Polymyxin B Sulphate

CAS:1405-20-5
Package: 100g/bag;500g/bag;1kg/bag
Origin: China
Supply Ability: 1000kg per month
Sample Available: Yes
Shelf Life: Two years
Payment: T/T, LC or DA
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Third Party Test: available
Plant Audition: available
Can't sell to individuals
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Product Introduction

What is Polymyxin B Sulphate?

Polymyxin B Sulphate is an antibiotic belonging to the class of polypeptides. It's insulated from Polymyxa strains of Gram-negative bacteria and has strong bactericidal goods against numerous Gram-negative bacteria. Its main factors are a variety of polypeptide antibiotics, including polypeptide B1, B2, B3, and other polypeptide analogous composites, its molecular formula is C56H100N16O17S, its molecular weight is about 1200- 1400 Da, its CAS number is 1405-20-5. The structural specificity of these polypeptide antibiotics is that they contain veritably hydrophobic long-chain adipose acid bases, and their main medium of action is to destroy the bacterial cell wall, leading to bacterial death.it is extensively used to treat contagious symptoms caused by Gram-negative bacteria, similar to pneumonia, sepsis, urinary tract infections, ans so on.

originally, It was insulated from soil by American scientists TrumanW. Brody and StuartL. Brown in the early 1940s. They set up that this emulsion had strong bactericidal goods against Gram-negative bacteria and named it" Polymyxin B" in 1949. This discovery has had a significant impact on the field of bacterial infection treatment.

Basic Information

Product name

Polymyxin B Sulphate

Chemical name

POLYMYXIN B;POLYMYXIN-B 2,5-SULFATE;POLYMYXIN B SULFATE;POLYMYXIN B SULFATE, BACILLUS POLYMYXA;POLYMYXIN B SULFATE SALT;POLYMYXIN B (PMB);POLYMIXIN B SULFATE

CAS

137234-62-9

MF

C16H14F3N5O

MW

349.31

EINECS

629-701-5

MDL No.

MFCD00905717

Purity

99%

Stability

stable when stored under appropriate conditions.

solubility

DMSO >20mg/mL

Application

used for research.

Packing

As per your request

Storage

Room temp.

Structural formula

      137234-62-9.webp         

Quality standard

Test items

Specification

Test results

Appearance

White to buff-colored powder,odorless or has a fain odor

White hygroscopic powder

Identification

HPLC

Conforms


Color reaction with cupric sulfate solution

Conforms


Sulfate reaction

Conforms

PH

5.0-7.5(20mg/ml)

6.52

Loss on drying

≤7.0%

1.87%

Content of phenylalanine

9%-12%(dried basis)

11.1%

Microbiological examination

TAMC: ≤10cfu/g

Conforms


TYMC: ≤10cfu/g

Conforms


Staphylococcus aureus: undetected

Conforms

Assay

≥ 6000u/mg (Anhydrous)

7832u/mg

Conclusion

Conforms to USP

Stability

Polymyxin B Sulphate is stable in acidic solutions and can maintain its potency within the pH range of 3-8, while it is unstable in alkaline solutions. In neutral solutions, a week at room temperature does not affect its titer. However, it easily absorbs moisture under humid conditions, so it should be stored in a dry and ventilated place while avoiding prolonged exposure to humid environments. When using it, attention should be paid to storage conditions and solution pH to ensure its stability and efficacy.

Solubility

Its solubility depends on the solvent and solution temperature used. Its solubility is very low In water, about 0.5 mg/mL.

Furthermore, its solubility can also be increased by adjusting the pH value. Therefore, suitable solvents need to be chosen and different conditions tried to improve its solubility.

Storage

Its storehouse conditions should be dry, cool, voiced, light-shielded, and sealed. Polymyxin B Sulphate API should be stored in a sealed vessel in a cool and breezy place down from fire sources and ignitable substances to avoid exposure to sticky surroundings, which can affect its stability and efficacity. It also needs to be stored independently from food, potables, drugs, and other chemicals to avoid cross-contamination.

Packing & Shipping

Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization: Customized logo; Customized packaging; Graphic customization

Shipping:

Item

Quantity

ETA time

Shipping Method

By Courier

≤50kg

7-15days

Fedex, DHL,UPS,TNT,EMS ect.

Fast and convenient

By Air

50kg~200kg

3-5days

Fast and cheap

By Sea

Large quantity

20-35days

Cheapest way

Payment Term

payment.webp

Why Choose Xi'an Yihui?

Customer feedback

 Customer Comments.webp

Xi'an Yihui certificates

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Xi'an Yihui Factory & Warehouse

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Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition, and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

In conclusion

As a 99 Polymyxin B Sulphate plant, we will give our guests high-quality Polymyxin B Sulphate. We'll establish a complete service system, give technical specialized support and after-deal services, and make every trouble to ameliorate client satisfaction.

Our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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