We supply Finerenone API

Our company is proud to offer the Finerenone API, a high- quality medicinal active component used in the treatment of colorful medical conditions. Finerenone is a potent and picky nonsteroidal mineralocorticoid receptor antagonist, able of reducing inflammation and fibrosis in colorful organs. With its outstanding remedial eventuality and proven safety, it is an ideal choice for medicine development and medical exploration purposes. Our product is manufactured to the loftiest norms using state- of- the- art technology, icing harmonious quality and chastity. communicate us moment to order it and discover its numerous benefits.

What is Finerenone?

Finerenone also known as BAY 94-8862. it is a pharmaceutical component that's used in the product of medicines for the treatment of colorful cardiovascular and renal conditions. It's a picky antagonist of the mineralocorticoid receptor( MR) and exerts a potent inhibitory effect on the conditioning of aldosterone, a hormone that's involved in the regulation of blood pressure and fluid balance in the mortal body.

it is a largely effective and picky patch that has shown promising results in colorful clinical trials. It has been set up to reduce the threat of cardiorenal events and mortality in cases with habitual order complaint( CKD) and type 2 diabetes when combined with standard care. It has also been shown to ameliorate order function and reduce inflammation in cases with heart failure.

In addition to its remedial benefits, it has several advantages over other medicines in the same class. It has a longer partial- life, which means that it can be taken formerly daily rather of multiple times a day. It's also less likely to beget hyperkalemia( elevated situations of potassium in the blood), a implicit side effect of MR antagonists.

it is a pivotal component in the product of medicines that are used to treat a wide range of cardiovascular and renal conditions. It's presently being developed by colorful pharmaceutical companies around the world and is anticipated to come a crucial player in the treatment of CKD and affiliated conditions.

Overall, it offers a largely effective and picky treatment option for cases suffering from cardiovascular and renal conditions. Its implicit benefits, especially in terms of reducing the threat of cardiorenal events and perfecting order function, make it a promising seeker for farther exploration and development in the field of drug.

Basic Information

Product Name: Finerenone

CAS: 1050477-31-0

MF:C21H22N4O3

MW:378.42

MDL No.:MFCD29047135

Boiling point:554.7±50.0 °C(Predicted)

Density 1.29±0.1 g/cm3(Predicted)

Structural formula:

Origin: China

Delivery Time: in stock

Technical Specification

Package: 1kg;25kg; or according to your demands

Storage: Preserve in tight,light-resistant containers in cool place

Shelf Life:Powder: 2 years

Mechanism of action

Finerenone API is a picky, nonsteroidal mineralocorticoid receptor antagonist that's presently under development for the treatment of several cardiovascular and renal conditions. The medium of action is centered on its capability to block the list of aldosterone to the mineralocorticoid receptor, performing in the inhibition of sodium and water retention, and posterior reduction in blood pressure and forestallment of organ damage caused by aldosterone excess.

More specifically, the mineralocorticoid receptor is a nuclear receptor located in colorful apkins including the order, heart, and blood vessels. Aldosterone is a steroid hormone that acts on the mineralocorticoid receptor to regulate sodium and water balance throughout the body. Under normal conditions, aldosterone promotes sodium and water retention by its commerce with the mineralocorticoid receptor. still, in certain pathological conditions similar as cardiovascular complaint, hypertension and habitual order complaint, aldosterone excess leads to adverse goods, including inflammation, fibrosis, and end- organ damage.

it widely blocks the mineralocorticoid receptor and thereby inhibits the action of aldosterone. By doing so, it exerts renoprotective and cardioprotective goods by reducing inflammation, fibrosis, and end- organ damage. In addition, the inhibition of sodium and water retention by the leaguer of aldosterone- convinced mineralocorticoid receptor activation results in a drop in blood pressure, which is salutary in the Application of hypertension.

Overall, it represents a promising remedial option for the treatment of cardiovascular and renal conditions. Its picky medium of action and inhibitory goods on aldosterone- convinced organ damage make it a implicit volition to presently available curatives with a strong safety and efficacity profile.

Application

BAY 94-8862 is a largely effective and innovative drug that has been developed to treat a range of medical conditions, including heart and order complaint. It's a potent and picky antagonist of the mineralocorticoid receptor, which is involved in regulating fluid and electrolyte balance in the body. By inhibiting this receptor, it helps to help the dangerous goods of redundant sodium and water retention, which can lead to cardiovascular and renal damage.

One of the crucial Applications is in the Application of cases with habitual order complaint( CKD), particularly those with type 2 diabetes. CKD is a major global health issue that affects millions of people worldwide and can lead to serious complications, including order failure and heart complaint. it has been shown to significantly reduce the threat of order and cardiovascular events in these cases, making it an important tool in the fight against CKD.

Another important Application is in the treatment of heart failure with reduced ejection bit( HFrEF). HFrEF is a condition where the heart muscle is weakened and has difficulty pumping blood effectively, leading to symptoms similar as briefness of breath and fatigue. it has been shown to reduce the threat of cardiovascular death and hospitalization in cases with HFrEF, making it a precious addition to the treatment options available for this condition.

Overall, it represents a significant advancement in the treatment of cardiovascular and renal conditions and has the implicit to make a real difference in the lives of millions of people around the world. Its efficacity, safety, and selectivity make it a promising seeker for the Application of a range of conditions, and it's likely to come an essential tool in the magazine of healthcare professionals working to combat these conditions.

Packing & Shipping

Packing：

1kg/foil bag;5kg/carton;25kg/fiber drum; or packing as your request.

Customization:

l Customized logo

l Customized packaging

l Graphic customization

Shipping：

By Courier; By Air or By Sea, according to your demands

Payment Term

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Contact Yihui:

Yihui Pharmaceuticals, as a professional BAY 94-8862 manufacturer and supplier, is committed to delivering exceptional quality. Our adherence to international standards and prestigious certifications, including ISO, Kosher, Halal, underscores our dedication to product excellence. For inquiries or to purchase Finerenone API, please contact us immediately at sales@yihuipharm.com. Choose Yihui Pharmaceuticals for unparalleled quality and reliability in every batch.