point: 563.5 ± 60.0 ° C (Predicted)

Density: 1.21 ± 0.1 g/cm3 (Predicted)

Solubility: dimethyl sulfoxide:>50mg/mL

Technical Specification:

Package: 100g; 500g; 1kg

Storage conditions: Keep in dark place, Inert atmosphere,2-8°C

Safety Information

Dangerous goods label: Xi

Hazard category code: 36/37/38

Safety instructions: 26-36

WGK Germany: 3

RTECS number: DI4957000

Customs code: 2933997500

Toxic Substances Data: 112809-51-5(Hazardous Substances Data)

Hazard description: H361fd-H373

Prevention instructions: P202-P260-P280-P308+P313-P405-P501

What is the Pharmacological action of Letrozole API?

Letrozole API is a potent oral medication used for the treatment of breast cancer that is hormone receptor-positive, in postmenopausal women. This drug belongs to a class of drugs known as aromatase inhibitors, which are known for their anti-cancer effects.

It works by inhibiting the activity of aromatase, which is an enzyme responsible for converting adrenal androgens to estrogens in postmenopausal women. By inhibiting aromatase,it helps to reduce the amount of estrogen present in the body, thereby slowing the growth and spread of hormone receptor-positive breast cancer cells.

It has been clinically proven to improve outcomes in women with breast cancer, particularly when used as part of a comprehensive treatment strategy. This medication has been shown to reduce the risk of breast cancer recurrence, and can also improve overall survival rates in women with advanced breast cancer.

It is a highly effective and well-tolerated drug, with a low risk of side effects. Common side effects may include hot flashes, joint pain, fatigue, and nausea. In rare cases, more serious side effects such as bone fractures, high blood pressure, or liver problems may occur.

Overall, Letrozole is an important treatment option for women with hormone receptor-positive breast cancer. This medication offers a promising alternative to traditional chemotherapy and can provide a better quality of life for patients undergoing treatment for breast cancer.

What is the application of Letrozole API?

Letrozole powder is an advanced pharmaceutical ingredient that is widely used in the medical industry. This product is known for its excellent medicinal properties and is used in the treatment of breast cancer. It belongs to the class of drugs called aromatase inhibitors, which work by blocking the production of estrogen in the body.

1. Treatment of postmenopausal advanced breast cancer (those with estrogen receptor, progesterone receptor positive or those with unknown receptor status), mostly for second-line treatment after failure of anti estrogen treatment;

2. For first-line treatment of locally advanced or diffuse postmenopausal breast cancer (foreign data);

3. Extended adjuvant therapy for postmenopausal breast cancer patients who have received tamoxifen standard adjuvant therapy for 5 years (foreign data);

4. It is used for postoperative adjuvant treatment of hormone positive early breast cancer patients.

Reference materials

1. Letrozole. Medical Encyclopedia [citation date 2017-05-7]

2. Letrozole. Huayuanwang [Cited on February 16, 2023]

3. Chinese Pharmacopoeia Commission. Pharmacopoeia of the People's Republic of China (Part II). China Medical Science and Technology Press. 2020. P568

Contact information

as a professional Letrozole powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Letrozole API stand out in the market competition and win more customer trust and support. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937