We supply Sodium Stearyl Fumarate

We offer high- quality Sodium Stearyl Fumarate, which is used as a pharmaceutical excipient in tablet and capsule phrasings. It functions as a lubricant and helps in perfecting the inflow parcels of the phrasings by reducing the disunion between patches. It's also used as a disintegrant to promote tablet decomposition and enhance medicine release. Our product is manufactured using advanced technology and meets the loftiest quality norms. It's safe for use and has excellent stability. With our competitive pricing and timely delivery, we're your trusted supplier for it.

What's Sodium Stearyl Fumarate?

Sodium Octadecyl Fumarate( SSF) is a food- grade,multi-functional excipient that's generally used in the medicinal and food diligence. It's a white or out-white greasepaint, largely answerable in water and alcohol, and has excellent compressibility and lubricity.

SSF is a outgrowth of fumaric acid, which is a dicarboxylic acid involved in the cellular energy metabolism of mammals. It's synthesized by the response of stearic acid and fumaric acid, followed by neutralization with sodium bicarbonate or sodium hydroxide.

SSF has colorful operations in the pharmaceutical assiduity, primarily as a lubricant and a disintegrant in tablet phrasings. It helps to ameliorate the flowability, compressibility, and tablet hardness, and also enhances the decomposition and dissolution of the tablets in the gastrointestinal tract. It's generally used in high- cure, inadequately compressible medicines, and in phrasings that bear fast decomposition and dissolution, similar as orally disintegrating tablets, chewable tablets, and bouncy tablets.

In the food assiduity, SSF is used as a food cumulative and a processing aid, substantially in bakery products, crapola

, and confectionary. It's added to ameliorate the texture, shelf- life, and appearance of the products, and also to reduce the stickiness and adhesion of the dough and the paddings. It's generally honored as safe( GRAS) by the US Food and Drug Administration( FDA) and the European Food Safety Authority( EFSA).

SSF is a protean excipient that offers multitudinous benefits in colorful diligence. It's safe, effective, and cost-effective, and can ameliorate the quality and performance of the final products. It's extensively available in the request, and can be customized to meet specific expression conditions.

Basic Information

Product Name: Sodium Stearyl Fumarate

CAS: 4070-80-8

MF:C22H41NaO4

MW:392.56

EINECS:223-781-1

MDL No.:MFCD07782099

Structural formula:

Origin: China

Delivery Time: in stock

Technical Specification

Package: 1kg;10kg; 25kg or according to your demands

Storage: Preserve in tight,light-resistant containers in cool place

Shelf Life:Powder: 2 years

Application Areas

Sodium stearyl fumarate( C22H39NaO4) is a extensively used and important medicinal and food excipient. utmost of Sodium Octadecyl Fumarate can be absorbed during metabolism in creatures, and hydrolyzed to produce stearyl alcohol and stearic acid. A small part can be directly and snappily metabolized. It'snon-toxic andnon-irritating. In the pharmaceutical field, Sodium Octadecyl Fumaratee is added to pharmaceutical medications. It can be used as a lubricant for tablets and capsules, and can also form a defensive film in bouncy tablets. It can break the problems of stearate lubricants and ameliorate medicine decomposition and promote medicine dissolution. In the food field, FDA allows Sodium Octadecyl Fumarate to be directly added as a controller and stabilizer to foods for mortal consumption, similar as colorful baked foods, flour thickened foods, dried potatoes and reused grains, etc. The added quantum can regard for 0.2- 1.0 of the weight of the food.

Uses

it used as a lubricant for tablets and capsules, the common quantum is 0.5- 2.0, and it's also used in some foods. It's a hydrophilic lubricant, answerable in water, but its solubility is significantly affected by water temperature. It has veritably little solubility in water at 25 °C. still, white floating matter will appear on the face of the bouncy result, affecting the appearance and taste of the result, If the lozenge is slightly larger.

Function

Sodium Octadecyl Fumarate( C22H39NaO4) is a extensively used and important medicinal and food excipient. it can be absorbed during metabolism in creatures, hydrolyzed to produce stearyl alcohol and stearic acid, and a small part can be directly and snappily metabolized, which isnon-irritating. In the pharmaceutical field, it is added to pharmaceutical medications and can be used as a lubricant for tablets and capsules. It can also form a defensive film in bouncy tablets, which can break the problems of stearate lubricants. Columbium plays a part in perfecting medicine decomposition and promoting medicine dissolution.

Preparation

A system for preparing a Sodium Octadecyl Fumarate supplementary material comprises the following way S1, mixing maleic anhydride, octadecyl alcohol and a response detergent, and performing a ring- opening response at a temperature of 80 °C or over; S2, adding a conversion agent to the response system to perform a conversion response; S3, cooling to 40- 50 °C, trickling a sodium- containing alkaline result into the response system, and cooling and shaping after the stirring response to gain a crude Sodium Octadecyl Fumarate; S4, enriching the crude Sodium Octadecyl Fumarate to gain a Sodium Octadecyl Fumarate product.

Identification test

In the upward thin subcaste chromatography system of" Sodium stearoyl maleate and octadecyl alcohol test" in the following quality indicator analysis, the rate shift value( R1) of the large unheroic spot attained from the sample result should be harmonious with that attained from standard result A. The Rf value of the main color spot attained after scattering the thin subcaste plate with sulfuric acid and heating at 150 °C should be harmonious with that attained from standard result B.

Content analysis

Directly weigh about 250 mg of the sample, put it into a 50 ml conical beaker, add 1 ml of chloroform to blend, and also add 20 ml of glacial acetic acid to dissolve the sample. Add a many drops of quinaldine red test result( TS- 203) and titrate with 0.1 spook/ L perchloric acid glacial acetic acid result. Each mL of 0.1 spook/ L perchloric acid is original to 39.05 mg of this product( C22H39NaO4).

Toxicity

Safe for use in food (FDA, §172.826, 2000).

Usage Limits

FDA, §172.826 (2000): Yeast-fermented bakery products, 0.5% (based on flour); dehydrated potatoes, 1%; stabilizer for non-yeast-fermented bakery products, 1%; cereal products, 1%; starch or wheat flour thickener, 0.2%.

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