Acipimox powder

CAS: 51037-30-0
Appearance: White or light yellow powder or crystalline powder.
Standard: CP
Supply Ability: 1000kg per month
Shelf Life: Two years
Application: A new lipid-lowering drug with anti lipid-lowering properties
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Can't sell to individuals
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Product Introduction

What is Acipimox powder

Acipimox powder is a medication used to treat dyslipidemia, or abnormal levels of cholesterol and triglycerides in the blood. It is a type of medication called a niacin analogue, which means it works in a similar way to vitamin B3 (niacin) to lower cholesterol levels.

It is typically prescribed for people who have high levels of triglycerides and low levels of high-density lipoprotein (HDL) cholesterol. These conditions are associated with a higher risk of cardiovascular disease, including heart attack and stroke. By lowering triglyceride levels and raising HDL cholesterol levels, it can help reduce this risk.

It is usually taken orally, either as a tablet or a capsule. The dosage and frequency of use will depend on individual needs and medical history. It is important to follow all instructions provided by your healthcare provider, including any dietary or lifestyle modifications that may be recommended.

As with any medication, there are potential side effects associated with the use of Acipimox. These may include dizziness, nausea, vomiting, abdominal pain, headache, muscle pain, and skin rash. If you experience any of these symptoms, or any other unusual symptoms while taking it, it is important to speak with your healthcare provider right away.

In summary, it is a medication used to treat dyslipidemia and reduce the risk of cardiovascular disease. It is a type of niacin analogue that works by lowering triglyceride levels and raising HDL cholesterol levels. If you have been prescribed it, it is important to follow all instructions provided by your healthcare provider and be aware of potential side effects.

 

Basic Information

Product Name: Acipimox

CAS: 51037-30-0

MF: C6H6N2O3

MW: 154.12

EINECS: 256-928-3

MDL No.:MFCD00865757

Purity: 99%+

Package: 1kg; 25kg

MOQ: 1KG

Origin: China

Package: 1kg; 25kg

Used: API

Stability: Stable

Delivery Time: 3-7days

Structural formula:

product-1-1

 

Technical Specification:

Items

Specification

Results

Characters

White or light yellow powder or crystalline powder. Odorless or slightly odorous. This product is sparingly soluble in water, slightly soluble in ethanol, methanol, acetone or chloroform, sparingly soluble in 0.1mol/L hydrochloric acid solution

White powder. Odorless. sparingly soluble in water, slightly soluble in ethanol, methanol, acetone or chloroform, sparingly soluble in 0.1mol/L hydrochloric acid solution

Melting point

187℃~191℃

(Simultaneous decomposition while melting)

188.7℃~190.6℃

(Simultaneous decomposition while melting)

Identification

(1)should meet the requirements

meet the requirement

(2)should meet the requirements

meet the requirement

(3) The infrared absorption spectrum of this product should be consistent with that of the reference substance (spectrum set 966)

meet the requirement

Test

Related substance

ImpurityⅠ≤0.5%

Single impurity ≤0.1%

Total impurities ≤0.5%

0.16%

0.08%

0.14%

Ethanol

≤0.5%

Not detected

PH

1.5-3.5

2.09

Loss on drying

≤0.5%

0.28%

Residue on ignition

≤0.1%

0.08%

Heavy metals

≤20ppm

meet the requirement

Assay (on drying basis)

≥98.5%

98.8%

Microbe. Test

Total aerobic bacteria: ≤2000cfu/g

<1cfu/g

Yeast & Mold.: ≤200cfu/g

<10cfu/g

Escherichia coli: Not detected

Not detected

Conclusion: The test results comply with CP2020.

 

Functions

Acipimox powder is a substance that is used for a variety of health-related functions. Here are some of the key benefits that this powder provides:

1. Lowering Cholesterol Levels: it has been found to be effective in lowering cholesterol levels in the body. This can be particularly helpful for individuals who have high cholesterol levels and are at risk for heart disease.

2. Reducing Triglyceride Levels: Triglycerides are a type of fat that can build up in the bloodstream and contribute to the development of heart disease. it has been shown to be effective in reducing triglyceride levels, which can help to lower the risk of heart disease.

3. Managing Diabetes: it is also used to help manage diabetes by lowering insulin resistance and improving glucose metabolism in the body. This can lead to better blood sugar control and a reduced risk of complications associated with diabetes.

4. Improving Blood Flow: it has been found to improve blood flow in the body, which can be particularly helpful for individuals with poor circulation or who are at risk for blood clots.

5. Reducing Inflammation: Inflammation is a contributing factor to many chronic diseases, including heart disease, diabetes, and cancer. it has been shown to have anti-inflammatory properties, which can help to reduce the risk of these diseases.

Overall, it is a versatile substance that provides many health benefits. Whether you are looking to lower your cholesterol, manage your diabetes, improve blood flow, or reduce inflammation, this powder may be able to help you achieve your health goals.

 

Application:

Acipimox is a medication that is commonly used to treat lipid metabolism disorders and reduce the risk of cardiovascular disease. It is a type of niacin derivative that works by inhibiting the enzyme triglyceride lipase, which in turn reduces the production of triglycerides in the liver.

One of its main applications is in the treatment of hypertriglyceridemia, which is a condition characterized by high levels of triglycerides in the blood. This condition can contribute to an increased risk of heart disease, stroke, and other cardiovascular complications. it is effective in lowering triglyceride levels in the blood, and studies have shown that it can also improve insulin sensitivity and blood glucose levels in patients with diabetes.

In addition to its role in treating hypertriglyceridemia, it has also been investigated as a potential therapy for other conditions such as metabolic syndrome, non-alcoholic fatty liver disease, and diabetic neuropathy. Limited studies have shown some promising results, but further research is needed to confirm its efficacy in these areas.

it is typically taken orally in the form of capsules or tablets, and the dosage and duration of treatment will depend on the specific condition being treated and other individual factors such as age and overall health. Its common side effects include stomach upset, diarrhea, and flushing, and it may also interact with other medications, so it is important to consult with a healthcare provider before starting treatment.

In summary, it is a medication that is primarily used to treat hypertriglyceridemia and reduce the risk of cardiovascular disease. It may also be helpful in managing other metabolic disorders, but further research is needed to fully understand its potential benefits and limitations. If you are interested in exploring it as a treatment option, it is important to talk to your doctor about whether it may be appropriate for your specific needs and circumstances.

 

Production method

Under cooling and stirring, the 78g Malanic anhydride is dissolved in a solution of 60ml chloroform, and 40ml 30%of the hydrogen peroxide is added. After 2H, add 4.8g of 5-methylpheli Chemicalbook-2-carboxylic acid and keep 2D at 0-5 ° C. Filter to Malay acid. Concentrated to the small volume of the remaining, add acetate, and the filter can get 1.1g of Asimus, and the melting point is 178-180 ° C.

 

Synthetic

Using 2,5-dimethylpyrazine as raw material, KMnO4 was used to oxidize - CH3 at the 2,5-position to two - COOHs, resulting in pyrazine-2,5-dicarboxylic acid. Then, AgNO3 was selectively reduced to the 5-Chemicalbook carboxyl group under H2S gas to generate 5-methylpyrazine-2-carboxylic acid.

product-1-1

Figure 1 shows the synthesis of 5-methylpyrazine-2-carboxylic acid

5-methylpyrazine-2-carboxylic acid is oxidized to Asimus with H2O2 under the catalysis of Na2WO42H2O

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Figure 2 shows the synthesis of Asimus

 

Packing & Shipping

Packing:

1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization:

l Customized logo

l Customized packaging

l Graphic customization

 

Shipping:

By Courier; By Air or By Sea, according to your demands

product-1-1

 

Payment Term

6 payment.webp

Why Choose Xi'an Yihui?

Customer feedback

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

 

Contact Us:

Yihui Pharmaceuticals proudly stands as a professional manufacturer and supplier of Acipimox powder. Our commitment to quality is unwavering, as evidenced by our adherence to international standards and the acquisition of ISO, Kosher, Halal, and GMP certifications. For inquiries or to purchase Acipimox, please contact us immediately at sales@yihiupharm.com

In conclusion, Acipimox powder by Yihui Pharmaceuticals is not just a pharmaceutical product; it represents a breakthrough in cancer treatment with widespread applications across various industries. Our dedication to excellence and adherence to international standards make us the preferred choice for professionals in the pharmaceutical and research sectors.

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