We supply Miconazole Nitrate API

We're a leading supplier of Miconazole Nitrate API. It's an antifungal drug used to treat a variety of fungal infections. Our product comes in high chastity form and is manufactured under strict quality control norms.

We understand the significance of product quality and strive to deliver the stylish quality products to our guests. Our product is extensively used by pharmaceutical companies and is trusted for its harmonious quality and effectiveness.

still, we're the right choice for you, If you're looking for a dependable supplier of Miconazole Nitrate powder . We offer competitive prices and prompt delivery to meet your requirements. communicate us moment to place your order.

What's Miconazole Nitrate API

Miconazole nitrate is an antifungal agent that's generally used in the treatment of colorful fungal infections. It's a white crystalline greasepaint and is fluently answerable in water and alcohol. it is retailed under colorful brand names and is available in colorful forms, including creams, poultices, maquillages, and gels.

Pure Miconazole nitrate powder is primarily used for the treatment of skin infections, similar as athlete's bottom, jock itch, ringworm, and other fungal infections. It works by inhibiting the growth of fungi and precluding them from reproducing. This helps to exclude the infection and reduce the symptoms associated with it.

In addition to treating skin infections, it is also used in the treatment of vaginal incentive infections. It's available in the form of vaginal creams and suppositories, and works by inhibiting the growth of the incentive that causes the infection.

It is considered to be a safe and effective treatment for fungal infections, with fairly many side goods. still, some people may witness mild skin vexation or antipathetic responses when using products containing miconazole nitrate. It's important to follow the instructions on the product marker and consult a healthcare professional if you witness any adverse goods.

As an active pharmaceutical component( API), it is extensively used in the pharmaceutical assiduity for the product of antifungal specifics. It's also used in the cosmetics assiduity to help the growth of fungi and bacteria in particular care products.

Overall, it is a precious antifungal agent that has been proven effective in the treatment of colorful fungal infections. Its wide vacuity and fairly low threat of side goods make it a popular choice for both healthcare professionals and consumers.

Basic Information

Product name: Miconazole nitrate

CAS: 22832-87-7

MF:C18H15Cl4N3O4

MW:479.14

EINECS:245-256-6

MDL No.:MFCD00058161

Structural formula:

Purity: 99%+

Origin: China

Application: Antifungal

Delivery Time: stock

Technical Specification:

Package: 1kg; 25kg

Storage conditions: keep tightly closed, store in a cool dry place.

What is the application of miconazole nitrate?

For broad-spectrum antifungal drugs to treat deep fungal infections

Antifungal drugs

What is The mechanism of action of miconazole nitrate?

(1) Interfering with the activity of cytochrome P450, inhibiting the biosynthesis of ergosterol in fungal cell membranes, damaging fungal cell membranes and altering their permeability, leading to the leakage of important intracellular substances.

(2) Inhibition of fungal biosynthesis of triacylglycerol and phospholipids.

(3) Inhibiting the activity of oxidase and peroxidase leads to excessive accumulation of hydrogen peroxide in cells, causing fungal substructure degeneration and cell necrosis.

(4) Candida albicans can inhibit its transformation from spores to invasive hyphae.

Antifungal drugs

Miconazole nitrate API is an antifungal drug commonly used in the treatment of psoriasis, known as daconazole. pure Miconazole nitrate powder  inhibits the biosynthesis of ergosterol, a fungal cell membrane component, destroys the cell membrane structure, increases the permeability of the cell membrane, leads to the leakage of intracellular components, inhibits glucose utilization, prevents nutrient uptake, and ultimately leads to fungal cell death. It is suitable for treating tinea corporis, tinea cruris, tinea manus, tinea pedis, tinea versicolor, as well as fungal paronychia and vaginal infections and secondary infections caused by yeast (such as Candida) and Gram positive bacteria. It is also effective for treating external otitis and bacterial skin infections.

Common adverse reactions and side effects of miconazole nitrate include occasional allergies, blisters, burning sensation, congestion, itching, or other skin irritation symptoms. Very rare vascular neuroedema, urticaria, eczema, contact dermatitis, erythema, pelvic pain (spasms), vaginal irritation, vaginal discharge, and discomfort at the administration site.

Antibacterial spectrum

Miconazole nitrate powder has good antibacterial effects on various deep fungi (such as Candida albicans, Aspergillus niger, Cryptococcus neoformans, Bacillus subtilis, Saccharomyces cerevisiae), certain epidermal fungi such as Chemicalbook and yeast. It also has antibacterial effects on Gram positive cocci (such as Staphylococcus, Streptococcus) and bacteria (such as Bacillus anthracis).

Drug interactions

(1) When used in combination with anticoagulants such as coumarins or derivatives of indomethacin, the effect of such drugs can be enhanced, leading to prolonged prothrombin time. Patients should be closely monitored, prothrombin time should be monitored, and the dosage of anticoagulants should be adjusted.

(2) it can increase the blood concentration of cyclosporine and may increase the risk of nephrotoxicity. When the two drugs are used together, the blood concentration of cyclosporine should be monitored.

(3) Rifampicin can enhance the metabolism of this product, increase liver toxicity, and when used in combination, it can reduce the blood drug concentration of this product, leading to treatment failure. When used in combination with isoniazid, the blood drug concentration of this product can also be reduced, so caution should be exercised when using the above drugs.

(4) The combination of phenytoin sodium and it can cause changes in the metabolism of both drugs and delay the peak time of this product. When using the two drugs together, their reactions should be closely observed.

(5) When used in combination with hypoglycemic drugs, it can lead to severe hypoglycemia due to the inhibition of the latter's metabolism.

(6) Combination with cisapride is contraindicated as it inhibits cytochrome P450 metabolic channels and can lead to arrhythmia. If it is used in combination with aspirin or terfenadine, there is also a risk of arrhythmia, so it should also be avoided.

In conclusion

In summary, as a professional Miconazole nitrate APImanufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make it stand out in the market competition and win more customer trust and support. if you need Miconazole nitrate powder, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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