Vitamin k2 mk7 Powder
CAS No.: 2124-57-4
MOQ: 1kg
Assay:0.1%~5.0%
Packing:1kg/bag;10kg /drum; 25kg /drum
Supply Ability:1000Kg per month Used: Widely used in Pharmaceuticals, Nutraceuticals, Health functional foods, Dietary supplements, Skin-Whitening products, Cosmetics etc.
Delivery Time:in stock
Shelf Life: Two years
Payment: T/T, LC or DA
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Product Introduction
What is Vitamin k2 mk7 powder?
Vitamin k2 mk7 powder, also known as Menaquinone- 7, is a fat-answerable vitamin and one of the essential vitamins in the mortal body. In the mortal body, Vitamin K2 is primarily synthesized by intestinal bacteria and can also be set up in certain beast meat products and fermented products, similar as beast liver, fermented dairy products, and rubbish, with natto being the richest source. As aco-factor for gamma- glutamyl carboxylase, Vitamin K2 activates colorful vitamin K-dependent proteins, playing a pivotal part in cardiovascular and bone health.
Basic Information
Product name: Vitamin K2 MK-7;Menaquinone-7
Synonyms:MK-7; Menaquinone-7; Menaquinone 7; Vitamin MK 7 2-methyl-3-all-trans-farnesyl digeranyl-1,4-naphthoquinone
CAS No.: 2124-57-4
MF:C46H64O2
MW:649
Melting point: 54 °C
storage temp.: -20°C
Appearance:Yellow crystal powder
Stability: Stable for 2 years
Structural formula:
Quality standard
Item | Specification | Results |
Appearance: | Off white to light yellow powder | Complies |
Identification: | Positive by HPLC retention time Vitamin K2 MK-7 is soluble in n-hexane and | Complies |
Solubility: | ethanol, slightly soluble in methanol, and insoluble in water | Complies |
Carrier: | Maltodextrin | Complies |
Particle size: | NLT 90% through 80 mesh | Complies |
Loss on drying: | NMT 5.0% | 2.4% |
Heavy metals: | NMT 10 ppm | < 10 ppm |
Lead: | NMT 3 ppm | < 3 ppm |
Arsenic: | NMT 1 ppm | < 1 ppm |
Cadmium: | NMT 1 ppm | < 1 ppm |
Mercury: | NMT 0.1 ppm | < 0.1 ppm |
Menadione: | Not detectable by color reaction | Complies |
Assay (on dry basis): | NLT 1.00% (as C46H64O2) | 1.05% |
Total plate count:: | NMT 3,000 cfu/g | < 500 cfu/g |
Yeast & Mold: | NMT 300 cfu/g | < 100 cfu/g |
E. Coli: | Negative | Complies |
Salmonella: | Negative | Complies |
Staphylococcus Aureus: | Negative | Complies |
Conclusion | Qualified |
Assay of Vitamin K2(35),MK-7:
Vitamin K2(35),MK-7 , 0.1%, Oil
Vitamin K2(35) ,MK-7 , 0.1%, Powder
Vitamin K2(35) ,MK-7 , 0.2%, Oil
Vitamin K2(35) ,MK-7 , 0.2%, Powder
Vitamin K2(35) ,MK-7 , 0.45%, Oil
Vitamin K2(35) ,MK-7, 0.45%, Powder
Vitamin K2(35) ,MK-7 , 1.0%, Powder
Vitamin K2(35) ,MK-7 , 1.0%, Oil
Vitamin K2(35) ,MK-7 , 1.3%, Powder
Vitamin K2(35) ,MK-7 , 1.5%, Powder
Vitamin K2(35) ,MK-7, 1.3%, Oil
Vitamin K2(35) ,MK-7 , 1.5%, Oil
Vitamin K2(35) ,MK-7 , 1.5%,Powder
Vitamin K2(35) ,MK-7 , 0.5%, Oil
Vitamin K2(35) ,MK-7 , 5.0%, Powder
Discovery History
Vitamin k2 mk7 powder was discovered fairly late in the vitamin family. In 1929, Danish scientist Henrik Dam linked and uprooted Vitamin K from beast liver and cod liver oil painting, assuming its efficacity in precluding hemorrhages. In 1939, he purified Vitamin K1 from green lush vegetables. The 1943 Nobel Prize in Physiology or Medicine was awarded to Henrik Dam and Edward Adelbert Doisy for their benefactions to VitaminK. still, due to limited understanding of Vitamin K at that time, scientists were unfit to separate between Vitamin K1 and K2, and therefore distributed them both as Vitamin K. This limited perception redounded in Vitamin K2 being overlooked for several decades. It was not until 1975 that the distinctness between Vitamin K2( 35) and K1 gained attention, leading to in- depth exploration on Vitamin K2. Traditionally, Vitamin K was regarded as a pivotal element for blood clotting, as without it, we might witness nonstop bleeding from minor injuries. still, this solely represents the function of Vitamin K1 and doesn't encompass the entire Vitamin K family. All forms of Vitamin K are grounded on the naphthoquinone structure, and they're discerned into K1, K2, K3,etc., grounded on variations in side chain length and position. The subtle differences in side chain structure between Vitamin K1 and K2 lead to significant differences in their efficacity.
Food Sources
In modern diet, the average intake of Vitamin K2(35) is very low. Vitamin K2(35) is predominantly found in fermented foods such as tofu, cheese, and natto.
Physiological Functions and Effects:
(1) Anti-osteoporosis: The role of Menaquinone 7 powder is to activate osteocalcin, a matrix protein in bone. Under the influence of Vitamin K2(35), activated osteocalcin forms many calcium-binding sites on the protein. These activated calcium-binding sites can bind with the calcium entering the bone. When the active sites bind with calcium ions in the bone, the physiological bone formation process is completed, resulting in strong bones that can support body weight. Without sufficient Vitamin K2(35), osteocalcin cannot be activated, and calcium cannot bind to osteocalcin, preventing proper bone formation and leading to calcium loss. The lost calcium may deposit in various organs, causing calcification and leading to several diseases.
thus, it plays a significant part in fixing calcium in bones and precluding osteoporosis. Controlled trials have also shown that taking Vitamin K2( 35) supplements can decelerate down age-related decline in bone mineral viscosity. In addition, exploration in Japan has set up that Vitamin K2( 35) reduces chine fractures by 60, hipsterism fractures by 77, andnon-spine fractures by 81.
2) perfecting dental health One of the critical nonsupervisory proteins for dental health is osteocalcin, which is essential for bone metabolism and can be actuated by Vitamin K2 powder. Dentin is the calcified towel underneath the enamel on teeth, and osteocalcin can spark mechanisms that stimulate the growth of new dentin.
3) Assisting in cancer forestallment it can negatively regulate the exertion of tyrosine kinases and phosphatases associated with cellular carcinogenesis. It can also modulate nonsupervisory factors related to cell proliferation, eventually leading to cell cycle arrest and inhibition of excrescence growth.
4) perfecting diabetes Vitamin K2 mk7 bulk powder can upregulate the insulin gene and promote insulin release from pancreatic beta cells. This can ameliorate metabolic situations and contribute to the recovery of diabetic cases.
Deficiency Symptoms
After middle age, due to the decline in the body's physiological functions, the capability to synthesize Menaquinone- 7 in the bowel decreases dramatically. Ordinary food contains only trace quantities of Vitamin K2 bulk powder, which can not effectively condense the body's need for Menaquinone- 7 through diet. thus, middle-aged and senior individualities, as well as postmenopausal women, frequently suffer from severe Menaquinone- 7 insufficiency, which increases the threat of osteoporosis. To maintain bone health and help osteoporosis, it's essential to condense Menaquinone- 7 daily. The recommended diurnal input of Menaquinone- 7 for healthy grown-ups is roughly 50- 120 μg, while individualities with osteoporosis and sour bone health may bear an applicable increase in Vitamin K2 supplementation.
Production
The production of traditional Menaquinone-7 generally involves chemical synthesis, which has limitations such as restricted sources of chemical precursors, the generation of numerous isomers and byproducts, low yields, environmental pollution, and chemically synthesized Vitamin K2 Menaquinone-7 exhibiting lower activity levels. Higher activity natural Menaquinone-7 can only be obtained through microbial fermentation. Therefore, microbial fermentation is increasingly being favored by people and has vast application prospects.
Packing & Shipping
Packing:1kg/foil bag;5kg/carton;25kg/fiber drum;or packing as your request.
Customization:
Customized logo
Customized packaging
Graphic customization
Shipping:
Item | Quantity | ETA time | Shipping Method |
By Courier | ≤50kg | 7-15days | Fedex, DHL,UPS,TNT,EMS ect. Fast and convenient |
By Air | 50kg~200kg | 3-5days | Fast and cheap |
By Sea | Large quantity | 20-35days | Cheapest way |
Payment Term
Why Choose Xi'an Yihui?
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Our Advantage
Rich experience: we have 13 Years of professional experience;
Customers all over the world: sell to more than 100 countries;
Provide diversified products: the products have been applied to all major international brands in the fields of drugs, dietary supplements, cosmetics, animal nutrition and functional food.
Price advance: low MOQ with competitive price;
Quality certification: ISO; Halal; Kosher certified
After-sales service: Professional team 7*24 hours customer service.
In conclusion
In summary, as a professional Vitamin k2 mk7 powder manufacturer, we have advanced technology, scale advantage, the best quality, rich production experience, and excellent services. These advantages will make our Menaquinone-7 stand out in the market competition and win more customer trust and support. if you need Vitamin K2 Mk7, pls feel free to contact us any time. we will reply you asap.
our contact information:
E-mail: sales@yihuipharm.com
Tel: 0086-29-89695240
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