Oxaliplatin Powder
Appearance: White or almost white crystalline powder
standard: USP/EP
Brand: YIHUI
Packing: 1kg;100G;10G
Supply Ability: 50Kg per month
Shelf Life: Two years
Application: antitumor ; lab research
Payment: T/T, LC or DA
Sample: available
Delivery Time: Ready Stock in Local Warehouse,1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL,FedEx,TNT,EMS,By Sea,By Air
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Can't sell to individuals
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Product Introduction
What is Oxaliplatin Powder?
Oxaliplatin belongs to platinum derivations and is clinically used to treat cases with colorectal cancer metastasis who have failed fluorouracil treatment. It can be used alone or in combination with fluorouracil. It's the third generation of new platinum groundedanti-tumor composites after cisplatin and carboplatin, and is also the only platinum grounded medicine with significant exertion against colorectal cancer to date. The principle of action is to produce alkylated conjugates that act on DNA, forming intra- and inter chaincross-linking to inhibit DNA conflation and replication. At the same time, it also has an inhibitory effect on the proliferation of ovarian cancer and carcinoma cell lines in Chemicalbook. In August 2002, the US Food and Drug Administration( FDA) approved Sanofi Santa Trabao'santi-cancer medicine, oxaliplatin( Eloxatin), for alternate- line treatment of metastatic colon cancer. In January 2004, the US Food and Drug Administration( FDA) officially approved the first- line treatment of advanced colorectal cancer with oxaliplatin( losartan) for injection in combination with 5- fluorouracil( 5FU) and folic acid( LV)( FOLFOX authority).
Basic Information
Product Name: oxaliplatin
CAS: 61825-94-3
MF:C8H12N2O4Pt
MW:395.28
EINECS:621-248-1
MDL No.:MFCD00866327
Purity: 99%
Package: 10g;100g;1kg
Used: pharma grade & Lab research
Stability: Stable
Structural formula:
Specification Parameter
Items | Specifications | Results |
Appearance | White or almost white, crystalline powder | White, crystalline powder |
Identification | ||
A: IR | The positions and the relative sizes of the bands in the spectrum of the sample are concordant with those in the spectrum of the reference standard. | Conforms |
B: Specific optical rotation | It complies with the test for specific optical rotation. | Conforms |
Tests | ||
Appearance of solution | Clear and colourless | Conforms |
Acidity | Not more than 0.60ml of 0.01M NaOH is required to change the color of the indicator to pink | 0.36ml |
Specific optical rotation | +74.5 to +78.0 | +76.4 |
Impurity D | Not more than 0.15% | 0.072% |
Related substances: | ||
Impurity A | Not more than 0.15% | 0.022% |
Impurity B | Not more than 0.15% | 0.035% |
Impurity C | Not more than 0.15% | 0.0084% |
Unspecified impurities | Not more than 0.10% | Undetected |
Sum of unspecified impurities | Not more than 0.15% | Undetected |
Sum of impurities other than D | Not more than 0.30% | 0.065% |
Silver | Max 5ppm | 1.0ppm |
Loss on drying | Max 0.5% | 0.06% |
Bacterial endotoxins | Less than 1.0IU/mg | 1.0IU/mg |
Assay | 98.0%~102.0% | 100.2% |
Microbial limits | ||
Total aerobic bacteria count | Not more than 2000cfu/g | 100cfu/g |
Total combined yeast and molds count | Not more than 200cfu/g | 100cfu/g |
Search phtaogens | ||
E. coli | Should be absent in 1g of Oxaliplation | Undetected |
Salmonella spp | Should be absent in 1g of Oxaliplation | Undetected |
P. aeruginosa | Should be absent in 1g of Oxaliplation | Undetected |
S. aureus | Should be absent in 1g of Oxaliplation | Undetected |
Conclusion: the batch conforms to the specification of Oxaliplatin in current PH. Eur. |
Chemical Composition
The Oxaliplatin Powder's chemical composition is meticulously formulated to ensure optimal performance. The primary constituents include platinum, carbon, hydrogen, nitrogen, and oxygen. This unique combination forms the foundation for Oxaliplatin's efficacy in various applications.
Effects and Functions
Oxaliplatin Powder is a cornerstone in chemotherapy, especially in the treatment of colorectal cancer. Its essential capability is to hinder DNA synthesis in disease cells, which upsets their development and eventually prompts cell passing through apoptosis.
By interfering with DNA replication, Oxaliplatin effectively targets rapidly dividing cancer cells, helping to slow down tumor growth and reduce the spread of cancer. Its mode of action involves forming DNA adducts, which are abnormal structures that prevent proper DNA replication and transcription. This disruption in the cancer cell's DNA repair mechanisms leads to its demise.
Oxaliplatin is for the most part used to treat colorectal malignant growth, however it might likewise be powerful against different kinds of disease.Research is being led to investigate its viability in ovarian disease, pancreatic malignant growth, and other strong cancers.. This expands its utility in the medical field and offers hope for patients with various types of cancer.
Synthesis Process
Our advanced synthesis process involves a series of precise steps. Oxaliplatin is blended through the response of diaminocyclohexane platinum (II) with dichloro(ethylenediamine) platinum (II). This strategy guarantees a predictable and great item, fulfilling the severe guidelines set by Yihui.
Quality Standards
Yihui takes pride in adhering to international quality standards to guarantee the excellence of CAS 61825-94-3. Our obligation to giving products of the greatest quality is shown by the way that our production facilities are ISO, Kosher, Halal, and GMP certified.
Application Fields in Various Industries
Oxaliplatin has potential applications outside of healthcare and can be used in different industries such as research and development. It serves as a valuable tool in studying platinum-based drugs due to its platinum-containing compound properties. Researchers can use Oxaliplatin as a model to understand the characteristics and potential applications of other platinum-based drugs.
Additionally, Oxaliplatin can also play a crucial role in the synthesis of novel compounds with potential applications across various sectors. Its particular properties make it an optimal contender for growing new materials or components for electronics, catalysis, and other modern applications.
For instance, researchers have studied the potential of using Oxaliplatin in the development of platinum(II) complexes with photocatalytic activity for water splitting. the versatility of the product highlights its significance in advancing innovation and improving products and processes in different sectors beyond healthcare. Its unique properties and mechanisms of action make it a valuable tool in research and development and chemical manufacturing, providing opportunities for developing novel compounds with potential applications in diverse industries.
Contact Us
Yihui stands as a leading Oxaliplatin Powder manufacturer and supplier committed to meeting the demands of professional buyers and global dealers. Our dedication to product quality is evident through adherence to international standards and certifications such as ISO, Kosher, Halal. For inquiries or purchases, contact us at sales@yihuipharm.com.
All in all, Yihui's product is a demonstration of our obligation to greatness and development, making it a favored decision for those looking for first-class quality in the drug and related businesses.
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