We supply Xylometazoline hydrochloride

We offer Xylometazoline hydrochloride API, a high- quality active pharmaceutical component generally used as a nasal decongestant. it is produced using advanced manufacturing processes that insure its chastity and efficacity. It's suitable for use in the product of a variety of pharmaceutical products. With our commitment to quality, you can trust that our Xylometazoline hydrochloride is safe and effective for use in your phrasings. communicate us moment to learn further about our Xylometazoline hydrochloride and how we can support your requirements.

What's Xylometazoline hydrochloride?

Xylometazoline hcl API is a nasal decongestant medicine that's generally used in the treatment of nasal traffic caused by disinclinations, snap, or other respiratory conditions. This drug works by narrowing the blood vessels in the nasal passages, which helps to reduce inflammation and lump of the nasal apkins.

it is generally administered as a nasal spray or drops, and is available in colorful strengths depending on the inflexibility of the traffic. It's a fast- acting drug that provides relief within twinkles of administration, and can last for over to 12 hours.

As an API( active medicinal component), xylometazoline hcl is used as the primary active component in colorful phrasings of nasal decongestant products. It's a safe and effective drug that has been considerably tested for its safety and efficacity in multitudinous clinical trials.

Overall, it is extensively used in both untoward and tradition nasal decongestant products, and is a trusted and effective treatment for nasal traffic. It provides presto and long- lasting relief for those suffering from nasal traffic due to disinclinations, snap, or other respiratory conditions.

Basic Information

Product Name: Xylometazoline Hydrochloride

CAS: 1218-35-5

MF:C16H25ClN2

MW:280.84

EINECS:214-936-4

MDL No.:MFCD00238707

Structural formula:

Origin: China

Delivery Time: in stock

Technical Specification

Package: 1kg;10kg; 25kg or according to your demands

Storage: Preserve in tight,light-resistant containers in cool place

Shelf Life:Powder: 2 years

Application

Xylometazoline hydrochloride API is a potent nasal decongestant that's generally used to relieve symptoms associated with nasal traffic arising from disinclinations, influenza, or common cold wave. The medicine works by constricting the blood vessels in the nasal passages, thereby reducing swelling and allowing for easier breathing.

it is generally used in a wide range of pharmaceutical phrasings, including nasal sprays and drops, which are available over the counter and can be fluently tone- administered by cases. The medicine has been shown to give rapid-fire and effective relief from nasal traffic symptoms, with goods lasting for several hours.

Away from its remedial operations, it is also used in exploration settings, particularly in studies involving beast models of respiratory conditions. The medicine is extensively honored for its safety profile, as well as its efficacity in treating a range of nasal traffic conditions.

Overall, it is an essential element of numerous pharmaceutical phrasings and has a significant positive impact on the quality of life of cases suffering from nasal traffic symptoms. Its versatility and broad operations make it an essential medicine in numerous healthcare surrounds.

Biological activity 

Xylometazoline hcl API is a largely active pharmaceutical component used in a variety of medicinal products. This emulsion is classified as a potent vasoconstrictor, which means it has the capability to constrict blood vessels in the body. This makes it largely effective in reducing nasal and sinus traffic caused by disinclinations, snap, and other respiratory affections.

it is generally set up in nasal sprays and drops due to their fast- acting nature. The emulsion works by constricting blood vessels in the nasal passages and reducing the swelling that causes traffic. This provides rapid-fire relief from nasal traffic and allows for easier breathing.

also, it has proven efficacity in easing symptoms associated with sinusitis, otitis media, and other upper respiratory tract infections. Its capability to reduce inflammation and mucosal edema makes it a popular component in these products.

The natural exertion of xylometazoline hydrochloridealso extends to its use in ophthalmic operations. Its vasoconstrictive parcels make it ideal for treating eye greenishness caused by disinclinations or vexation. Its capability to reduce blood inflow to the eyes and reduce swelling within twinkles of administration makes it a largely precious component in eye drops and ointments.

In conclusion, it is a largely active medicine used in a wide range of medicinal products. Its capability to reduce inflammation, mucosal edema, and blood vessel dilation makes it a precious remedial agent for managing nasal and eye traffic symptoms. Its proven efficacity and fast onset of action make it a popular component in untoward and tradition specifics for upper respiratory tract infections and inflammation.

Synthesis route

1,3-dimethyl-5-tert-butylbenzene is used as the starting material. In the presence of a catalyst, it reacts with a chloromethylation reagent to gain 2,6- dimethyl-4-tert-butyl-1-chloromethylbenzene; cyanation response is carried out with sodium cyanide to gain 2,6- dimethyl-4-tert-butyl-1-phenylacetonitrile, which is also cyclized with ethylenediamine p- toluenesulfonate to gain xylometazoline p- toluenesulfonate( 11); xylometazoline is freed with a base and also interspersed with hydrogen chloride to gain xylometazoline hydrochloride. The failings of this process route are tert- butyl- m- xylene has a high request price; chloromethyl ether is largely poisonous, has a low boiling point and a high request price; largely poisonous detergents similar as carbon disulfide have a low boiling point and poor response operability. Another synthetic route is 2,6- dimethyl-4-tert-butylaniline hydrochloride is used as the starting material to reply with sodium nitrite, bobby

sulfate, and polyformaldehyde to induce 2,6- dimethyl-4-tert-butylbenzaldehyde, which is reduced to alcohol and also chloromethylated, hydrogenated, aminoesterified, cyclized, and interspersed to induce xylometazoline hydrochloride. The synthetic route has long way and complexpost-processing. After analysis and comparison, the diazotization response in this synthetic system generally has a low yield. The use of thionyl chloride has great environmental pollution. It's delicate to gauge up product, and the performing product has numerous contaminations and low product chastity. In short, this synthetic system has a long process route, clumsypost-processing, low finished product yield, high product cost, and is delicate to achieve large- scale artificial product.

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Yihui takes pride in being a trusted Xylometazoline hydrochloride API manufacturer and supplier. To acquire this groundbreaking product or discuss your specific requirements, contact us immediately at sales@yihuipharm.com. Rest assured, with Yihui, you're accessing a product of unparalleled quality, backed by certifications that underscore our commitment to excellence in the global market.