Sodium Fusidate powder

CAS No: 751-94-0
Appearance: White or almost white crystalline powder
Standard: EP
Supply Ability: 1000kg per month
Shelf Life: Two years
Application: Antibacterial Raw Material
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
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Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
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Product Introduction

We supply Sodium Fusidate powder

We offer high- quality sodium fusidate powder, a drug used to treat bacterial infections. Our Sodium Fusidate is manufactured through a strict process to insure high chastity and efficacity. It works by stopping the growth and spread of bacteria, making it an effective treatment for colorful types of infections. Our product is available in different amounts to suit your requirements. Whether you are a pharmaceutical company or a manufacturer of topical results, we can give you with the right quantum of Sodium Fusidate. communicate us moment to learn further about our product and how we can meet your requirements.

 

What is Sodium Fusidate powder?

Sodium Fusidate powder, also known as Fusidic acid sodium salt, is a narrow diapason antibiotic with a steroid backbone. It's a outgrowth of fusidic acid and appears as a white crystalline or crystalline greasepaint. It's odorless, bitter in taste, slightly hygroscopic, fluently answerable in water and ethanol, slightly answerable in chloroform, and undoable in bobby acetate, ether, and benzene. Developed for the first time by Danish pharmaceutical company Leopold, the product is known as risperidin. It has strong towel permeability and is substantially metabolized in the liver, but is excreted by corrosiveness and nearly not through the feathers. It has low toxin and produces bactericidal goods by inhibiting bacterial protein conflation. It has good antibacterial goods on gram-positive bacteria and has good resistance. At the same time, strains resistant to antibiotics similar as penicillin and methicillin are still sensitive to this product. There's no cross resistance between fusidate sodium and other clinically used antibiotics. This product is a non cephalosporin antibiotic and thus doesn't bear skin mislike testing. presently, it's extensively used in clinical practice to treat colorful infections caused by sensitive bacteria, especially Staphylococcus, similar as osteomyelitis, sepsis, endocarditis, intermittent cystic fibrosis, bacterial endocarditis, pneumonia, meningitis, diphtheria, tuberculosis, skin and soft towel infections, surgical and traumatic infections, etc. Intravenous administration is used for severe infections or medicine- resistant strains, as well as MRSA infections. still, due to its vulnerability to medicine resistance, it's frequently used as an adjuvant drug. Oral treatment of pseudomembranous colitis caused by Clostridium difficile is effective.

 

Basic Information

Product Name: Sodium fusidate

CAS NO.: 751-94-0

MF: C31H49NaO6

MW: 540.72

EINECS: 212-030-3

MDL No.: MFCD00865135

Purity: 99%+

MOQ: 1kg

Origin: China

Application: Antibacterial

Structural formula:

product-1-1

Technical Specification:

Items

Specifications

Results

Appearance

White or almost white crystalline powder, slightly hygroscopic. Freely soluble in water and 96%ethanol.

White crystalline powder, slightly hygroscopic.

Identification

A:The IR spectrum should be identical with the sodium fusidate CRS.

Conforms

B: The residue shows reaction of sodium salts.

Conforms

Appearance of solution

The color of solution is not more than reference solution B6

Conforms

PH

7.5~9.0

8.9

Related substances

Impurity A: NMT 0.3%

ND

Impurity B: NMT 0.4%

ND

Impurity C: NMT 0.2%

ND

Impurity D: NMT 0.2%

ND

Impurity N: NMT 0.2%

0.02%

Impurity F: NMT 0.2%

ND

Impurity G: NMT 0.7%

0.07%

Impurity I: NMT 0.2%

ND

Impurity K: NMT 0.2%

ND

Impurity L: NMT 0.5%

ND

Impurity M: NMT 1.0%

0.12%

Any other impurity: NMT 0.10%

ND

Total impurities: NMT 2.0%

0.23%

Water

NMT 2.0%

1.4%

Assay(on drying basis)

97.5%~101.0%

99.7%

Residual solvents

Ethanol NMT 5000ppm

ND

Acetone NMT 5000ppm

770ppm

Conclusion: the goods conforms the standard of EP.

Package: 1kg/bag; 25kg/drum

Storage conditions: Keep in dark place, Inert atmosphere, 2-8°C


Safety Information

Dangerous goods labeling: Xn, Xi

Hazard category code: 22-36/37/38

Safety instructions: 26-36

WGK Germany: 3

RTECS number: LV5775000

Customs code: 29419000

Toxicity: LD50inmice(g/kg):0.2i.v.(Godtfredsen,Nature1962)

 

Biological activity

Fusidate Sodium is the sodium salt form of fusidic acid, an antibacterial antibiotic derived from Fusarium oxysporum, used as a local drug for the treatment of skin infections.

 

In vivo research

Fusidate Sodium can improve experimental autoimmune myocarditis by inhibiting the secretion of TNF-a. It can attenuate t Sodium Fusidate he clinical and histological characteristics of immunoinflammatory diabetes in mice treated with streptozotocin (SZ). This effect was found to be dose-dependent in three different strains of mice. Therefore, fusidin may have anti diabetes effect.

 

What is the application of Sodium Fusidate powder?

Sodium fusidate powder has a bactericidal effect by inhibiting bacterial protein synthesis, and has a strong antibacterial effect on a range of Gram positive bacteria. Staphylococcus, including strains resistant to penicillin, methicillin, and other antibiotics, are highly sensitive to this product. There is no cross resistance between fusidate sodium and other antibiotics used in clinical practice

As an antibiotic with a steroid backbone, it mainly has antibacterial effects against Gram positive bacteria, Neisseria and Mycobacterium tuberculosis. Used for peripheral infections caused by sensitive bacteria, especially suitable for strains resistant to other antibiotics. Commonly used for infections in skin, bone tissue, joints, and other areas, as well as endocarditis

 

Contact Us:

Yihui Pharmaceuticals, as a professional Sodium fusidate powder manufacturer and supplier, is committed to delivering exceptional quality. Our adherence to international standards and prestigious certifications, including ISO, Kosher, Halal, and GMP, underscores our dedication to product excellence. For inquiries or to purchase Fusidic acid sodium salt, please contact us immediately at sales@yihuipharm.com. Choose Yihui Pharmaceuticals for unparalleled quality and reliability in every batch of Sodium fusidate.

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