Clopidogrel bisulfate API
Appearance: White to off-white powder
Standard: USP
Packing: 25kg/drum
Shelf Life: Two years
Application: Antithrombotic
Payment: T/T, LC or DA
Delivery Time: Ready Stock in Local Warehouse, 1-3 days
Prompt and Secure Shipment
Origin: China
Shipping: DHL, FedEx, TNT, EMS, By Sea, By Air
Certifications: ISO9001, ISO22000, HACCP, HALAL, KOSHER
Can't sell to individuals
- Fast Delievery
- Quality Assurance
- 24/7 Customer Service
Product Introduction
Clopidogrel Bisulfate:A Leading result for Cardiovascular Health
At Yihui company, we take pride in furnishing high- quality Clopidogrel bisulfate API to meet the requirements of pharmaceutical manufacturers, healthcare providers, and medical experimenters worldwide. it is manufactured under strict quality control norms to insure harmonious energy, safety, and effectiveness. With cardiovascular conditions getting a significant concern across the globe, the demand for dependable and high- quality active pharmaceutical constituents( APIs) has noway been lesser. it plays a critical part in reducing thrombotic events and perfecting patient issues in the application of heart complaint and other affiliated conditions.
We Supply Clopidogrel Bisulfate
As a trusted supplier in the pharmaceutical assiduity, we're committed to furnishing top- notch Clopidogrel bisulfate to pharmaceutical companies, contract manufacturers, and other healthcare stakeholders. it is developed using slice- edge technology and sourced from the most estimable manufacturers to insure the loftiest situations of chastity and efficacity. We understand the critical nature of cardiovascular treatment, and we aim to support the development of effective curatives by furnishing Clopidogrel bisulfate in its stylish possible form.
Whether you're working on the development of tablets, capsules, or other medicine phrasings, it serves as the foundation for delivering dependable and effective cardiovascular specifics. Our product is designed to help pharmaceutical companies meet both nonsupervisory norms and patient requirements, icing that the final products are both safe and effective in treating a variety of cardiovascular conditions.
What's Clopidogrel Bisulfate?
Clopidogrel bisulfate powder is the active pharmaceutical component used in the product of Clopidogrel- grounded specifics. Clopidogrel itself is an antiplatelet agent that works by precluding the conformation of blood clots, a crucial threat factor in numerous cardiovascular conditions. It's generally used in the forestallment and treatment of heart attacks, strokes, and other thrombotic events caused by blood clot conformation.
it is the swab form of Clopidogrel, designed to ameliorate the stability and solubility of the active component. The bisulfate swab form ensures that Clopidogrel remains effective when administered in colorful lozenge forms, similar as oral tablets and capsules. It's primarily used as an oral drug, where it's metabolized in the liver and converted into its active form. This active form also inhibits platelet aggregation, significantly reducing the threat of clot conformation.
it is essential in the creation of remedial phrasings that aim to reduce the threat of blood clot conformation, making it a precious element in the fight against cardiovascular conditions.
Basic Information
Product Name: Clopidogrel Bisulfate
CAS: 120202-66-6
MF:C16H16ClNO2S.H2O4S
MW:419.9
EINECS:1806241-263-5
MDL No.:MFCD00876395
Structural formula:
Appearance: White to off-white powder
Standard: USP
Packing: 25kg/drum
Shelf Life: Two years
Application: Antithrombotic
Origin: China
Delivery Time: in stock
Technical Specification
Items |
Specifications |
Results |
Appearance |
White to off-white powder |
off-white powder |
Solubility |
Freely soluble in water and in methanol; practically insoluble in ether. |
Conform |
Identification |
|
|
Infrared absorption |
Positive |
Conform |
Retention time(HPLC) |
Positive |
Conform |
Sulfate |
Positive |
Conform |
Loss on drying |
≤0.5% |
0.2% |
Residue on ignition |
≤0.1% |
0.1% |
Related compounds |
|
|
Related compound A |
≤0.2% |
N.D. |
First enantiomer of related compound B |
≤0.3% |
0.08% |
Related compound C |
≤1.0% |
0.04% |
Any other impurity |
≤0.1% |
0.08% |
Total impurity |
≤1.5% |
0.21% |
Residue solvents |
|
|
Acetone |
≤5000ppm |
344ppm |
Ethyl acetate |
≤5000ppm |
663ppm |
Methylene dichloride |
≤600ppm |
N.D. |
Assay(on the dried basis) |
97.0%~101.5% |
100.0% |
Conclusion: comply with USP. |
Package: 25kg
Storage: Seal and store in a cool, dry place. Ensure that the workspace has good ventilation facilities. Keep away from sources of fire and store away from oxidants.
Shelf Life: 24 months
The Characteristics of Clopidogrel Bisulfate
Clopidogrel bisulfate API possesses a number of crucial characteristics that make it a precious and effective agent for cardiovascular health
Mechanism of Action:The primary action of Clopidogrel bisulfate is its capability to inhibit platelet aggregation, which helps help blood clot conformation. It works by irreversibly binding to the P2Y12 receptor on platelets, precluding adenosine diphosphate( ADP) from cranking the platelets. By blocking this pathway, it ensures that platelets do n't clump together, significantly reducing the liability of clots forming in blood vessels.
Formulation Stability: The bisulfate form of Clopidogrel enhances its solubility and stability compared to other swab forms, icing that the active component is duly absorbed when consumed. This is pivotal for the effectiveness of the drug, as it allows for predictable bioavailability and remedial issues.
Physical Properties: it appears as a white to out-white crystalline powder. It's odorless, slightly bitter in taste, and largely answerable in water. These parcels make it an ideal seeker for addition in oral lozenge forms, as it ensures ease of administration and effective immersion in the gastrointestinal tract.
Safety and Tolerability: As with any pharmaceutical product, safety is a top precedence. it has been considerably studied and is generally well- permitted in cases. still, it's important to note that, as with all specifics, there may be lateral effects, including an increased threat of bleeding. Careful medical supervision is essential when using it in high- threat populations.
Bioavailability: After oral administration, it is metabolized in the liver into its active form. The bioavailability of Clopidogrel after oral administration is around 50, and it reaches peak tube attention roughly 2 hours after ingestion. The delayed release of the active form allows for dragged remedial effects, icing nonstop inhibition of platelet aggregation.
Effects
Clopidogrel bisulfate powder plays a pivotal part in precluding thrombotic events by inhibiting platelet aggregation. The effects of Clopidogrel bisulfate are vital for cases at threat of heart attacks, strokes, and other thrombotic complications. Below are some of the crucial effects:
Reduction of Thrombotic Events: it has been proven in clinical studies to significantly reduce the threat of heart attacks, ischemic strokes, and other cardiovascular events in high- threat cases. Its antiplatelet effects help to help the conformation of dangerous blood clots, which can block blood inflow to vital organs and apkins.
Prevention of Stent Thrombosis: For cases witnessing procedures similar as coronary roadway stent placement, it is generally specified to help the conformation of clots within the stent, a condition known as stent thrombosis. This is a serious complication that can affect in the failure of the stent and the onset of farther cardiovascular complications.
Post-Heart Attack and Post-Stroke Care: After a heart attack or stroke, cases are at increased threat of passing posterior thrombotic events. it is constantly used in these situations to help farther damage to the heart and brain by reducing the liability of clot conformation.
Dual Antiplatelet Therapy (DAPT): Clopidogrel bisulfate is frequently used in combination with aspirin as part of binary antiplatelet remedy( DAPT) for cases who have endured acute coronary pattern or experienced procedures like percutaneous coronary intervention( PCI). This combination provides a more important remedial effect in reducing the threat of blood clots.
Improvement in Cardiovascular Outcomes: By precluding clot conformation, it helps ameliorate overall cardiovascular issues. It supports the application of conditions like supplemental roadway complaint( PAD) and reduces the threat of complications that can arise from poor blood rotation.
Applications
Clopidogrel bisulfate has a wide range of applications in the forestallment and treatment of cardiovascular conditions. Some of the primary remedial uses of Clopidogrel bisulfate include
Acute Coronary Syndrome (ACS): it is generally specified to cases with ACS, which includes unstable angina,non-ST-segment elevation myocardial infarction( NSTEMI), and ST- member elevation myocardial infarction( STEMI). By reducing platelet aggregation, it reduces the threat of farther clotting and complications.
Prevention of Stroke and Heart Attack: it is constantly used to help recreating heart attacks and strokes, particularly in cases with a history of these events or underpinning conditions similar as atherosclerosis.
Peripheral Artery Disease (PAD): For cases with PAD, it helps help blood clots, ameliorate blood rotation, and reduce the threat of complications similar as branch amputation.
Post-Surgical Care: it is frequently used after surgeries like coronary roadway bypass grafting( CABG) or stent placement to reduce the threat of clot conformation at the surgical point and insure smooth recovery.
Dual Antiplatelet Therapy (DAPT): As mentioned before, it is a crucial element of DAPT, which is specified to cases at high threat of clot conformation, especially after PCI or stent placement.
Other Cardiovascular Conditions: it is also useful in the treatment of conditions like atrial fibrillation and deep tone thrombosis( DVT), where there's an increased threat of clotting.
Conclusion
Clopidogrel bisulfate is a pivotal element in the treatment and forestallment of cardiovascular conditions. By effectively inhibiting platelet aggregation and reducing the threat of thrombotic events, it plays a vital part in perfecting patient issues, especially in high- threat individualities. At Yihui company, we're proud to supply top- quality Clopidogrel bisulfate, enabling pharmaceutical manufacturers to produce safe and effective cardiovascular specifics. communicate us moment to learn further about how our Clopidogrel bisulfate can help enhance your medicinal phrasings and support better health issues for cases.
Packing & Shipping
|
Packing: 1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request. Customization: l Customized logo l Customized packaging l Graphic customization Shipping: By Courier; By Air or By Sea, according to your demands |
Payment Term
Why Choose Xi'an Yihui?
Customer feedback
Xi'an Yihui certificates
Welcome to Xi'an Yihui Factory
Contact Yihui:
Yihui Pharmaceuticals, as a professional Clopidogrel bisulfate API manufacturer and supplier, is committed to delivering exceptional quality. Our adherence to international standards and prestigious certifications, including ISO, Kosher, and Halal, underscores our dedication to product excellence. For inquiries or to purchase Clopidogrel bisulfate powder, please contact us immediately at sales@yihuipharm.com. Choose Yihui Pharmaceuticals for unparalleled quality and reliability in every batch of Clopidogrel bisulfate.
Send Message
If you have any enquiry about quotation or cooperation, please feel free to email us at E-mailor use the following enquiry form. Our sales representative will contact you within 24 hours.Thank you for your interest in our products.