Diltiazem hydrochloride powder

CAS No: 201530-41-8
Appearance: white or off-white powder
Standard: in-house, 99%
Supply Ability: 500kg per month
Shelf Life: Two years
Application: Anti-Anemia
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Can't sell to individuals
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Product Introduction

We supply Diltiazem hydrochloride

We offer Diltiazem hydrochloride API, a medication used to treat high blood pressure and angina. This medication works by relaxing the blood vessels, allowing for improved blood flow and reduced strain on the heart. Our Diltiazem hydrochloride powder is of high quality and purity, and we guarantee its effectiveness and safety. It is available in different forms such as tablets and capsules. Contact us to learn more about our Diltiazem hcl and how it can benefit you or your patients.

 

What is Diltiazem hydrochloride powder?

Diltiazem hydrochloride powder is a white, odorless, crystalline powder that is commonly used in the pharmaceutical industry. It is a calcium channel blocker that works by inhibiting the flow of calcium ions into heart muscles and blood vessels, thereby relaxing and dilating them. This API is commonly used to treat hypertension, angina, and arrhythmia.

it is approved by the US FDA and is considered safe and effective for treating cardiovascular disorders. It is a potent vasodilator, meaning it can significantly improve blood flow and reduce blood pressure in patients suffering from hypertension. It can also help to reduce the frequency and severity of episodes of angina.

This API has a very low toxicity profile and is generally well-tolerated by patients. However, some side effects may occur, including headache, dizziness, flushing, fatigue, bradycardia, and constipation. Patients with impaired liver and kidney function may require a lower dosage of this API, and caution should be taken when administering it in elderly patients.

In summary, Diltiazem hcl powder is a potent calcium channel blocker that is widely used in the treatment of cardiovascular disorders. It is considered safe and effective, and its availability in various forms and routes of administration make it a flexible treatment option for patients.

 

Basic Information

Product Name: Diltiazem hydrochloride

CAS NO: 33286-22-5

MF:C22H27ClN2O4S

MW:450.98

EINECS:251-443-3

MDL No.:MFCD00069252

Purity: 99%+

MOQ: 1kg

Origin: China

Application: Pharmaceutical Ingredient

Delivery Time: 3-7days

Structural formula:

product-1-1

Melting point: 212-214 ° C

Specific rotation: D24+98.3 ± 1.4 ° (c=1.002 inmetanol)

Density: 1.30g/Chemicalbookcm3

Refractive index: 118 ° (C=1, H2O)

Flash point: 2 ℃

Storage conditions: 2-8 ° C

Solubility: Easily soluble in water, methanol, and dichloromethane, slightly soluble in anhydrous ethanol.

 

Technical Specification:

Items

Specification

Test Results

Characteristics

A white Crystalline powder

Conforms

Identification (by HPLC)

Corresponds to the requirement of the reference standard

Conforms

Specific optical rotation

+1100-+1160

+114.90

Assay (on dried)

98.5%-101.5%

99.56%

Melting range

210℃-215℃

213.0℃-213.5℃

Loss on drying

≤0.5%

0.29%

Residue on ignition

≤0.1%

0.06%

PH

4.3-5.3

5.0

Heavy metals

≤20ppm

Conforms

Related substances:

Single impurity

Total impurity

 

≤0.5%

≤1.0%

 

0.35%

0.57%

Analytical conclusion

Conforming to USP

Package: 1kg/bag; 25kg/drum

Storage conditions: Keep in dark place, Inert atmosphere,2-8°C

 

Safety Information

Dangerous goods labeling: Xn, Xi, F

Hazard category code: 22-40-36/37/38-36-20/21/22-11

Safety instructions: 36-45-36/37-26-26

Dangerous goods transportation number: 3249

WGK Germany: 3

RTECS number: DL0310000

F: 8-10

Hazard level: 6.1 (b)

Packaging category: III

Customs code: 29349990

Toxicity: LD50 in male, female mice, male, female rats (mg/kg): 61, 58, 38, 39 i.v.; 260, 280, 520, 550 s.c.; 740, 640, 560, 610 orally (Nagao, 1972)

 

What is the application of Diltiazem hydrochloride powder

Diltiazem hydrochloride powder is calcium channel blockers, used for supraventricular arrhythmias, angina, elderly hypertension, etc. This product is a coronary vasodilator and is effective in treating angina pectoris. Used for the treatment of angina caused by exercise induced angina and old induced myocardial infarction. This product has an oral LD50 of 640 mg/kg for female mice and 560 mg/kg for male rats.

Diltiazem hcl powder is Calcium channel blockers, used to treat supraventricular arrhythmias, angina pectoris, elderly hypertension, etc

 

Preparation method

2- (4-methoxyphenyl) -3-hydroxy-1,5-benzothiaza-4 (5H) - one was synthesized by condensation of 2-aminothiophenol with ethyl p-methoxyphenyl epoxypropionate. Thiazone is synthesized by acylation, condensation with dimethylaminochloroethane, and salt formation.

Our Advantage

Rich experience: we have 13 Years of professional experience;

Customers all over the world: sell to more than 100 countries;

Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.

Price advance: low MOQ with competitive price;

Quality certification: ISO; Halal; Kosher certified

After-sales service: Professional team 7*24 hours customer service.

 

In conclusion

In summary, Xi'an Yihui company as a professional Diltiazem hydrochloride powder manufacturer has strong technical strength and advanced production equipment and is committed to providing customers with high-quality, efficient and reliable drug raw materials. if you need it, pls feel free to contact us any time. we will reply you asap.

our contact information:

E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
WeChat or WhatsApp: 0086-17792415937

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