Atipamezole HCL

CAS: 104075-48-1
Standard: in-house
Brand: YIHUI
Packing: 100g;1kg
Supply Ability: 20kg per month
Shelf Life: Two years
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse,1-3 days
Origin: China
Shipping: DHL,FedEx,TNT,EMS,By Sea,By Air
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Product Introduction

What is Atipamezole HCL?

Atipamezole HCl is a medication used in veterinary medicine. It belongs to the class of drugs known as alpha-2 adrenergic receptor antagonists or alpha-2 blockers. It is commonly used as a reversal agent for the effects of certain sedatives and anesthetics in animals.


Basic Information

Product Name: Atipamezole hydrochloride

CAS: 104075-48-1

MF:C14H16N2.HCl

MW:248.75

EINECS:105-700-9

MDL No.:MFCD06407819

Purity: 99%

Package: 10g;100g;1KG

Used: Pharma grade &Lab research

Stability: Stable

Structural formula:

104075-48-1.webp

Specifications and Parameters:

ITEMS   & RESULTS

SI.No.

Tests parameter

Specifications

Results

Conclusions

1

Appearance

White solid

White solid

Conform

2

Identification test

FT-IR: comparable to standard

Conform

Conform

3

Melting point

220℃~224℃

222.6-223.1

Conform


4


Impurities

Any individual

Impurities

≤0.5%

0.42

Conform

Total Impurities

≤1.0%

0.42

Conform

5

Loss on drying

≤0.5%

0.14%

Conform

6

Residue on ignition

≤0.5%

0.19%

Conform

7

Purity(HPLC)

≥98.5%

99.57%

Conform

8

pH

4~6

4.31

Conform

9

Solubility(1% solution

in water)

Colorless

Colorless

Conform

10

Total heavy metals     (Hg,As,Pb,Cd,Cr,Ni)

≤20ppm

Conform

Conform




11




Residual Solvents

Ethyl alcohol

<5000ppm

ND

Conform

THF

<720ppm

77.6ppm

Conform

Dichloromethane

<600ppm

5.24ppm

Conform

Ethyl acetate

<5000ppm

7.9ppm

Conform

Conclusion: Qualified


Chemical Composition:

Atipamezole hydrochloride has the chemical formula C14H17N3.HCl, with a molecular weight of 269.76 g/mol. This compound appears as white to off-white crystalline powder and exhibits high solubility in water.

Role and Function:

This kind of product, renowned for its efficacy, primarily functions as an alpha-2 adrenergic antagonist. Here are the critical jobs and elements of this product:

  • Inversion of Sedation: It is normally used to invert the calming impacts of alpha-2 adrenergic agonists, for example, medetomidine or dexmedetomidine. These medications are frequently used for sedation and anesthesia in animals. The product acts as an antagonist by binding to the alpha-2 adrenergic receptors, blocking the effects of the sedatives, and rapidly reversing sedation, allowing animals to regain consciousness.

  • Inversion of Absense of pain: It can also be used to reverse some medications' analgesic effects on alpha-2 adrenergic receptors. By blocking these receptors, it can help restore normal pain perception in animals after surgical procedures or other painful conditions.

  • Restoration of Physiological Functions: Atipamezole hydrochloride aids in restoring normal physiological functions in animals by antagonizing the effects of alpha-2 adrenergic agonists. It helps switch secondary effects like bradycardia (slow pulse), hypotension (low circulatory strain), and respiratory gloom brought about by these medications.

  • Emergency Treatment: It very well might be utilized as a crisis treatment for glut or unfriendly responses to alpha-2 adrenergic agonists. By rapidly reversing the effects of these medications, it can help stabilize animals and prevent potential complications.

In veterinary applications, it proves invaluable in the reversal of xylazine and medetomidine-induced sedation, providing a safer and more controlled environment for animals post-procedure.

Synthesis Process:

The union of the item includes a few meticulous advances. Beginning from forerunners with exact reactivity, the cycle incorporates buildup responses, sanitization steps, and exact crystallization to yield the end result. This guarantees the high immaculateness expected for drug applications.

Product Quality Standards:

Yihui upholds stringent quality standards in the production of Atipamezole. The manufacturing process is in strict accordance with international guidelines, guaranteeing a purity level of at least 99%. Yihui's commitment to quality is underscored by certifications such as ISO, Kosher, Halal, and GMP, reassuring clients of the product's reliability and adherence to global standards.

Application Fields in Various Industries:

The item tracks down assorted applications across enterprises, fundamentally succeeding in veterinary medication. Its utilization as an inversion specialist in sedation methodology for creatures is essential. Past veterinary applications, it has likely in drug innovative work, adding to progressions in narcotic pharmacology. There are the principal application fields of the item in different businesses:

  • Veterinary Medicine: Atipamezole HCL is extensively used in veterinary medicine as a reversal agent for alpha-2 adrenergic agonists such as medetomidine and dexmedetomidine. These medications are regularly utilized for sedation, sedation, and absense of pain in creatures. It plays a crucial role in rapidly reversing the sedative and analgesic effects, allowing animals to recover from anesthesia and regain consciousness.

  • Pharmaceutical Research and Development: It may be utilized in pharmaceutical research and development related to veterinary medicine. This could involve studies on dosage forms, pharmacokinetics, formulation development, and the development of new veterinary anesthesia and sedation protocols.

  • Biomedical Research: In the field of biomedical research, the 104075-48-1 may be employed in studies related to animal physiology, pharmacology, and anesthesia management. Researchers may use this compound to investigate the effects of sedative reversal and its impact on animal recovery and welfare.

  • Animal Husbandry and Zoological Institutions: It is relevant in animal husbandry and zoological settings where sedation and anesthesia are used for medical procedures, diagnostic imaging, or transportation of animals. Its role in quickly reversing sedation contributes to the safety and well-being of the animals involved.

OEM Services:

Yihui, as a leading manufacturer, extends OEM services, catering to the specific requirements of clients. With a commitment to flexibility and customization, Yihui ensures that the product aligns seamlessly with the unique needs of diverse industries.

Contact Us:

Yihui's dedication to quality, international standards, and certifications positions it as a trustworthy partner in the procurement of Atipamezole HCL. For inquiries and purchases, please contact Yihui immediately at sales@yihuipharm.com.

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